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Items: 1 to 20 of 174

1.

Progression of Structural Brain Changes in Patients With Chronic Pancreatitis and Its Association to Chronic Pain: A 7-Year Longitudinal Follow-up Study.

Muthulingam J, Olesen SS, Hansen TM, Seminowicz DA, Burrowes S, Drewes AM, Frøkjær JB.

Pancreas. 2018 Nov/Dec;47(10):1267-1276. doi: 10.1097/MPA.0000000000001151.

PMID:
30211804
2.

Prehospital treatment of patients with acute intracranial pathology: adherence to guidelines and blood pressure recommendations by the Danish Air Ambulance.

Juelsgaard J, Rognås L, Knudsen L, Hansen TM, Rasmussen M.

Scand J Trauma Resusc Emerg Med. 2018 Aug 22;26(1):68. doi: 10.1186/s13049-018-0534-x.

3.

Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Kluge AF, Patane MA, Van Drie JH, Wang C, McElligott D, Kesicki EA, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD.

Nature. 2018 Jun;558(7710):E1. doi: 10.1038/s41586-018-0111-5.

PMID:
29769713
4.

Differential effects of oxycodone and venlafaxine on resting state functional connectivity-A randomized placebo-controlled magnetic resonance imaging study.

Hansen TM, Lelic D, Olesen AE, Drewes AM, Frøkjaer JB.

CNS Neurosci Ther. 2018 Feb 21. doi: 10.1111/cns.12827. [Epub ahead of print]

PMID:
29468854
5.

Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases.

Michaelides MR, Kluge A, Patane M, Van Drie JH, Wang C, Hansen TM, Risi RM, Mantei R, Hertel C, Karukurichi K, Nesterov A, McElligott D, de Vries P, Langston JW, Cole PA, Marmorstein R, Liu H, Lasko L, Bromberg KD, Lai A, Kesicki EA.

ACS Med Chem Lett. 2017 Dec 13;9(1):28-33. doi: 10.1021/acsmedchemlett.7b00395. eCollection 2018 Jan 11.

6.

Predictive value of routine point-of-care cardiac troponin T measurement for prehospital diagnosis and risk-stratification in patients with suspected acute myocardial infarction.

Rasmussen MB, Stengaard C, Sørensen JT, Riddervold IS, Hansen TM, Giebner M, Rasmussen CH, Bøtker HE, Terkelsen CJ.

Eur Heart J Acute Cardiovasc Care. 2017 Dec 1:2048872617745893. doi: 10.1177/2048872617745893. [Epub ahead of print]

PMID:
29199427
7.

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Van Drie JH, McElligott D, Kesicki E, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD.

Nature. 2017 Oct 5;550(7674):128-132. doi: 10.1038/nature24028. Epub 2017 Sep 27. Erratum in: Nature. 2018 May 16;:.

8.

Objective methods for the assessment of the spinal and supraspinal effects of opioids.

Fischer IW, Hansen TM, Lelic D, Brokjaer A, Frøkjær J, Christrup LL, Olesen AE.

Scand J Pain. 2017 Jan;14:15-24. doi: 10.1016/j.sjpain.2016.10.001. Epub 2016 Nov 1. Review.

PMID:
28850426
9.

Treatment Minimization in Older Patients With Early-Stage Breast Cancer.

Hansen TM, Zellars RC.

Cancer J. 2017 Jul/Aug;23(4):231-237. doi: 10.1097/PPO.0000000000000272. Review.

PMID:
28731946
10.

Microstructural white matter brain abnormalities in patients with idiopathic fecal incontinence.

Muthulingam J, Haas S, Hansen TM, Laurberg S, Lundby L, Jørgensen HS, Drewes AM, Krogh K, Frøkjaer JB.

Neurogastroenterol Motil. 2018 Jan;30(1). doi: 10.1111/nmo.13164. Epub 2017 Jul 21.

PMID:
28730720
11.

Characterization of cortical source generators based on electroencephalography during tonic pain.

Hansen TM, Mark EB, Olesen SS, Gram M, Frøkjær JB, Drewes AM.

J Pain Res. 2017 Jun 7;10:1401-1409. doi: 10.2147/JPR.S132909. eCollection 2017.

12.

The effects of analgesics on central processing of tonic pain: A cross-over placebo controlled study.

Lelic D, Hansen TM, Mark EB, Olesen AE, Drewes AM.

Neuropharmacology. 2017 Sep 1;123:455-464. doi: 10.1016/j.neuropharm.2017.06.022. Epub 2017 Jun 22.

PMID:
28648913
13.

SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT).

