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Items: 1 to 20 of 165


Smad6 Methylation Represses NFκB Activation and Periodontal Inflammation.

Zhang T, Wu J, Ungvijanpunya N, Jackson-Weaver O, Gou Y, Feng J, Ho TV, Shen Y, Liu J, Richard S, Jin J, Hajishengallis G, Chai Y, Xu J.

J Dent Res. 2018 Feb 1:22034518755688. doi: 10.1177/0022034518755688. [Epub ahead of print]


Endothelial Cell-Specific Overexpression of Del-1 Drives Expansion of Haematopoietic Progenitor Cells in the Bone Marrow.

Chen LS, Kourtzelis I, Singh RP, Grossklaus S, Wielockx B, Hajishengallis G, Chavakis T, Mitroulis I.

Thromb Haemost. 2018 Feb 7. doi: 10.1055/s-0038-1624582. [Epub ahead of print] No abstract available.


Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity.

Mitroulis I, Ruppova K, Wang B, Chen LS, Grzybek M, Grinenko T, Eugster A, Troullinaki M, Palladini A, Kourtzelis I, Chatzigeorgiou A, Schlitzer A, Beyer M, Joosten LAB, Isermann B, Lesche M, Petzold A, Simons K, Henry I, Dahl A, Schultze JL, Wielockx B, Zamboni N, Mirtschink P, Coskun Ü, Hajishengallis G, Netea MG, Chavakis T.

Cell. 2018 Jan 11;172(1-2):147-161.e12. doi: 10.1016/j.cell.2017.11.034.


Novel mechanisms and functions of complement.

Hajishengallis G, Reis ES, Mastellos DC, Ricklin D, Lambris JD.

Nat Immunol. 2017 Nov 16;18(12):1288-1298. doi: 10.1038/ni.3858. Review.


Metabolic nuclear receptors in periodontal host-microbe interactions and inflammation.

Hajishengallis G, Lamont RJ.

Mol Oral Microbiol. 2017 Oct 5. doi: 10.1111/omi.12198. [Epub ahead of print] No abstract available.


Meeting report: The 12th European oral microbiology workshop (EOMW) in Stockholm, Sweden.

Belibasakis GN, Curtis MA, Hajishengallis G, Zaura E.

Virulence. 2018 Jan 1;9(1):64-69. doi: 10.1080/21505594.2017.1376147. Epub 2017 Nov 10. No abstract available.


Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates.

Kajikawa T, Briones RA, Resuello RRG, Tuplano JV, Reis ES, Hajishengallis E, Garcia CAG, Yancopoulou D, Lambris JD, Hajishengallis G.

Mol Ther Methods Clin Dev. 2017 Aug 18;6:207-215. doi: 10.1016/j.omtm.2017.08.001. eCollection 2017 Sep 15.


Porphyromonas gingivalis Stimulates TLR2-PI3K Signaling to Escape Immune Clearance and Induce Bone Resorption Independently of MyD88.

Makkawi H, Hoch S, Burns E, Hosur K, Hajishengallis G, Kirschning CJ, Nussbaum G.

Front Cell Infect Microbiol. 2017 Aug 8;7:359. doi: 10.3389/fcimb.2017.00359. eCollection 2017.


Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche.

Mitroulis I, Chen LS, Singh RP, Kourtzelis I, Economopoulou M, Kajikawa T, Troullinaki M, Ziogas A, Ruppova K, Hosur K, Maekawa T, Wang B, Subramanian P, Tonn T, Verginis P, von Bonin M, Wobus M, Bornhäuser M, Grinenko T, Di Scala M, Hidalgo A, Wielockx B, Hajishengallis G, Chavakis T.

J Clin Invest. 2017 Oct 2;127(10):3624-3639. doi: 10.1172/JCI92571. Epub 2017 Aug 28.


Endothelial cell-specific overexpression of developmental endothelial locus-1 does not influence atherosclerosis development in ApoE-/- mice.

Subramanian P, Prucnal M, Gercken B, Economopoulou M, Hajishengallis G, Chavakis T.

