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Items: 1 to 20 of 288

1.

Exploring PTDH-P450BM3 variants for the synthesis of drug metabolites.

Beyer N, Kulig JK, Fraaije MW, Hayes MA, Janssen D.

Chembiochem. 2017 Nov 27. doi: 10.1002/cbic.201700470. [Epub ahead of print]

PMID:
29181885
2.

Biofluid pretreatment using gradient insulator-based dielectrophoresis: separating cells from biomarkers.

Ding J, Woolley C, Hayes MA.

Anal Bioanal Chem. 2017 Nov;409(27):6405-6414. doi: 10.1007/s00216-017-0582-5. Epub 2017 Aug 29.

PMID:
28852806
3.

Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axis.

Nilsson A, Peric A, Strimfors M, Goodwin RJA, Hayes MA, Andrén PE, Hilgendorf C.

Sci Rep. 2017 Jul 25;7(1):6352. doi: 10.1038/s41598-017-06583-4.

4.

Simulated bat populations erode when exposed to climate change projections for western North America.

Hayes MA, Adams RA.

PLoS One. 2017 Jul 7;12(7):e0180693. doi: 10.1371/journal.pone.0180693. eCollection 2017.

5.

Saccharin Aza Bioisosteres-Synthesis and Preclinical Property Comparisons.

Chen Y, Aurell CJ, Pettersen A, Lewis RJ, Hayes MA, Lepistö M, Jonson AC, Leek H, Thunberg L.

ACS Med Chem Lett. 2017 May 1;8(6):672-677. doi: 10.1021/acsmedchemlett.7b00137. eCollection 2017 Jun 8.

PMID:
28626531
6.

Oxetane Substrates of Human Microsomal Epoxide Hydrolase.

Toselli F, Fredenwall M, Svensson P, Li XQ, Johansson A, Weidolf L, Hayes MA.

Drug Metab Dispos. 2017 Aug;45(8):966-973. doi: 10.1124/dmd.117.076489. Epub 2017 Jun 9.

PMID:
28600384
7.

Dynamics of sediment carbon stocks across intertidal wetland habitats of Moreton Bay, Australia.

Hayes MA, Jesse A, Hawke B, Baldock J, Tabet B, Lockington D, Lovelock CE.

Glob Chang Biol. 2017 Oct;23(10):4222-4234. doi: 10.1111/gcb.13722. Epub 2017 May 16.

PMID:
28407457
8.

Refinement of insulator-based dielectrophoresis.

Crowther CV, Hayes MA.

Analyst. 2017 May 2;142(9):1608-1618. doi: 10.1039/c6an02509a.

PMID:
28394391
9.

Synthesis of 1β-hydroxydeoxycholic acid in H-2 and unlabeled forms.

Hayes MA, Roberts I, Grönberg G, Lv K, Lin B, Bergare J, Elmore CS.

J Labelled Comp Radiopharm. 2017 Apr;60(4):221-229. doi: 10.1002/jlcr.3495. Epub 2017 Mar 20.

PMID:
28183147
10.

Endothelial protein C receptor-dependent antichemotactic effects of canine protein C.

Wong VM, Côté O, Bienzle D, Hayes MA, Wood RD.

Am J Vet Res. 2017 Feb;78(2):186-194. doi: 10.2460/ajvr.78.2.186.

PMID:
28140640
11.

The self-sufficient P450 RhF expressed in a whole cell system selectively catalyses the 5-hydroxylation of diclofenac.

Klenk JM, Nebel BA, Porter JL, Kulig JK, Hussain SA, Richter SM, Tavanti M, Turner NJ, Hayes MA, Hauer B, Flitsch SL.

Biotechnol J. 2017 Mar;12(3). doi: 10.1002/biot.201600520. Epub 2017 Feb 8.

PMID:
28098428
12.

P450BM3 fused to phosphite dehydrogenase allows phosphite-driven selective oxidations.

Beyer N, Kulig JK, Bartsch A, Hayes MA, Janssen DB, Fraaije MW.

Appl Microbiol Biotechnol. 2017 Mar;101(6):2319-2331. doi: 10.1007/s00253-016-7993-7. Epub 2016 Nov 29.

13.

Sinusoidal endothelial cell and hepatic stellate cell phenotype correlates with stage of fibrosis in chronic liver disease in dogs.

Vince AR, Hayes MA, Jefferson BJ, Stalker MJ.

J Vet Diagn Invest. 2016 Sep;28(5):498-505. doi: 10.1177/1040638716658499. Epub 2016 Jul 16.

PMID:
27423735
14.

CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity.

Hayes MA, Li XQ, Grönberg G, Diczfalusy U, Andersson TB.

Drug Metab Dispos. 2016 Sep;44(9):1480-9. doi: 10.1124/dmd.116.070805. Epub 2016 Jul 11.

15.

Discovery of a Novel Microsomal Epoxide Hydrolase-Catalyzed Hydration of a Spiro Oxetane.

Li XQ, Hayes MA, Grönberg G, Berggren K, Castagnoli N Jr, Weidolf L.

Drug Metab Dispos. 2016 Aug;44(8):1341-8. doi: 10.1124/dmd.116.071142. Epub 2016 Jun 2.

16.

Concentration of Sindbis virus with optimized gradient insulator-based dielectrophoresis.

Ding J, Lawrence RM, Jones PV, Hogue BG, Hayes MA.

Analyst. 2016 Mar 21;141(6):1997-2008. doi: 10.1039/c5an02430g.

PMID:
26878279
17.

Database Extraction of Metabolite Information of Drug Candidates: Analysis of 27 AstraZeneca Compounds with Human Absorption, Distribution, Metabolism, and Excretion Data.

Iegre J, Hayes MA, Thompson RA, Weidolf L, Isin EM.

Drug Metab Dispos. 2016 May;44(5):732-40. doi: 10.1124/dmd.115.067850. Epub 2016 Feb 11.

18.

Discovery of (3-(4-(2-Oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy)azetidin-1-yl)(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methanone (AZD1979), a Melanin Concentrating Hormone Receptor 1 (MCHr1) Antagonist with Favorable Physicochemical Properties.

Johansson A, Löfberg C, Antonsson M, von Unge S, Hayes MA, Judkins R, Ploj K, Benthem L, Lindén D, Brodin P, Wennerberg M, Fredenwall M, Li L, Persson J, Bergman R, Pettersen A, Gennemark P, Hogner A.

J Med Chem. 2016 Mar 24;59(6):2497-511. doi: 10.1021/acs.jmedchem.5b01654. Epub 2016 Feb 5.

PMID:
26741166
19.

Correction: Biophysical separation of Staphylococcus epidermidis strains based on antibiotic resistance.

Jones PV, Huey Hilton S, Davis PE, Yanashima R, McLemore R, McLaren A, Hayes MA.

Analyst. 2016 Jan 7;141(1):352. doi: 10.1039/c5an90100f. Epub 2015 Dec 2.

PMID:
26626370
20.

Sensitive Detection of Cardiac Biomarkers Using a Magnetic Microbead Immunoassay.

Woolley CF, Hayes MA.

Anal Methods. 2015 Oct 21;7(20):8632-8639. Epub 2015 Aug 20.

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