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Items: 1 to 20 of 44

1.

Lipidomic profiling of patient-specific iPSC-derived hepatocyte-like cells.

Kiamehr M, Viiri LE, Vihervaara T, Koistinen KM, Hilvo M, Ekroos K, Käkelä R, Aalto-Setälä K.

Dis Model Mech. 2017 Sep 1;10(9):1141-1153. doi: 10.1242/dmm.030841. Epub 2017 Jul 21.

2.

Liver-specific deletion of the Plpp3 gene alters plasma lipid composition and worsens atherosclerosis in apoE-/- mice.

Busnelli M, Manzini S, Hilvo M, Parolini C, Ganzetti GS, Dellera F, Ekroos K, Jänis M, Escalante-Alcalde D, Sirtori CR, Laaksonen R, Chiesa G.

Sci Rep. 2017 Mar 14;7:44503. doi: 10.1038/srep44503.

3.

Circulating Ceramides Predict Cardiovascular Outcomes in the Population-Based FINRISK 2002 Cohort.

Havulinna AS, Sysi-Aho M, Hilvo M, Kauhanen D, Hurme R, Ekroos K, Salomaa V, Laaksonen R.

Arterioscler Thromb Vasc Biol. 2016 Dec;36(12):2424-2430. Epub 2016 Oct 20.

PMID:
27765765
4.

Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol.

Laaksonen R, Ekroos K, Sysi-Aho M, Hilvo M, Vihervaara T, Kauhanen D, Suoniemi M, Hurme R, März W, Scharnagl H, Stojakovic T, Vlachopoulou E, Lokki ML, Nieminen MS, Klingenberg R, Matter CM, Hornemann T, Jüni P, Rodondi N, Räber L, Windecker S, Gencer B, Pedersen ER, Tell GS, Nygård O, Mach F, Sinisalo J, Lüscher TF.

Eur Heart J. 2016 Jul 1;37(25):1967-76. doi: 10.1093/eurheartj/ehw148. Epub 2016 Apr 28.

5.

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.

Aho V, Ollila HM, Kronholm E, Bondia-Pons I, Soininen P, Kangas AJ, Hilvo M, Seppälä I, Kettunen J, Oikonen M, Raitoharju E, Hyötyläinen T, Kähönen M, Viikari JS, Härmä M, Sallinen M, Olkkonen VM, Alenius H, Jauhiainen M, Paunio T, Lehtimäki T, Salomaa V, Orešič M, Raitakari OT, Ala-Korpela M, Porkka-Heiskanen T.

Sci Rep. 2016 Apr 22;6:24828. doi: 10.1038/srep24828.

6.

Accumulated Metabolites of Hydroxybutyric Acid Serve as Diagnostic and Prognostic Biomarkers of Ovarian High-Grade Serous Carcinomas.

Hilvo M, de Santiago I, Gopalacharyulu P, Schmitt WD, Budczies J, Kuhberg M, Dietel M, Aittokallio T, Markowetz F, Denkert C, Sehouli J, Frezza C, Darb-Esfahani S, Braicu EI.

Cancer Res. 2016 Feb 15;76(4):796-804. doi: 10.1158/0008-5472.CAN-15-2298. Epub 2015 Dec 18.

7.

The Metabolome in Finnish Carriers of the MYBPC3-Q1061X Mutation for Hypertrophic Cardiomyopathy.

Jørgenrud B, Jalanko M, Heliö T, Jääskeläinen P, Laine M, Hilvo M, Nieminen MS, Laakso M, Hyötyläinen T, Orešič M, Kuusisto J.

PLoS One. 2015 Aug 12;10(8):e0134184. doi: 10.1371/journal.pone.0134184. eCollection 2015.

8.

Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice.

Skorve J, Hilvo M, Vihervaara T, Burri L, Bohov P, Tillander V, Bjørndal B, Suoniemi M, Laaksonen R, Ekroos K, Berge RK, Alexson SE.

Lipids Health Dis. 2015 Aug 11;14:88. doi: 10.1186/s12944-015-0086-2.

9.

The metabolic alterations of cancer cells.

Sciacovelli M, Gaude E, Hilvo M, Frezza C.

Methods Enzymol. 2014;542:1-23. doi: 10.1016/B978-0-12-416618-9.00001-7. Review.

PMID:
24862258
10.

Steroid and steroid glucuronide profiles in urine during pregnancy determined by liquid chromatography-electrospray ionization-tandem mass spectrometry.

