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Items: 1 to 20 of 394

1.

Resisting fatal attraction: a glioma oncometabolite prevents CD8+ T cell recruitment.

Lucca LE, Hafler DA.

J Clin Invest. 2017 Apr 3;127(4):1218-1220. doi: 10.1172/JCI93565. Epub 2017 Mar 20.

2.

Co-inhibitory blockade while preserving tolerance: checkpoint inhibitors for glioblastoma.

Lucca LE, Hafler DA.

Immunol Rev. 2017 Mar;276(1):9-25. doi: 10.1111/imr.12529. Review.

PMID:
28258696
3.

Solving Immunology?

Vodovotz Y, Xia A, Read EL, Bassaganya-Riera J, Hafler DA, Sontag E, Wang J, Tsang JS, Day JD, Kleinstein SH, Butte AJ, Altman MC, Hammond R, Sealfon SC.

Trends Immunol. 2017 Feb;38(2):116-127. doi: 10.1016/j.it.2016.11.006. Epub 2016 Dec 13. Review.

PMID:
27986392
4.

TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.

Taylor RA, Chang CF, Goods BA, Hammond MD, Mac Grory B, Ai Y, Steinschneider AF, Renfroe SC, Askenase MH, McCullough LD, Kasner SE, Mullen MT, Hafler DA, Love JC, Sansing LH.

J Clin Invest. 2017 Jan 3;127(1):280-292. doi: 10.1172/JCI88647. Epub 2016 Nov 28.

5.

The Human Functional Genomics Project: Understanding Generation of Diversity.

Pappalardo JL, Hafler DA.

Cell. 2016 Nov 3;167(4):894-896. doi: 10.1016/j.cell.2016.10.040.

PMID:
27814519
6.

NR1H3 p.Arg415Gln Is Not Associated to Multiple Sclerosis Risk.

International Multiple Sclerosis Genetics Consortium. Electronic address: cotsapas@broadinstitute.org; International Multiple Sclerosis Genetics Consortium.

Neuron. 2016 Oct 19;92(2):333-335. doi: 10.1016/j.neuron.2016.09.052.

PMID:
27764667
7.

National Heart, Lung, and Blood Institute Working Group Report on Salt in Human Health and Sickness: Building on the Current Scientific Evidence.

Oh YS, Appel LJ, Galis ZS, Hafler DA, He J, Hernandez AL, Joe B, Karumanchi SA, Maric-Bilkan C, Mattson D, Mehta NN, Randolph G, Ryan M, Sandberg K, Titze J, Tolunay E, Toney GM, Harrison DG.

Hypertension. 2016 Aug;68(2):281-8. doi: 10.1161/HYPERTENSIONAHA.116.07415. Epub 2016 Jun 20. No abstract available.

PMID:
27324228
8.

AKT isoforms modulate Th1-like Treg generation and function in human autoimmune disease.

Kitz A, de Marcken M, Gautron AS, Mitrovic M, Hafler DA, Dominguez-Villar M.

EMBO Rep. 2016 Aug;17(8):1169-83. doi: 10.15252/embr.201541905. Epub 2016 Jun 16.

PMID:
27312110
9.

Linking Genotype to Clinical Phenotype in Multiple Sclerosis: In Search of the Holy Grail.

Longbrake EE, Hafler DA.

JAMA Neurol. 2016 Jul 1;73(7):777-8. doi: 10.1001/jamaneurol.2016.1227. No abstract available.

10.

Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells.

Arterbery AS, Osafo-Addo A, Avitzur Y, Ciarleglio M, Deng Y, Lobritto SJ, Martinez M, Hafler DA, Kleinewietfeld M, Ekong UD.

J Immunol. 2016 May 15;196(10):4040-51. doi: 10.4049/jimmunol.1502276. Epub 2016 Apr 18.

11.

PD-1 marks dysfunctional regulatory T cells in malignant gliomas.

Lowther DE, Goods BA, Lucca LE, Lerner BA, Raddassi K, van Dijk D, Hernandez AL, Duan X, Gunel M, Coric V, Krishnaswamy S, Love JC, Hafler DA.

JCI Insight. 2016 Apr 21;1(5). pii: e85935.

12.

Evaluation of KIR4.1 as an Immune Target in Multiple Sclerosis.

Chastre A, Hafler DA, O'Connor KC.

N Engl J Med. 2016 Apr 14;374(15):1495-6. doi: 10.1056/NEJMc1513302. No abstract available.

13.

Multiple sclerosis: genetics, biomarkers, treatments.