Thromb Haemost. 2017 Oct 5;117(10):2003-2005. doi: 10.1160/TH17-03-0160. Epub 2017 Aug 10. No abstract available.


Revisiting the Page & Schroeder model: the good, the bad and the unknowns in the periodontal host response 40 years later.

Hajishengallis G, Korostoff JM.

Periodontol 2000. 2017 Oct;75(1):116-151. doi: 10.1111/prd.12181. Review.


Porphyromonas gingivalis disturbs host-commensal homeostasis by changing complement function.

Olsen I, Lambris JD, Hajishengallis G.

J Oral Microbiol. 2017 Jun 30;9(1):1340085. doi: 10.1080/20002297.2017.1340085. eCollection 2017. Review.


Endogenous developmental endothelial locus-1 limits ischaemia-related angiogenesis by blocking inflammation.

Klotzsche-von Ameln A, Cremer S, Hoffmann J, Schuster P, Khedr S, Korovina I, Troullinaki M, Neuwirth A, Sprott D, Chatzigeorgiou A, Economopoulou M, Orlandi A, Hain A, Zeiher AM, Deussen A, Hajishengallis G, Dimmeler S, Chavakis T, Chavakis E.

Thromb Haemost. 2017 Jun 2;117(6):1150-1163. doi: 10.1160/TH16-05-0354. Epub 2017 Apr 27.


A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity.

Chung KJ, Chatzigeorgiou A, Economopoulou M, Garcia-Martin R, Alexaki VI, Mitroulis I, Nati M, Gebler J, Ziemssen T, Goelz SE, Phieler J, Lim JH, Karalis KP, Papayannopoulou T, Blüher M, Hajishengallis G, Chavakis T.

Nat Immunol. 2017 Jun;18(6):654-664. doi: 10.1038/ni.3728. Epub 2017 Apr 17.


Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1.

Moutsopoulos NM, Zerbe CS, Wild T, Dutzan N, Brenchley L, DiPasquale G, Uzel G, Axelrod KC, Lisco A, Notarangelo LD, Hajishengallis G, Notarangelo LD, Holland SM.

N Engl J Med. 2017 Mar 23;376(12):1141-1146. doi: 10.1056/NEJMoa1612197.


From leukocyte recruitment to resolution of inflammation: the cardinal role of integrins.

Kourtzelis I, Mitroulis I, von Renesse J, Hajishengallis G, Chavakis T.

J Leukoc Biol. 2017 Sep;102(3):677-683. doi: 10.1189/jlb.3MR0117-024R. Epub 2017 Mar 14. Review.


Milk fat globule epidermal growth factor 8 inhibits periodontitis in non-human primates and its gingival crevicular fluid levels can differentiate periodontal health from disease in humans.

Kajikawa T, Meshikhes F, Maekawa T, Hajishengallis E, Hosur KB, Abe T, Moss K, Chavakis T, Hajishengallis G.

J Clin Periodontol. 2017 May;44(5):472-483. doi: 10.1111/jcpe.12707. Epub 2017 Apr 12.


Expression and Regulation of Cholecystokinin Receptor in the Chicken's Immune Organs and Cells.

El-Kassas S, Odemuyiwa S, Hajishengallis G, Connell TD, Nashar TO.

J Clin Cell Immunol. 2016 Dec;7(6). pii: 471. doi: 10.4172/2155-9899.1000471. Epub 2016 Nov 25.


Dendritic Cell-Mediated Mechanisms Triggered by LT-IIa-B5, a Mucosal Adjuvant Derived from a Type II Heat-Labile Enterotoxin of Escherichia coli.

Lee CH, Hajishengallis G, Connell TD.

J Microbiol Biotechnol. 2017 Apr 28;27(4):709-717. doi: 10.4014/jmb.1611.11072.


Differential Expression and Roles of Secreted Frizzled-Related Protein 5 and the Wingless Homolog Wnt5a in Periodontitis.

Maekawa T, Kulwattanaporn P, Hosur K, Domon H, Oda M, Terao Y, Maeda T, Hajishengallis G.

J Dent Res. 2017 May;96(5):571-577. doi: 10.1177/0022034516687248. Epub 2017 Jan 17.


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