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Items: 1 to 20 of 27


Severity of bias of a simple estimator of the causal odds ratio in Mendelian randomization studies.

Harbord RM, Didelez V, Palmer TM, Meng S, Sterne JA, Sheehan NA.

Stat Med. 2013 Mar 30;32(7):1246-58. doi: 10.1002/sim.5659. Epub 2012 Oct 18.


Is MRI better than CT for detecting a vascular component to dementia? A systematic review and meta-analysis.

Beynon R, Sterne JA, Wilcock G, Likeman M, Harbord RM, Astin M, Burke M, Bessell A, Ben-Shlomo Y, Hawkins J, Hollingworth W, Whiting P.

BMC Neurol. 2012 Jun 6;12:33. doi: 10.1186/1471-2377-12-33. Review.


Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials.

Sterne JA, Sutton AJ, Ioannidis JP, Terrin N, Jones DR, Lau J, Carpenter J, Rücker G, Harbord RM, Schmid CH, Tetzlaff J, Deeks JJ, Peters J, Macaskill P, Schwarzer G, Duval S, Altman DG, Moher D, Higgins JP.

BMJ. 2011 Jul 22;343:d4002. doi: 10.1136/bmj.d4002. No abstract available.


Commentary on 'Multivariate meta-analysis: potential and promise'.

Harbord RM.

Stat Med. 2011 Sep 10;30(20):2507-8; discussion 2509-10. doi: 10.1002/sim.4278. Epub 2011 Jun 27. No abstract available.


Instrumental variable estimation of causal risk ratios and causal odds ratios in Mendelian randomization analyses.

Palmer TM, Sterne JA, Harbord RM, Lawlor DA, Sheehan NA, Meng S, Granell R, Smith GD, Didelez V.

Am J Epidemiol. 2011 Jun 15;173(12):1392-403. doi: 10.1093/aje/kwr026. Epub 2011 May 9.


Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.

De Silva NM, Freathy RM, Palmer TM, Donnelly LA, Luan J, Gaunt T, Langenberg C, Weedon MN, Shields B, Knight BA, Ward KJ, Sandhu MS, Harbord RM, McCarthy MI, Smith GD, Ebrahim S, Hattersley AT, Wareham N, Lawlor DA, Morris AD, Palmer CN, Frayling TM.

Diabetes. 2011 Mar;60(3):1008-18. doi: 10.2337/db10-1317. Epub 2011 Jan 31.


Using multiple genetic variants as instrumental variables for modifiable risk factors.

Palmer TM, Lawlor DA, Harbord RM, Sheehan NA, Tobias JH, Timpson NJ, Davey Smith G, Sterne JA.

Stat Methods Med Res. 2012 Jun;21(3):223-42. doi: 10.1177/0962280210394459. Epub 2011 Jan 7.


Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults.

Lawlor DA, Harbord RM, Tybjaerg-Hansen A, Palmer TM, Zacho J, Benn M, Timpson NJ, Smith GD, Nordestgaard BG.

J Intern Med. 2011 May;269(5):525-37. doi: 10.1111/j.1365-2796.2011.02343.x. Erratum in: J Intern Med. 2013 Apr;273(4):423.


C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization.

Timpson NJ, Nordestgaard BG, Harbord RM, Zacho J, Frayling TM, Tybjærg-Hansen A, Smith GD.

Int J Obes (Lond). 2011 Feb;35(2):300-8. doi: 10.1038/ijo.2010.137. Epub 2010 Aug 17.


Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants.

Timpson NJ, Forouhi NG, Brion MJ, Harbord RM, Cook DG, Johnson P, McConnachie A, Morris RW, Rodriguez S, Luan J, Ebrahim S, Padmanabhan S, Watt G, Bruckdorfer KR, Wareham NJ, Whincup PH, Chanock S, Sattar N, Lawlor DA, Davey Smith G.

Am J Clin Nutr. 2010 Aug;92(2):375-82. doi: 10.3945/ajcn.2010.29438. Epub 2010 Jun 2. Erratum in: Am J Clin Nutr. 2013 Jul;98(1):253-4.


Can lactase persistence genotype be used to reassess the relationship between renal cell carcinoma and milk drinking? Potentials and problems in the application of Mendelian randomization.

Timpson NJ, Brennan P, Gaborieau V, Moore L, Zaridze D, Matveev V, Szeszenia-Dabrowska N, Lissowska J, Mates D, Bencko V, Foretova L, Janout V, Chow WH, Rothman N, Boffetta P, Harbord RM, Smith GD.

Cancer Epidemiol Biomarkers Prev. 2010 May;19(5):1341-8. doi: 10.1158/1055-9965.EPI-09-1019.


Thighs and heart disease. Thighs and thresholds.

Harbord RM, Sterne JA.

BMJ. 2009 Oct 21;339:b4246. doi: 10.1136/bmj.b4246. No abstract available.


Genetically elevated C-reactive protein and vascular disease.

Harbord RM, Lawlor DA, Smith GD.

N Engl J Med. 2009 Feb 26;360(9):933; author reply 934-5. doi: 10.1056/NEJMc082413. No abstract available.


An empirical comparison of methods for meta-analysis of diagnostic accuracy showed hierarchical models are necessary.

Harbord RM, Whiting P, Sterne JA, Egger M, Deeks JJ, Shang A, Bachmann LM.

J Clin Epidemiol. 2008 Nov;61(11):1095-103. doi: 10.1016/j.jclinepi.2007.09.013. Review.


The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants.

Lawlor DA, Harbord RM, Timpson NJ, Lowe GD, Rumley A, Gaunt TR, Baker I, Yarnell JW, Kivimäki M, Kumari M, Norman PE, Jamrozik K, Hankey GJ, Almeida OP, Flicker L, Warrington N, Marmot MG, Ben-Shlomo Y, Palmer LJ, Day IN, Ebrahim S, Smith GD.

PLoS One. 2008 Aug 20;3(8):e3011. doi: 10.1371/journal.pone.0003011.


How much of the data published in observational studies of the association between diet and prostate or bladder cancer is usable for meta-analysis?

Bekkering GE, Harris RJ, Thomas S, Mayer AM, Beynon R, Ness AR, Harbord RM, Bain C, Smith GD, Sterne JA.

Am J Epidemiol. 2008 May 1;167(9):1017-26. doi: 10.1093/aje/kwn005. Epub 2008 Apr 10. Review. Erratum in: Am J Epidemiol. 2009 Aug 15;170(4):536.


Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable.

Lawlor DA, Timpson NJ, Harbord RM, Leary S, Ness A, McCarthy MI, Frayling TM, Hattersley AT, Smith GD.

PLoS Med. 2008 Mar 11;5(3):e33. doi: 10.1371/journal.pmed.0050033.


Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach.

Chen L, Smith GD, Harbord RM, Lewis SJ.

PLoS Med. 2008 Mar 4;5(3):e52. doi: 10.1371/journal.pmed.0050052. Review.


Mendelian randomization: using genes as instruments for making causal inferences in epidemiology.

Lawlor DA, Harbord RM, Sterne JA, Timpson N, Davey Smith G.

Stat Med. 2008 Apr 15;27(8):1133-63.


Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk.

Lewis SJ, Harbord RM, Harris R, Smith GD.

J Natl Cancer Inst. 2006 Nov 15;98(22):1607-22.


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