Axisa PP, Hafler DA.

Curr Opin Neurol. 2016 Jun;29(3):345-53. doi: 10.1097/WCO.0000000000000319.

PMID:
27058221
14.

Power estimation for non-standardized multisite studies.

Keshavan A, Paul F, Beyer MK, Zhu AH, Papinutto N, Shinohara RT, Stern W, Amann M, Bakshi R, Bischof A, Carriero A, Comabella M, Crane JC, D'Alfonso S, Demaerel P, Dubois B, Filippi M, Fleischer V, Fontaine B, Gaetano L, Goris A, Graetz C, Gröger A, Groppa S, Hafler DA, Harbo HF, Hemmer B, Jordan K, Kappos L, Kirkish G, Llufriu S, Magon S, Martinelli-Boneschi F, McCauley JL, Montalban X, Mühlau M, Pelletier D, Pattany PM, Pericak-Vance M, Cournu-Rebeix I, Rocca MA, Rovira A, Schlaeger R, Saiz A, Sprenger T, Stecco A, Uitdehaag BM, Villoslada P, Wattjes MP, Weiner H, Wuerfel J, Zimmer C, Zipp F; International Multiple Sclerosis Genetics Consortium. Electronic address: AIVINSON@PARTNERS.ORG, Hauser SL, Oksenberg JR, Henry RG.

Neuroimage. 2016 Jul 1;134:281-94. doi: 10.1016/j.neuroimage.2016.03.051. Epub 2016 Apr 1.

15.

CNS demyelination and enhanced myelin-reactive responses after ipilimumab treatment.

Cao Y, Nylander A, Ramanan S, Goods BA, Ponath G, Zabad R, Chiang VL, Vortmeyer AO, Hafler DA, Pitt D.

Neurology. 2016 Apr 19;86(16):1553-6. doi: 10.1212/WNL.0000000000002594. Epub 2016 Mar 16. No abstract available.

PMID:
26984943
16.

The Link Between CD6 and Autoimmunity: Genetic and Cellular Associations.

Kofler DM, Farkas A, von Bergwelt-Baildon M, Hafler DA.

Curr Drug Targets. 2016;17(6):651-65. Review.

PMID:
26844569
17.

Investigating the Antigen Specificity of Multiple Sclerosis Central Nervous System-Derived Immunoglobulins.

Willis SN, Stathopoulos P, Chastre A, Compton SD, Hafler DA, O'Connor KC.

Front Immunol. 2015 Nov 25;6:600. doi: 10.3389/fimmu.2015.00600. eCollection 2015.

18.

Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells.

Hernandez AL, Kitz A, Wu C, Lowther DE, Rodriguez DM, Vudattu N, Deng S, Herold KC, Kuchroo VK, Kleinewietfeld M, Hafler DA.

J Clin Invest. 2015 Nov 2;125(11):4212-22. doi: 10.1172/JCI81151. Epub 2015 Oct 20.

19.

Class II HLA interactions modulate genetic risk for multiple sclerosis.

Moutsianas L, Jostins L, Beecham AH, Dilthey AT, Xifara DK, Ban M, Shah TS, Patsopoulos NA, Alfredsson L, Anderson CA, Attfield KE, Baranzini SE, Barrett J, Binder TMC, Booth D, Buck D, Celius EG, Cotsapas C, D'Alfonso S, Dendrou CA, Donnelly P, Dubois B, Fontaine B, Fugger L, Goris A, Gourraud PA, Graetz C, Hemmer B, Hillert J; International IBD Genetics Consortium (IIBDGC), Kockum I, Leslie S, Lill CM, Martinelli-Boneschi F, Oksenberg JR, Olsson T, Oturai A, Saarela J, Søndergaard HB, Spurkland A, Taylor B, Winkelmann J, Zipp F, Haines JL, Pericak-Vance MA, Spencer CCA, Stewart G, Hafler DA, Ivinson AJ, Harbo HF, Hauser SL, De Jager PL, Compston A, McCauley JL, Sawcer S, McVean G.

Nat Genet. 2015 Oct;47(10):1107-1113. doi: 10.1038/ng.3395. Epub 2015 Sep 7.

20.

Prospects of immune checkpoint modulators in the treatment of glioblastoma.

Preusser M, Lim M, Hafler DA, Reardon DA, Sampson JH.

Nat Rev Neurol. 2015 Sep;11(9):504-14. doi: 10.1038/nrneurol.2015.139. Epub 2015 Aug 11. Review.

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