Jäntti SE, Hartonen M, Hilvo M, Nygren H, Hyötyläinen T, Ketola RA, Kostiainen R.

Anal Chim Acta. 2013 Nov 13;802:56-66. doi: 10.1016/j.aca.2013.09.034. Epub 2013 Sep 30.

PMID:
24176505
11.

Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients.

Hilvo M, Gade S, Hyötyläinen T, Nekljudova V, Seppänen-Laakso T, Sysi-Aho M, Untch M, Huober J, von Minckwitz G, Denkert C, Orešič M, Loibl S.

Int J Cancer. 2014 Apr 1;134(7):1725-33. doi: 10.1002/ijc.28491. Epub 2013 Oct 8.

12.

Characterization, bioinformatic analysis and dithiocarbamate inhibition studies of two new α-carbonic anhydrases, CAH1 and CAH2, from the fruit fly Drosophila melanogaster.

Syrjänen L, Tolvanen ME, Hilvo M, Vullo D, Carta F, Supuran CT, Parkkila S.

Bioorg Med Chem. 2013 Mar 15;21(6):1516-21. doi: 10.1016/j.bmc.2012.08.046. Epub 2012 Aug 31.

PMID:
22989910
13.

Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer.

Jerby L, Wolf L, Denkert C, Stein GY, Hilvo M, Oresic M, Geiger T, Ruppin E.

Cancer Res. 2012 Nov 15;72(22):5712-20. doi: 10.1158/0008-5472.CAN-12-2215. Epub 2012 Sep 17.

14.

Remodeling of central metabolism in invasive breast cancer compared to normal breast tissue - a GC-TOFMS based metabolomics study.

Budczies J, Denkert C, Müller BM, Brockmöller SF, Klauschen F, Györffy B, Dietel M, Richter-Ehrenstein C, Marten U, Salek RM, Griffin JL, Hilvo M, Orešič M, Wohlgemuth G, Fiehn O.

BMC Genomics. 2012 Jul 23;13:334. doi: 10.1186/1471-2164-13-334.

15.

Metabolomics of human breast cancer: new approaches for tumor typing and biomarker discovery.

Denkert C, Bucher E, Hilvo M, Salek R, Orešič M, Griffin J, Brockmöller S, Klauschen F, Loibl S, Barupal DK, Budczies J, Iljin K, Nekljudova V, Fiehn O.

Genome Med. 2012 Apr 30;4(4):37.

16.

Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress.

Ketola K, Hilvo M, Hyötyläinen T, Vuoristo A, Ruskeepää AL, Orešič M, Kallioniemi O, Iljin K.

Br J Cancer. 2012 Jan 3;106(1):99-106. doi: 10.1038/bjc.2011.530.

17.

Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins.

Vainio P, Lehtinen L, Mirtti T, Hilvo M, Seppänen-Laakso T, Virtanen J, Sankila A, Nordling S, Lundin J, Rannikko A, Orešič M, Kallioniemi O, Iljin K.

Oncotarget. 2011 Dec;2(12):1176-90.

18.

15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.

Lehtinen L, Vainio P, Wikman H, Reemts J, Hilvo M, Issa R, Pollari S, Brandt B, Oresic M, Pantel K, Kallioniemi O, Iljin K.

J Pathol. 2012 Mar;226(4):674-86. doi: 10.1002/path.3956. Epub 2012 Jan 17.

PMID:
22072156
19.

Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer-link to patient survival, hormone receptor status, and metabolic profiling.

Brockmöller SF, Bucher E, Müller BM, Budczies J, Hilvo M, Griffin JL, Orešič M, Kallioniemi O, Iljin K, Loibl S, Darb-Esfahani S, Sinn BV, Klauschen F, Prinzler J, Bangemann N, Ismaeel F, Fiehn O, Dietel M, Denkert C.

J Proteome Res. 2012 Feb 3;11(2):850-60. doi: 10.1021/pr200685r. Epub 2011 Dec 15.

PMID:
22070544
20.

Brain phenotype of carbonic anhydrase IX-deficient mice.

Pan PW, Parkkila AK, Autio S, Hilvo M, Sormunen R, Pastorekova S, Pastorek J, Haapasalo H, Parkkila S.

Transgenic Res. 2012 Feb;21(1):163-76. doi: 10.1007/s11248-011-9520-z. Epub 2011 May 6.

PMID:
21547424

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