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Items: 1 to 20 of 148

1.

STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.

Woroniuk A, Porter A, White G, Newman DT, Diamantopoulou Z, Waring T, Rooney C, Strathdee D, Marston DJ, Hahn KM, Sansom OJ, Zech T, Malliri A.

Nat Commun. 2018 May 29;9(1):2124. doi: 10.1038/s41467-018-04404-4.

2.

An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration.

Tajadura-Ortega V, Garg R, Allen R, Owczarek C, Bright MD, Kean S, Mohd-Noor A, Grigoriadis A, Elston TC, Hahn KM, Ridley AJ.

BMC Biol. 2018 Mar 6;16(1):29. doi: 10.1186/s12915-018-0489-4.

3.

Light-Dependent Cytoplasmic Recruitment Enhances the Dynamic Range of a Nuclear Import Photoswitch.

Yumerefendi H, Wang H, Dickinson DJ, Lerner AM, Malkus P, Goldstein B, Hahn K, Kuhlman B.

Chembiochem. 2018 Feb 14. doi: 10.1002/cbic.201700681. [Epub ahead of print]

PMID:
29446199
4.

Local control of intracellular microtubule dynamics by EB1 photodissociation.

van Haren J, Charafeddine RA, Ettinger A, Wang H, Hahn KM, Wittmann T.

Nat Cell Biol. 2018 Mar;20(3):252-261. doi: 10.1038/s41556-017-0028-5. Epub 2018 Jan 29.

PMID:
29379139
5.

Discovery of long-range inhibitory signaling to ensure single axon formation.

Takano T, Wu M, Nakamuta S, Naoki H, Ishizawa N, Namba T, Watanabe T, Xu C, Hamaguchi T, Yura Y, Amano M, Hahn KM, Kaibuchi K.

Nat Commun. 2017 Jun 26;8(1):33. doi: 10.1038/s41467-017-00044-2.

6.

Spatial analysis of Cdc42 activity reveals a role for plasma membrane-associated Cdc42 in centrosome regulation.

Herrington KA, Trinh AL, Dang C, O'Shaughnessy E, Hahn KM, Gratton E, Digman MA, Sütterlin C.

Mol Biol Cell. 2017 Jul 15;28(15):2135-2145. doi: 10.1091/mbc.E16-09-0665. Epub 2017 May 24.

7.

Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains.

Ye F, Yang C, Kim J, MacNevin CJ, Hahn KM, Park D, Ginsberg MH, Kim C.

J Biol Chem. 2017 Jun 16;292(24):9858-9864. doi: 10.1074/jbc.C117.787309. Epub 2017 May 9.

8.

Engineering Pak1 Allosteric Switches.

Dagliyan O, Karginov AV, Yagishita S, Gale ME, Wang H, DerMardirossian C, Wells CM, Dokholyan NV, Kasai H, Hahn KM.

ACS Synth Biol. 2017 Jul 21;6(7):1257-1262. doi: 10.1021/acssynbio.6b00359. Epub 2017 Apr 6.

PMID:
28365983
9.

Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin.

Woodham EF, Paul NR, Tyrrell B, Spence HJ, Swaminathan K, Scribner MR, Giampazolias E, Hedley A, Clark W, Kage F, Marston DJ, Hahn KM, Tait SW, Larue L, Brakebusch CH, Insall RH, Machesky LM.

Curr Biol. 2017 Mar 6;27(5):624-637. doi: 10.1016/j.cub.2017.01.033. Epub 2017 Feb 23.

10.

Engineering extrinsic disorder to control protein activity in living cells.

Dagliyan O, Tarnawski M, Chu PH, Shirvanyants D, Schlichting I, Dokholyan NV, Hahn KM.

Science. 2016 Dec 16;354(6318):1441-1444.

11.

LOVTRAP: A Versatile Method to Control Protein Function with Light.

Wang H, Hahn KM.

Curr Protoc Cell Biol. 2016 Dec 1;73:21.10.1-21.10.14. doi: 10.1002/cpcb.12.

12.

PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front.

Nguyen TT, Park WS, Park BO, Kim CY, Oh Y, Kim JM, Choi H, Kyung T, Kim CH, Lee G, Hahn KM, Meyer T, Heo WD.

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10091-6. doi: 10.1073/pnas.1604720113. Epub 2016 Aug 23.

13.

FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions.

Hodgson L, Spiering D, Sabouri-Ghomi M, Dagliyan O, DerMardirossian C, Danuser G, Hahn KM.

Nat Chem Biol. 2016 Oct;12(10):802-809. doi: 10.1038/nchembio.2145. Epub 2016 Aug 8.

14.

LOVTRAP: an optogenetic system for photoinduced protein dissociation.

Wang H, Vilela M, Winkler A, Tarnawski M, Schlichting I, Yumerefendi H, Kuhlman B, Liu R, Danuser G, Hahn KM.

Nat Methods. 2016 Sep;13(9):755-8. doi: 10.1038/nmeth.3926. Epub 2016 Jul 18.

15.

Light-induced nuclear export reveals rapid dynamics of epigenetic modifications.

Yumerefendi H, Lerner AM, Zimmerman SP, Hahn K, Bear JE, Strahl BD, Kuhlman B.

Nat Chem Biol. 2016 Jun;12(6):399-401. doi: 10.1038/nchembio.2068. Epub 2016 Apr 18.

16.

A new method to measure complexity in binary or weighted networks and applications to functional connectivity in the human brain.

Hahn K, Massopust PR, Prigarin S.

BMC Bioinformatics. 2016 Feb 13;17:87. doi: 10.1186/s12859-016-0933-9.

17.

Ratiometric Imaging Using a Single Dye Enables Simultaneous Visualization of Rac1 and Cdc42 Activation.

MacNevin CJ, Toutchkine A, Marston DJ, Hsu CW, Tsygankov D, Li L, Liu B, Qi T, Nguyen DV, Hahn KM.

J Am Chem Soc. 2016 Mar 2;138(8):2571-5. doi: 10.1021/jacs.5b09764. Epub 2016 Feb 19.

18.

Characterization of an Engineered Src Kinase to Study Src Signaling and Biology.

Gentry LR, Karginov AV, Hahn KM, Der CJ.

Methods Mol Biol. 2016;1360:157-67. doi: 10.1007/978-1-4939-3073-9_12.

19.

Labelling and optical erasure of synaptic memory traces in the motor cortex.

Hayashi-Takagi A, Yagishita S, Nakamura M, Shirai F, Wu YI, Loshbaugh AL, Kuhlman B, Hahn KM, Kasai H.

Nature. 2015 Sep 17;525(7569):333-8. doi: 10.1038/nature15257. Epub 2015 Sep 9.

20.

An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A.

Yi JJ, Berrios J, Newbern JM, Snider WD, Philpot BD, Hahn KM, Zylka MJ.

Cell. 2015 Aug 13;162(4):795-807. doi: 10.1016/j.cell.2015.06.045. Epub 2015 Aug 6.

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