Curtin ML, Heyman HR, Clark RF, Sorensen BK, Doherty GA, Hansen TM, Frey RR, Sarris KA, Aguirre AL, Shrestha A, Tu N, Woller K, Pliushchev MA, Sweis RF, Cheng M, Wilsbacher JL, Kovar PJ, Guo J, Cheng D, Longenecker KL, Raich D, Korepanova AV, Soni NB, Algire MA, Richardson PL, Marin VL, Badagnani I, Vasudevan A, Buchanan FG, Maag D, Chiang GG, Tse C, Michaelides MR.

Bioorg Med Chem Lett. 2017 Aug 1;27(15):3317-3325. doi: 10.1016/j.bmcl.2017.06.018. Epub 2017 Jun 14.

PMID:
28610984
14.

Prehospital triage of patients suffering severe dyspnoea using N-terminal pro-brain natriuretic peptide, the PreBNP trial: a randomised controlled clinical trial.

Bøtker MT, Jørgensen MT, Stengaard C, Seidenfaden SC, Tarpgaard M, Granfeldt A, Mortensen TØ, Grøfte T, Friesgaard KD, Mærkedahl R, Pedersen AB, Lundorff S, Hansen TM, Kirkegaard H, Christensen EF, Terkelsen CJ.

Eur Heart J Acute Cardiovasc Care. 2018 Jun;7(4):302-310. doi: 10.1177/2048872617709985. Epub 2017 May 11.

PMID:
28492084
15.

Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors.

Wilsbacher JL, Cheng M, Cheng D, Trammell SAJ, Shi Y, Guo J, Koeniger SL, Kovar PJ, He Y, Selvaraju S, Heyman HR, Sorensen BK, Clark RF, Hansen TM, Longenecker KL, Raich D, Korepanova AV, Cepa S, Towne DL, Abraham VC, Tang H, Richardson PL, McLoughlin SM, Badagnani I, Curtin ML, Michaelides MR, Maag D, Buchanan FG, Chiang GG, Gao W, Rosenberg SH, Brenner C, Tse C.

Mol Cancer Ther. 2017 Jul;16(7):1236-1245. doi: 10.1158/1535-7163.MCT-16-0819. Epub 2017 May 3.

16.

Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors.

Wang L, Pratt JK, Soltwedel T, Sheppard GS, Fidanze SD, Liu D, Hasvold LA, Mantei RA, Holms JH, McClellan WJ, Wendt MD, Wada C, Frey R, Hansen TM, Hubbard R, Park CH, Li L, Magoc TJ, Albert DH, Lin X, Warder SE, Kovar P, Huang X, Wilcox D, Wang R, Rajaraman G, Petros AM, Hutchins CW, Panchal SC, Sun C, Elmore SW, Shen Y, Kati WM, McDaniel KF.

J Med Chem. 2017 May 11;60(9):3828-3850. doi: 10.1021/acs.jmedchem.7b00017. Epub 2017 Apr 21.

PMID:
28368119
17.

Calculating the 30-day Survival Rate in Acute Myocardial Infarction: Should we Use the Treatment Chain or the Hospital Catchment Model?

Norum J, Hansen TM, Hovland A, Balteskard L, Haug B, Olsen F, Trovik T.

Heart Int. 2017 Feb 12;12(1). pii: heartint.5000238. doi: 10.5301/heartint.5000238. eCollection 2017 Jan-Dec.

18.

Cortical and spinal assessment - a comparative study using encephalography and the nociceptive withdrawal reflex.

Fischer IW, Gram M, Hansen TM, Brokjaer A, Graversen C, Malver LP, Mørch CD, Christrup LL, Drewes AM, Olesen AE.

J Pharmacol Toxicol Methods. 2017 Mar - Apr;84:37-43. doi: 10.1016/j.vascn.2016.10.008. Epub 2016 Oct 29.

PMID:
27989852
19.

Extracorporeal cardiopulmonary resuscitation after out-of-hospital cardiac arrest in a Danish health region.

Fjølner J, Greisen J, Jørgensen MR, Terkelsen CJ, Ilkjaer LB, Hansen TM, Eiskjaer H, Christensen S, Gjedsted J.

Acta Anaesthesiol Scand. 2017 Feb;61(2):176-185. doi: 10.1111/aas.12843. Epub 2016 Dec 9.

PMID:
27935015
20.

Integrity of central nervous function in diabetes mellitus assessed by resting state EEG frequency analysis and source localization.

Frøkjær JB, Graversen C, Brock C, Khodayari-Rostamabad A, Olesen SS, Hansen TM, Søfteland E, Simrén M, Drewes AM.

J Diabetes Complications. 2017 Feb;31(2):400-406. doi: 10.1016/j.jdiacomp.2016.11.003. Epub 2016 Nov 6.

PMID:
27884662

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