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Items: 1 to 20 of 360

1.

Precise prediction of activators for the human constitutive androstane receptor using structure-based three-dimensional quantitative structure-activity relationship methods.

Kato H, Yamaotsu N, Iwazaki N, Okamura S, Kume T, Hirono S.

Drug Metab Pharmacokinet. 2017 Feb 9. pii: S1347-4367(16)30099-4. doi: 10.1016/j.dmpk.2017.02.001. [Epub ahead of print]

PMID:
28412023
2.

Current advance and future foresight of surgical treatment for pancreatic cancer.

Hirono S, Yamaue H.

Nihon Shokakibyo Gakkai Zasshi. 2017;114(4):607-616. doi: 10.11405/nisshoshi.114.607. No abstract available.

PMID:
28381777
3.

Phase I Study of Nab-Paclitaxel plus Gemcitabine as Neoadjuvant Therapy for Borderline Resectable Pancreatic Cancer.

Okada KI, Hirono S, Kawai M, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Hayami S, Yamaue H.

Anticancer Res. 2017 Feb;37(2):853-858.

PMID:
28179342
4.

The Pluripotent Stem-Cell Marker Alkaline Phosphatase is Highly Expressed in Refractory Glioblastoma with DNA Hypomethylation.

Iwadate Y, Suganami A, Tamura Y, Matsutani T, Hirono S, Shinozaki N, Hiwasa T, Takiguchi M, Saeki N.

Neurosurgery. 2017 Feb 1;80(2):248-256. doi: 10.1093/neuros/nyw026. No abstract available.

PMID:
28173571
5.

Multi-step virtual screening to develop selective DYRK1A inhibitors.

Koyama T, Yamaotsu N, Nakagome I, Ozawa SI, Yoshida T, Hayakawa D, Hirono S.

J Mol Graph Model. 2017 Mar;72:229-239. doi: 10.1016/j.jmgm.2017.01.014. Epub 2017 Jan 15.

PMID:
28129593
6.

Factors Associated With Invasive Intraductal Papillary Mucinous Carcinoma of the Pancreas.

Hirono S, Kawai M, Okada KI, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Yanagisawa A, Yamaue H.

JAMA Surg. 2017 Mar 15;152(3):e165054. doi: 10.1001/jamasurg.2016.5054. Epub 2017 Mar 15.

PMID:
28122068
7.

Partial clamping of the infrahepatic inferior vena cava for blood loss reduction during anatomic liver resection: A prospective, randomized, controlled trial.

Ueno M, Kawai M, Hayami S, Hirono S, Okada KI, Uchiyama K, Yamaue H.

Surgery. 2017 Jan 19. pii: S0039-6060(16)30861-3. doi: 10.1016/j.surg.2016.12.010. [Epub ahead of print]

PMID:
28111044
8.

Value of apparent diffusion coefficient prior to neoadjuvant therapy is a predictor of histologic response in patients with borderline resectable pancreatic carcinoma.

Okada KI, Hirono S, Kawai M, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Hayami S, Kojima F, Yamaue H.

J Hepatobiliary Pancreat Sci. 2017 Mar;24(3):161-168. doi: 10.1002/jhbp.430.

PMID:
28064462
9.

Phase II clinical trial using novel peptide cocktail vaccine as a postoperative adjuvant treatment for surgically resected pancreatic cancer patients.

Miyazawa M, Katsuda M, Maguchi H, Katanuma A, Ishii H, Ozaka M, Yamao K, Imaoka H, Kawai M, Hirono S, Okada KI, Yamaue H.

Int J Cancer. 2017 Feb 15;140(4):973-982. doi: 10.1002/ijc.30510. Epub 2016 Nov 21.

PMID:
27861852
10.

Treatment Strategy for Borderline Resectable Pancreatic Cancer With Radiographic Artery Involvement.

Hirono S, Kawai M, Okada KI, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Yamaue H.

Pancreas. 2016 Nov;45(10):1438-1446.

PMID:
27088490
11.

Proposed Nomogram Predicting the Individual Risk of Malignancy in the Patients With Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Jang JY, Park T, Lee S, Kim Y, Lee SY, Kim SW, Kim SC, Song KB, Yamamoto M, Hatori T, Hirono S, Satoi S, Fujii T, Hirano S, Hashimoto Y, Shimizu Y, Choi DW, Choi SH, Heo JS, Motoi F, Matsumoto I, Lee WJ, Kang CM, Han HS, Yoon YS, Sho M, Nagano H, Honda G, Kim SG, Yu HC, Chung JC, Nagakawa Y, Seo HI, Yamaue H.

