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Items: 1 to 20 of 41


Regulatory RNPs: a novel class of ribonucleoproteins that potentially contribute to ribosome heterogeneity.

Poole AR, Vicino I, Adachi H, Yu YT, Hebert MD.

Biol Open. 2017 Sep 15;6(9):1342-1354. doi: 10.1242/bio.028092.


Towards an understanding of regulating Cajal body activity by protein modification.

Hebert MD, Poole AR.

RNA Biol. 2017 Jun 3;14(6):761-778. doi: 10.1080/15476286.2016.1243649. Epub 2016 Oct 7. Review.


Identification of processing elements and interactors implicate SMN, coilin and the pseudogene-encoded coilp1 in telomerase and box C/D scaRNP biogenesis.

Poole AR, Enwerem II, Vicino IA, Coole JB, Smith SV, Hebert MD.

RNA Biol. 2016 Oct 2;13(10):955-972. Epub 2016 Jul 15.


SMN and coilin negatively regulate dyskerin association with telomerase RNA.

Poole AR, Hebert MD.

Biol Open. 2016 Jun 15;5(6):726-35. doi: 10.1242/bio.018804.


Cajal body proteins differentially affect the processing of box C/D scaRNPs.

Enwerem II, Wu G, Yu YT, Hebert MD.

PLoS One. 2015 Apr 13;10(4):e0122348. doi: 10.1371/journal.pone.0122348. eCollection 2015.


Coilin association with Box C/D scaRNA suggests a direct role for the Cajal body marker protein in scaRNP biogenesis.

Enwerem II, Velma V, Broome HJ, Kuna M, Begum RA, Hebert MD.

Biol Open. 2014 Apr 15;3(4):240-9. doi: 10.1242/bio.20147443.


Phosphorylation regulates coilin activity and RNA association.

Broome HJ, Carrero ZI, Douglas HE, Hebert MD.

Biol Open. 2013 Feb 26;2(4):407-15. doi: 10.1242/bio.20133863. Print 2013 Apr 15.


Signals controlling Cajal body assembly and function.

Hebert MD.

Int J Biochem Cell Biol. 2013 Jul;45(7):1314-7. doi: 10.1016/j.biocel.2013.03.019. Epub 2013 Apr 10. Review.


Coilin displays differential affinity for specific RNAs in vivo and is linked to telomerase RNA biogenesis.

Broome HJ, Hebert MD.

J Mol Biol. 2013 Feb 22;425(4):713-24. doi: 10.1016/j.jmb.2012.12.014. Epub 2012 Dec 27.


Regulated specific proteolysis of the Cajal body marker protein coilin.

Velma V, Broome HJ, Hebert MD.

Chromosoma. 2012 Dec;121(6):629-42. doi: 10.1007/s00412-012-0387-4. Epub 2012 Oct 14.


Coilin levels modulate cell cycle progression and γH2AX levels in etoposide treated U2OS cells.

Velma V, Carrero ZI, Allen CB, Hebert MD.

FEBS Lett. 2012 Sep 21;586(19):3404-9. doi: 10.1016/j.febslet.2012.07.054. Epub 2012 Aug 7.


In vitro RNase and nucleic acid binding activities implicate coilin in U snRNA processing.

Broome HJ, Hebert MD.

PLoS One. 2012;7(4):e36300. doi: 10.1371/journal.pone.0036300. Epub 2012 Apr 27.


Coilin phosphomutants disrupt Cajal body formation, reduce cell proliferation and produce a distinct coilin degradation product.

Carrero ZI, Velma V, Douglas HE, Hebert MD.

PLoS One. 2011;6(10):e25743. doi: 10.1371/journal.pone.0025743. Epub 2011 Oct 3.


Coilin participates in the suppression of RNA polymerase I in response to cisplatin-induced DNA damage.

Gilder AS, Do PM, Carrero ZI, Cosman AM, Broome HJ, Velma V, Martinez LA, Hebert MD.

Mol Biol Cell. 2011 Apr;22(7):1070-9. doi: 10.1091/mbc.E10-08-0731. Epub 2011 Feb 2.


Coilin interacts with Ku proteins and inhibits in vitro non-homologous DNA end joining.

Velma V, Carrero ZI, Cosman AM, Hebert MD.

FEBS Lett. 2010 Dec 1;584(23):4735-9. doi: 10.1016/j.febslet.2010.11.004. Epub 2010 Nov 9.


Phosphorylation and the Cajal body: modification in search of function.

Hebert MD.

Arch Biochem Biophys. 2010 Apr 15;496(2):69-76. doi: 10.1016/ Epub 2010 Mar 1. Review.


A thermally targeted peptide inhibitor of symmetrical dimethylation inhibits cancer-cell proliferation.

Bidwell GL 3rd, Whittom AA, Thomas E, Lyons D, Hebert MD, Raucher D.

Peptides. 2010 May;31(5):834-41. doi: 10.1016/j.peptides.2010.02.007. Epub 2010 Feb 16.


Coilin phosphorylation mediates interaction with SMN and SmB'.

Toyota CG, Davis MD, Cosman AM, Hebert MD.

Chromosoma. 2010 Apr;119(2):205-15. doi: 10.1007/s00412-009-0249-x. Epub 2009 Dec 8.


Cajal-body formation correlates with differential coilin phosphorylation in primary and transformed cell lines.

Hearst SM, Gilder AS, Negi SS, Davis MD, George EM, Whittom AA, Toyota CG, Husedzinovic A, Gruss OJ, Hebert MD.

J Cell Sci. 2009 Jun 1;122(Pt 11):1872-81. doi: 10.1242/jcs.044040. Epub 2009 May 12.


Coilin levels and modifications influence artificial reporter splicing.

Whittom AA, Xu H, Hebert MD.

Cell Mol Life Sci. 2008 Apr;65(7-8):1256-71. doi: 10.1007/s00018-008-7587-3.


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