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Items: 1 to 20 of 24


Diet-induced obesity leads to pro-inflammatory alterations to the vitreous humour of the eye in a rat model.

Collins KH, Herzog W, Reimer RA, Reno CR, Heard BJ, Hart DA.

Inflamm Res. 2018 Feb;67(2):139-146. doi: 10.1007/s00011-017-1102-y. Epub 2017 Oct 26.


Relationship between increased in vivo meniscal loads and abnormal tibiofemoral surface alignment in ACL deficient sheep is varied.

Beveridge JE, Atarod M, Heard BJ, O'Brien EEJ, Frank CB, Shrive NG.

J Biomech. 2016 Dec 8;49(16):3824-3832. doi: 10.1016/j.jbiomech.2016.10.017. Epub 2016 Oct 20.


Analysis of change in gait in the ovine stifle: normal, injured, and anterior cruciate ligament reconstructed.

Heard BJ, Beveridge JE, Atarod M, O'Brien EJ, Rolian C, Frank CB, Hart DA, Shrive NG.

BMC Musculoskelet Disord. 2017 May 23;18(1):212. doi: 10.1186/s12891-017-1576-3.


Location and gene-specific effects of methylprednisolone acetate on mitigating IL1β-induced inflammation in mature ovine explant knee tissue.

Barton KI, Heard BJ, Chung M, Sevick JL, Martin CR, Achari Y, Frank CB, Shrive NG, Hart DA.

Inflamm Res. 2017 Mar;66(3):239-248. doi: 10.1007/s00011-016-1009-z. Epub 2016 Nov 16.


Use of pre-clinical surgically induced models to understand biomechanical and biological consequences of PTOA development.

Barton KI, Shekarforoush M, Heard BJ, Sevick JL, Vakil P, Atarod M, Martin R, Achari Y, Hart DA, Frank CB, Shrive NG.

J Orthop Res. 2017 Mar;35(3):454-465. doi: 10.1002/jor.23322. Epub 2017 Mar 2. Review.


The infrapatellar fat pad is affected by injury induced inflammation in the rabbit knee: use of dexamethasone to mitigate damage.

Heard BJ, Solbak NM, Chung M, Achari Y, Shrive NG, Frank CB, Hart DA.

Inflamm Res. 2016 Jun;65(6):459-70. doi: 10.1007/s00011-016-0928-z. Epub 2016 Feb 22.


Ligament and meniscus loading in the ovine stifle joint during normal gait.

Rosvold JM, Atarod M, Heard BJ, O'Brien EJ, Frank CB, Shrive NG.

Knee. 2016 Jan;23(1):70-7. doi: 10.1016/j.knee.2015.09.013. Epub 2016 Jan 4.


Single intra-articular dexamethasone injection immediately post-surgery in a rabbit model mitigates early inflammatory responses and post-traumatic osteoarthritis-like alterations.

Heard BJ, Barton KI, Chung M, Achari Y, Shrive NG, Frank CB, Hart DA.

J Orthop Res. 2015 Dec;33(12):1826-34. doi: 10.1002/jor.22972. Epub 2015 Jul 7.


Alterations in Hoffa's fat pad induced by an inflammatory response following idealized anterior cruciate ligament surgery.

Solbak NM, Heard BJ, Achari Y, Chung M, Shrive NG, Frank CB, Hart DA.

Inflamm Res. 2015 Aug;64(8):615-26. doi: 10.1007/s00011-015-0840-y. Epub 2015 Jun 20.


Metabolic profiling of synovial fluid in a unilateral ovine model of anterior cruciate ligament reconstruction of the knee suggests biomarkers for early osteoarthritis.

Mickiewicz B, Heard BJ, Chau JK, Chung M, Hart DA, Shrive NG, Frank CB, Vogel HJ.

J Orthop Res. 2015 Jan;33(1):71-7. doi: 10.1002/jor.22743. Epub 2014 Oct 4.


A new measure of tibiofemoral subchondral bone interactions that correlates with early cartilage damage in injured sheep.

Beveridge JE, Heard BJ, Brown JJ, Shrive NG, Frank CB.

J Orthop Res. 2014 Oct;32(10):1371-80. doi: 10.1002/jor.22685. Epub 2014 Jul 11.


A computational method to differentiate normal individuals, osteoarthritis and rheumatoid arthritis patients using serum biomarkers.

Heard BJ, Rosvold JM, Fritzler MJ, El-Gabalawy H, Wiley JP, Krawetz RJ.

J R Soc Interface. 2014 Aug 6;11(97):20140428. doi: 10.1098/rsif.2014.0428.


Changes of early post-traumatic osteoarthritis in an ovine model of simulated ACL reconstruction are associated with transient acute post-injury synovial inflammation and tissue catabolism.

Heard BJ, Solbak NM, Achari Y, Chung M, Hart DA, Shrive NG, Frank CB.

Osteoarthritis Cartilage. 2013 Dec;21(12):1942-9. doi: 10.1016/j.joca.2013.08.019. Epub 2013 Sep 5.


Monocyte chemotactic protein-1 inhibits chondrogenesis of synovial mesenchymal progenitor cells: an in vitro study.

Harris Q, Seto J, O'Brien K, Lee PS, Kondo C, Heard BJ, Hart DA, Krawetz RJ.

Stem Cells. 2013 Oct;31(10):2253-65. doi: 10.1002/stem.1477.


Tibiofemoral centroid velocity correlates more consistently with cartilage damage than does contact path length in two ovine models of stifle injury.

Beveridge JE, Heard BJ, Shrive NG, Frank CB.

J Orthop Res. 2013 Nov;31(11):1745-56. doi: 10.1002/jor.22429. Epub 2013 Jul 6.


Intraarticular and systemic inflammatory profiles may identify patients with osteoarthritis.

Heard BJ, Fritzler MJ, Wiley JP, McAllister J, Martin L, El-Gabalawy H, Hart DA, Frank CB, Krawetz R.

J Rheumatol. 2013 Aug;40(8):1379-87. doi: 10.3899/jrheum.121204. Epub 2013 May 15.


Matrix metalloproteinase protein expression profiles cannot distinguish between normal and early osteoarthritic synovial fluid.

Heard BJ, Martin L, Rattner JB, Frank CB, Hart DA, Krawetz R.

BMC Musculoskelet Disord. 2012 Jul 23;13:126. doi: 10.1186/1471-2474-13-126.


Osteoarthritis develops in the operated joint of an ovine model following ACL reconstruction with immediate anatomic reattachment of the native ACL.

O'Brien EJ, Beveridge JE, Huebner KD, Heard BJ, Tapper JE, Shrive NG, Frank CB.

J Orthop Res. 2013 Jan;31(1):35-43. doi: 10.1002/jor.22187. Epub 2012 Jul 13.


Investigating the potential value of individual parameters of histological grading systems in a sheep model of cartilage damage: the Modified Mankin method.

Moody HR, Heard BJ, Frank CB, Shrive NG, Oloyede AO.

J Anat. 2012 Jul;221(1):47-54. doi: 10.1111/j.1469-7580.2012.01513.x. Epub 2012 May 17.


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