Ann Surg. 2016 Sep 6. [Epub ahead of print]

PMID:
27607098
12.

Impact of treatment duration of neoadjuvant FIRINOX in patients with borderline resectable pancreatic cancer: a pilot trial.

Okada K, Kawai M, Hirono S, Satoi S, Yanagimoto H, Ioka T, Miyazawa M, Shimizu A, Kitahata Y, Yamaue H.

Cancer Chemother Pharmacol. 2016 Oct;78(4):719-26. doi: 10.1007/s00280-016-3121-8. Epub 2016 Aug 8.

PMID:
27501851
13.

Molecular Orbital Study of the Formation of Intramolecular Hydrogen Bonding of a Ligand Molecule in a Protein Aromatic Hydrophobic Pocket.

Koseki J, Gouda H, Hirono S.

Chem Pharm Bull (Tokyo). 2016;64(7):1031-5. doi: 10.1248/cpb.c16-00126.

14.

Prediction of three-dimensional structures and structural flexibilities of wild-type and mutant cytochrome P450 1A2 using molecular dynamics simulations.

Watanabe Y, Fukuyoshi S, Hiratsuka M, Yamaotsu N, Hirono S, Takahashi O, Oda A.

J Mol Graph Model. 2016 Jul;68:48-56. doi: 10.1016/j.jmgm.2016.06.006. Epub 2016 Jun 16.

PMID:
27371932
15.

Depth of Hepatic Infiltration and Lymph Node Swelling as Factors for Considering Surgery for T2-4 Gallbladder Carcinoma Patients.

Okada K, Kawai M, Ueno M, Hirono S, Miyazawa M, Hayami S, Shimizu A, Shigekawa Y, Kitahata Y, Miyamoto A, Yamaue H.

Anticancer Res. 2016 Jun;36(6):3075-80.

PMID:
27272830
16.

Long-term surveillance is necessary after operative resection for intraductal papillary mucinous neoplasm of the pancreas.

Hirono S, Kawai M, Okada K, Miyazawa M, Shimizu A, Kitahata Y, Ueno M, Yanagisawa A, Yamaue H.

Surgery. 2016 Aug;160(2):306-17. doi: 10.1016/j.surg.2016.04.007. Epub 2016 May 25.

PMID:
27236360
17.

Transforming growth factor-β and stem cell markers are highly expressed around necrotic areas in glioblastoma.

Iwadate Y, Matsutani T, Hirono S, Shinozaki N, Saeki N.

J Neurooncol. 2016 Aug;129(1):101-7. doi: 10.1007/s11060-016-2145-6. Epub 2016 May 18.

PMID:
27193555
18.

Grade B pancreatic fistulas do not affect survival after pancreatectomy for pancreatic cancer: A multicenter observational study.

Kawai M, Murakami Y, Motoi F, Sho M, Satoi S, Matsumoto I, Honda G, Hirono S, Okada K, Unno M, Nakajima Y, Uemura K, Kwon AH, Fukumoto T, Kurata M, Yamaue H.

Surgery. 2016 Aug;160(2):293-305. doi: 10.1016/j.surg.2016.02.032. Epub 2016 Apr 13.

PMID:
27083480
19.

Molecular Dynamics Simulations to Investigate the Influences of Amino Acid Mutations on Protein Three-Dimensional Structures of Cytochrome P450 2D6.1, 2, 10, 14A, 51, and 62.

Fukuyoshi S, Kometani M, Watanabe Y, Hiratsuka M, Yamaotsu N, Hirono S, Manabe N, Takahashi O, Oda A.

PLoS One. 2016 Apr 5;11(4):e0152946. doi: 10.1371/journal.pone.0152946. eCollection 2016.

20.

Genomic Sequencing Identifies ELF3 as a Driver of Ampullary Carcinoma.

Yachida S, Wood LD, Suzuki M, Takai E, Totoki Y, Kato M, Luchini C, Arai Y, Nakamura H, Hama N, Elzawahry A, Hosoda F, Shirota T, Morimoto N, Hori K, Funazaki J, Tanaka H, Morizane C, Okusaka T, Nara S, Shimada K, Hiraoka N, Taniguchi H, Higuchi R, Oshima M, Okano K, Hirono S, Mizuma M, Arihiro K, Yamamoto M, Unno M, Yamaue H, Weiss MJ, Wolfgang CL, Furukawa T, Nakagama H, Vogelstein B, Kiyono T, Hruban RH, Shibata T.

Cancer Cell. 2016 Feb 8;29(2):229-40. doi: 10.1016/j.ccell.2015.12.012. Epub 2016 Jan 21.

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