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Items: 1 to 20 of 91

1.

An effective and efficient method of transfecting primary human chondrocytes in suspension.

Makki MS, Akhtar N, Haqqi TM.

Anal Biochem. 2017 Jun 1;526:29-32. doi: 10.1016/j.ab.2017.03.009. Epub 2017 Mar 14.

PMID:
28315317
2.

A Polyphenol-rich Pomegranate Fruit Extract Suppresses NF-κB and IL-6 Expression by Blocking the Activation of IKKβ and NIK in Primary Human Chondrocytes.

Haseeb A, Khan NM, Ashruf OS, Haqqi TM.

Phytother Res. 2017 Mar 9. doi: 10.1002/ptr.5799. [Epub ahead of print]

PMID:
28276100
4.

Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes.

Khan NM, Haseeb A, Ansari MY, Devarapalli P, Haynie S, Haqqi TM.

Free Radic Biol Med. 2017 May;106:288-301. doi: 10.1016/j.freeradbiomed.2017.02.041. Epub 2017 Feb 22.

PMID:
28237856
5.

Inhibition of cartilage degradation and suppression of PGE2 and MMPs expression by pomegranate fruit extract in a model of posttraumatic osteoarthritis.

Akhtar N, Khan NM, Ashruf OS, Haqqi TM.

Nutrition. 2017 Jan;33:1-13. doi: 10.1016/j.nut.2016.08.004. Epub 2016 Sep 2.

PMID:
27908544
6.

Sucrose, But Not Glucose, Blocks IL1-β-Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway.

Khan NM, Ansari MY, Haqqi TM.

J Cell Biochem. 2017 Mar;118(3):629-639. doi: 10.1002/jcb.25750. Epub 2016 Oct 12.

PMID:
27669541
7.

Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1β-Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte.

Makki MS, Haqqi TM.

Am J Pathol. 2016 Oct;186(10):2701-8. doi: 10.1016/j.ajpath.2016.06.010. Epub 2016 Aug 20.

PMID:
27555113
8.

Histone deacetylase inhibitor vorinostat (SAHA, MK0683) perturb miR-9-MCPIP1 axis to block IL-1β-induced IL-6 expression in human OA chondrocytes.

Makki MS, Haqqi TM.

Connect Tissue Res. 2017 Jan;58(1):64-75. doi: 10.1080/03008207.2016.1211113. Epub 2016 Jul 12.

PMID:
27404795
9.

The Role of MicroRNAs and Their Targets in Osteoarthritis.

Sondag GR, Haqqi TM.

Curr Rheumatol Rep. 2016 Aug;18(8):56. doi: 10.1007/s11926-016-0604-x. Review.

PMID:
27402113
10.
11.

Harpagoside suppresses IL-6 expression in primary human osteoarthritis chondrocytes.

Haseeb A, Ansari MY, Haqqi TM.

J Orthop Res. 2017 Feb;35(2):311-320. doi: 10.1002/jor.23262. Epub 2016 May 4.

PMID:
27082319
12.

miR-139 modulates MCPIP1/IL-6 expression and induces apoptosis in human OA chondrocytes.

Makki MS, Haqqi TM.

Exp Mol Med. 2015 Oct 9;47:e189. doi: 10.1038/emm.2015.66.

14.

MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes.

Akhtar N, Makki MS, Haqqi TM.

Arthritis Rheumatol. 2015 Feb;67(2):423-34. doi: 10.1002/art.38952.

15.
16.

Protective effects of C-type natriuretic peptide on linear growth and articular cartilage integrity in a mouse model of inflammatory arthritis.

Bükülmez H, Khan F, Bartels CF, Murakami S, Ortiz-Lopez A, Sattar A, Haqqi TM, Warman ML.

Arthritis Rheumatol. 2014 Jan;66(1):78-89. doi: 10.1002/art.38199.

17.

Delphinidin inhibits IL-1β-induced activation of NF-κB by modulating the phosphorylation of IRAK-1(Ser376) in human articular chondrocytes.

Haseeb A, Chen D, Haqqi TM.

Rheumatology (Oxford). 2013 Jun;52(6):998-1008. doi: 10.1093/rheumatology/kes363. Epub 2013 Feb 7.

18.

Immunopathogenesis of osteoarthritis.

Haseeb A, Haqqi TM.

Clin Immunol. 2013 Mar;146(3):185-96. doi: 10.1016/j.clim.2012.12.011. Epub 2013 Jan 6. Review.

19.
20.

Current nutraceuticals in the management of osteoarthritis: a review.

Akhtar N, Haqqi TM.

Ther Adv Musculoskelet Dis. 2012 Jun;4(3):181-207. doi: 10.1177/1759720X11436238.

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