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Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells.

Sarwar M, Semenas J, Miftakhova R, Simoulis A, Robinson B, Gjörloff Wingren A, Mongan NP, Heery DM, Johnsson H, Abrahamsson PA, Dizeyi N, Luo J, Persson JL.

Oncotarget. 2016 Sep 27;7(39):63065-63081. doi: 10.18632/oncotarget.11757.


MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.

Nilsson EM, Laursen KB, Whitchurch J, McWilliam A, Ødum N, Persson JL, Heery DM, Gudas LJ, Mongan NP.

Oncotarget. 2015 Nov 3;6(34):35710-25. doi: 10.18632/oncotarget.5958.


Correction: PRAME Is a Golgi-Targeted Protein That Associates with the Elongin BC Complex and Is Upregulated by Interferon-Gamma and Bacterial PAMPs.

Wadelin FR, Fulton J, Collins HM, Tertipis N, Bottley A, Spriggs KA, Falcone FH, Heery DM.

PLoS One. 2015 Jun 12;10(6):e0129297. doi: 10.1371/journal.pone.0129297. eCollection 2015. No abstract available.


Potentiation of latent inhibition by haloperidol and clozapine is attenuated in Dopamine D2 receptor (Drd-2)-deficient mice: do antipsychotics influence learning to ignore irrelevant stimuli via both Drd-2 and non-Drd-2 mechanisms?

O'Callaghan MJ, Bay-Richter C, O'Tuathaigh CM, Heery DM, Waddington JL, Moran PM.

J Psychopharmacol. 2014 Oct;28(10):973-7. doi: 10.1177/0269881114544774. Epub 2014 Aug 13.


The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.

Dreveny I, Deeves SE, Fulton J, Yue B, Messmer M, Bhattacharya A, Collins HM, Heery DM.

Nucleic Acids Res. 2014 Jan;42(2):822-35. doi: 10.1093/nar/gkt931. Epub 2013 Oct 22.


A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.

Chan CM, Fulton J, Montiel-Duarte C, Collins HM, Bharti N, Wadelin FR, Moran PM, Mongan NP, Heery DM.

Nucleic Acids Res. 2013 Nov;41(21):9663-79. doi: 10.1093/nar/gkt761. Epub 2013 Aug 23.


PRAME is a golgi-targeted protein that associates with the Elongin BC complex and is upregulated by interferon-gamma and bacterial PAMPs.

Wadelin FR, Fulton J, Collins HM, Tertipis N, Bottley A, Spriggs KA, Falcone FH, Heery DM.

PLoS One. 2013;8(2):e58052. doi: 10.1371/journal.pone.0058052. Epub 2013 Feb 27. Erratum in: PLoS One. 2015;10(6):e0129297.


D-amphetamine and antipsychotic drug effects on latent inhibition in mice lacking dopamine D2 receptors.

Bay-Richter C, O'Callaghan MJ, Mathur N, O'Tuathaigh CM, Heery DM, Fone KC, Waddington JL, Moran PM.

Neuropsychopharmacology. 2013 Jul;38(8):1512-20. doi: 10.1038/npp.2013.50. Epub 2013 Feb 19.


Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells.

Collins HM, Abdelghany MK, Messmer M, Yue B, Deeves SE, Kindle KB, Mantelingu K, Aslam A, Winkler GS, Kundu TK, Heery DM.

BMC Cancer. 2013 Jan 29;13:37. doi: 10.1186/1471-2407-13-37.


Interleukin-4-inducing principle from Schistosoma mansoni eggs contains a functional C-terminal nuclear localization signal necessary for nuclear translocation in mammalian cells but not for its uptake.

Kaur I, Schramm G, Everts B, Scholzen T, Kindle KB, Beetz C, Montiel-Duarte C, Blindow S, Jones AT, Haas H, Stolnik S, Heery DM, Falcone FH.

Infect Immun. 2011 Apr;79(4):1779-88. doi: 10.1128/IAI.01048-10. Epub 2011 Jan 10.


Leucine-rich repeat protein PRAME: expression, potential functions and clinical implications for leukaemia.

Wadelin F, Fulton J, McEwan PA, Spriggs KA, Emsley J, Heery DM.

Mol Cancer. 2010 Aug 27;9:226. doi: 10.1186/1476-4598-9-226. Review.


p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication.

Cannell IG, Kong YW, Johnston SJ, Chen ML, Collins HM, Dobbyn HC, Elia A, Kress TR, Dickens M, Clemens MJ, Heery DM, Gaestel M, Eilers M, Willis AE, Bushell M.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5375-80. doi: 10.1073/pnas.0910015107. Epub 2010 Mar 8.


SUMOylation regulates the nuclear mobility of CREB binding protein and its association with nuclear bodies in live cells.

Ryan CM, Kindle KB, Collins HM, Heery DM.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):1136-41. doi: 10.1016/j.bbrc.2009.12.040. Epub 2009 Dec 16.


Enhanced latent inhibition in dopamine receptor-deficient mice is sex-specific for the D1 but not D2 receptor subtype: implications for antipsychotic drug action.

Bay-Richter C, O'Tuathaigh CM, O'Sullivan G, Heery DM, Waddington JL, Moran PM.

Int J Neuropsychopharmacol. 2009 Apr;12(3):403-14. doi: 10.1017/S1461145708009656. Epub 2008 Nov 17.


ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases.

Lopez-Garcia J, Periyasamy M, Thomas RS, Christian M, Leao M, Jat P, Kindle KB, Heery DM, Parker MG, Buluwela L, Kamalati T, Ali S.

Nucleic Acids Res. 2006;34(21):6126-36. Epub 2006 Nov 3.


T:G mismatch-specific thymine-DNA glycosylase (TDG) as a coregulator of transcription interacts with SRC1 family members through a novel tyrosine repeat motif.

Lucey MJ, Chen D, Lopez-Garcia J, Hart SM, Phoenix F, Al-Jehani R, Alao JP, White R, Kindle KB, Losson R, Chambon P, Parker MG, Schär P, Heery DM, Buluwela L, Ali S.

Nucleic Acids Res. 2005 Nov 10;33(19):6393-404. Print 2005.


MOZ-TIF2 inhibits transcription by nuclear receptors and p53 by impairment of CBP function.

Kindle KB, Troke PJ, Collins HM, Matsuda S, Bossi D, Bellodi C, Kalkhoven E, Salomoni P, Pelicci PG, Minucci S, Heery DM.

Mol Cell Biol. 2005 Feb;25(3):988-1002.


The AF1 and AF2 domains of the androgen receptor interact with distinct regions of SRC1.

Bevan CL, Hoare S, Claessens F, Heery DM, Parker MG.

Mol Cell Biol. 1999 Dec;19(12):8383-92.


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