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Phase III Study of Surgery Versus Definitive Concurrent Chemoradiotherapy Boost in Patients With Resectable Stage IIIA(N2) and Selected IIIB Non-Small-Cell Lung Cancer After Induction Chemotherapy and Concurrent Chemoradiotherapy (ESPATUE).

Eberhardt WE, Pöttgen C, Gauler TC, Friedel G, Veit S, Heinrich V, Welter S, Budach W, Spengler W, Kimmich M, Fischer B, Schmidberger H, De Ruysscher D, Belka C, Cordes S, Hepp R, Lütke-Brintrup D, Lehmann N, Schuler M, Jöckel KH, Stamatis G, Stuschke M.

J Clin Oncol. 2015 Dec 10;33(35):4194-201. doi: 10.1200/JCO.2015.62.6812.


Deep inspiration breath-hold (DIBH) radiotherapy in left-sided breast cancer: Dosimetrical comparison and clinical feasibility in 20 patients.

Hepp R, Ammerpohl M, Morgenstern C, Nielinger L, Erichsen P, Abdallah A, Galalae R.

Strahlenther Onkol. 2015 Sep;191(9):710-6. doi: 10.1007/s00066-015-0838-y.


GINIP, a Gαi-interacting protein, functions as a key modulator of peripheral GABAB receptor-mediated analgesia.

Gaillard S, Lo Re L, Mantilleri A, Hepp R, Urien L, Malapert P, Alonso S, Deage M, Kambrun C, Landry M, Low SA, Alloui A, Lambolez B, Scherrer G, Le Feuvre Y, Bourinet E, Moqrich A.

Neuron. 2014 Oct 1;84(1):123-36. doi: 10.1016/j.neuron.2014.08.056.


Noradrenalin and dopamine receptors both control cAMP-PKA signaling throughout the cerebral cortex.

Nomura S, Bouhadana M, Morel C, Faure P, Cauli B, Lambolez B, Hepp R.

Front Cell Neurosci. 2014 Aug 21;8:247. doi: 10.3389/fncel.2014.00247.


Erratum to: Glutamate receptors of the delta family are widely expressed in the adult brain.

Hepp R, Hay YA, Aguado C, Lujan R, Dauphinot L, Potier MC, Nomura S, Poirel O, El Mestikawy S, Lambolez B, Tricoire L.

Brain Struct Funct. 2015 Nov;220(6):3757. doi: 10.1007/s00429-014-0879-5. No abstract available.


Glutamate receptors of the delta family are widely expressed in the adult brain.

Hepp R, Hay YA, Aguado C, Lujan R, Dauphinot L, Potier MC, Nomura S, Poirel O, El Mestikawy S, Lambolez B, Tricoire L.

Brain Struct Funct. 2015 Sep;220(5):2797-815. doi: 10.1007/s00429-014-0827-4. Erratum in: Brain Struct Funct. 2015 Nov;220(6):3757.


Single-fluorophore biosensors based on conformation-sensitive GFP variants.

Bonnot A, Guiot E, Hepp R, Cavellini L, Tricoire L, Lambolez B.

FASEB J. 2014 Mar;28(3):1375-85. doi: 10.1096/fj.13-240507.


Staging of the mediastinum: are we already there?

Eberhardt WE, Hepp R.

J Thorac Oncol. 2013 Sep;8(9):1114-5. doi: 10.1097/JTO.0b013e3182a40596. No abstract available.


Folylpoly-glutamate synthetase expression is associated with tumor response and outcome from pemetrexed-based chemotherapy in malignant pleural mesothelioma.

Christoph DC, Asuncion BR, Mascaux C, Tran C, Lu X, Wynes MW, Gauler TC, Wohlschlaeger J, Theegarten D, Neumann V, Hepp R, Welter S, Stamatis G, Tannapfel A, Schuler M, Eberhardt WE, Hirsch FR.

J Thorac Oncol. 2012 Sep;7(9):1440-8.


βV-tubulin expression is associated with outcome following taxane-based chemotherapy in non-small cell lung cancer.

Christoph DC, Kasper S, Gauler TC, Loesch C, Engelhard M, Theegarten D, Poettgen C, Hepp R, Peglow A, Loewendick H, Welter S, Stamatis G, Hirsch FR, Schuler M, Eberhardt WE, Wohlschlaeger J.

Br J Cancer. 2012 Aug 21;107(5):823-30. doi: 10.1038/bjc.2012.324.


Megavoltage computed tomography image guidance with helical tomotherapy in patients with vertebral tumors: analysis of factors influencing interobserver variability.

Levegrün S, Pöttgen C, Jawad JA, Berkovic K, Hepp R, Stuschke M.

Int J Radiat Oncol Biol Phys. 2013 Feb 1;85(2):561-9. doi: 10.1016/j.ijrobp.2012.04.010.


VIP, CRF, and PACAP act at distinct receptors to elicit different cAMP/PKA dynamics in the neocortex.

Hu E, Demmou L, Cauli B, Gallopin T, Geoffroy H, Harris-Warrick RM, Paupardin-Tritsch D, Lambolez B, Vincent P, Hepp R.

Cereb Cortex. 2011 Mar;21(3):708-18. doi: 10.1093/cercor/bhq143.


Chemotherapy in stage III non-small cell lung cancer.

Eberhardt WE, Hepp R.

Eur J Cancer. 2009 Sep;45 Suppl 1:126-36. doi: 10.1016/S0959-8049(09)70024-3. No abstract available.


Breast cancer in Latin America: results of the Latin American and Caribbean Society of Medical Oncology/Breast Cancer Research Foundation expert survey.

Cazap E, Buzaid AC, Garbino C, de la Garza J, Orlandi FJ, Schwartsmann G, Vallejos C, Guercovich A; Latin American and Caribbean Society of Medical Oncology..

Cancer. 2008 Oct 15;113(8 Suppl):2359-65. doi: 10.1002/cncr.23834.


Calmodulin dynamically regulates the trafficking of the metabotropic glutamate receptor mGluR5.

Lee JH, Lee J, Choi KY, Hepp R, Lee JY, Lim MK, Chatani-Hinze M, Roche PA, Kim DG, Ahn YS, Kim CH, Roche KW.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12575-80. doi: 10.1073/pnas.0712033105.


Phosphodiesterase type 2 and the homeostasis of cyclic GMP in living thalamic neurons.

Hepp R, Tricoire L, Hu E, Gervasi N, Paupardin-Tritsch D, Lambolez B, Vincent P.

J Neurochem. 2007 Sep;102(6):1875-86.


Dynamics of protein kinase A signaling at the membrane, in the cytosol, and in the nucleus of neurons in mouse brain slices.

Gervasi N, Hepp R, Tricoire L, Zhang J, Lambolez B, Paupardin-Tritsch D, Vincent P.

J Neurosci. 2007 Mar 14;27(11):2744-50.


The role of surgery in stage IIIA non-small cell lung cancer.

Eberhardt WE, Hepp R, Stamatis G.

Hematol Oncol Clin North Am. 2005 Apr;19(2):303-19, vi-vii. Review.


Phosphorylation of SNAP-23 regulates exocytosis from mast cells.

Hepp R, Puri N, Hohenstein AC, Crawford GL, Whiteheart SW, Roche PA.

J Biol Chem. 2005 Feb 25;280(8):6610-20.


New targeted treatments in lung cancer--overview of clinical trials.

Korfee S, Gauler T, Hepp R, Pöttgen C, Eberhardt W.

Lung Cancer. 2004 Aug;45 Suppl 2:S199-208. Review.

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