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Items: 1 to 20 of 102


Fructose-induced inflammation and increased cortisol: A new mechanism for how sugar induces visceral adiposity.

DiNicolantonio JJ, Mehta V, Onkaramurthy N, O'Keefe JH.

Prog Cardiovasc Dis. 2018 May - Jun;61(1):3-9. doi: 10.1016/j.pcad.2017.12.001. Epub 2017 Dec 8. Review.


Immortalization of Porcine 11β-Hydroxysteroid Dehydrogenase Type 1-Transgenic Liver Cells Using SV40 Large T Antigen.

Kang HY, Choi YK, Jeong YI, Choi KC, Hyun SH, Hwang WS, Jeung EB.

Int J Mol Sci. 2017 Dec 5;18(12). pii: E2625. doi: 10.3390/ijms18122625.


The cortisol-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 in skeletal muscle in the pathogenesis of the metabolic syndrome.

Loerz C, Maser E.

J Steroid Biochem Mol Biol. 2017 Nov;174:65-71. doi: 10.1016/j.jsbmb.2017.07.030. Epub 2017 Jul 29. Review.


Macrophage 11β-HSD-1 deficiency promotes inflammatory angiogenesis.

Zhang Z, Coutinho AE, Man TY, Kipari TMJ, Hadoke PWF, Salter DM, Seckl JR, Chapman KE.

J Endocrinol. 2017 Sep;234(3):291-299. doi: 10.1530/JOE-17-0223. Epub 2017 Jul 4.


Metabolism of sex steroids is influenced by acquired adiposity-A study of young adult male monozygotic twin pairs.

Vihma V, Naukkarinen J, Turpeinen U, Hämäläinen E, Kaprio J, Rissanen A, Heinonen S, Hakkarainen A, Lundbom J, Lundbom N, Mikkola TS, Tikkanen MJ, Pietiläinen KH.

J Steroid Biochem Mol Biol. 2017 Sep;172:98-105. doi: 10.1016/j.jsbmb.2017.06.007. Epub 2017 Jun 13.


Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome.

Legeza B, Marcolongo P, Gamberucci A, Varga V, Bánhegyi G, Benedetti A, Odermatt A.

Nutrients. 2017 Apr 26;9(5). pii: E426. doi: 10.3390/nu9050426. Review.


Dietary fat and gut microbiota interactions determine diet-induced obesity in mice.

Kübeck R, Bonet-Ripoll C, Hoffmann C, Walker A, Müller VM, Schüppel VL, Lagkouvardos I, Scholz B, Engel KH, Daniel H, Schmitt-Kopplin P, Haller D, Clavel T, Klingenspor M.

Mol Metab. 2016 Oct 13;5(12):1162-1174. doi: 10.1016/j.molmet.2016.10.001. eCollection 2016 Dec.


Elevated Hypothalamic Glucocorticoid Levels Are Associated With Obesity and Hyperphagia in Male Mice.

Sefton C, Harno E, Davies A, Small H, Allen TJ, Wray JR, Lawrence CB, Coll AP, White A.

Endocrinology. 2016 Nov;157(11):4257-4265. Epub 2016 Sep 20.


Genetic Variation in the 11β-hydroxysteroid-dehydrogenase 1 Gene Determines NAFLD and Visceral Obesity.

Lutz SZ, Peter A, Machicao F, Lamprinou A, Machann J, Schick F, Königsrainer I, Königsrainer A, Fritsche A, Staiger H, Häring HU, Stefan N, Kantartzis K.

J Clin Endocrinol Metab. 2016 Dec;101(12):4743-4751. Epub 2016 Oct 7.


LSD1-a pivotal epigenetic regulator of brown and beige fat differentiation and homeostasis.

Lin JZ, Farmer SR.

Genes Dev. 2016 Aug 15;30(16):1793-5. doi: 10.1101/gad.288720.116.


Inhibition of 11β-hydroxysteroid dehydrogenase type 1 ameliorates obesity-related insulin resistance.

Shao S, Zhang X, Zhang M.

Biochem Biophys Res Commun. 2016 Sep 9;478(1):474-480. doi: 10.1016/j.bbrc.2016.06.015. Epub 2016 Jun 3.


Neuroendorine and Epigentic Mechanisms Subserving Autonomic Imbalance and HPA Dysfunction in the Metabolic Syndrome.

Lemche E, Chaban OS, Lemche AV.

Front Neurosci. 2016 Apr 14;10:142. doi: 10.3389/fnins.2016.00142. eCollection 2016. Review.


Mineralocorticoid Excess or Glucocorticoid Insufficiency: Renal and Metabolic Phenotypes in a Rat Hsd11b2 Knockout Model.

Mullins LJ, Kenyon CJ, Bailey MA, Conway BR, Diaz ME, Mullins JJ.

Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15. Erratum in: Hypertension. 2015 Sep;66(3):e20.


Association of HSD11B1 polymorphic variants and adipose tissue gene expression with metabolic syndrome, obesity and type 2 diabetes mellitus: a systematic review.

do Nascimento FV, Piccoli V, Beer MA, von Frankenberg AD, Crispim D, Gerchman F.

Diabetol Metab Syndr. 2015 Apr 28;7:38. doi: 10.1186/s13098-015-0036-1. eCollection 2015.


Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments.

Quteineh L, Vandenberghe F, Saigi Morgui N, Delacrétaz A, Choong E, Gholam-Rezaee M, Magistretti P, Bondolfi G, Von Gunten A, Preisig M, Castelao E, Vollenweider P, Waeber G, Bochud M, Kutalik Z, Conus P, Eap CB.

Pharmacogenet Genomics. 2015 May;25(5):246-58. doi: 10.1097/FPC.0000000000000131.


Effects of glucocorticoids on human brown adipocytes.

Barclay JL, Agada H, Jang C, Ward M, Wetzig N, Ho KK.

J Endocrinol. 2015 Feb;224(2):139-47. doi: 10.1530/JOE-14-0538. Epub 2014 Nov 10.


Cortisol in tissue and systemic level as a contributing factor to the development of metabolic syndrome in severely obese patients.

Constantinopoulos P, Michalaki M, Kottorou A, Habeos I, Psyrogiannis A, Kalfarentzos F, Kyriazopoulou V.

Eur J Endocrinol. 2015 Jan;172(1):69-78. doi: 10.1530/EJE-14-0626. Epub 2014 Oct 21.


Gender-dependent association of HSD11B1 single nucleotide polymorphisms with glucose and HDL-C levels.

Turek LV, Leite N, Rodrigues Souza RL, Lima JK, Milano GE, Timossi Lda S, Osiecki AC, Osiecki R, Alle LF.

Genet Mol Biol. 2014 Sep;37(3):490-5.


[New therapies for type 2 diabetes mellitus].

Puig-Domingo M, Pellitero S.

Med Clin (Barc). 2015 Jun 22;144(12):560-5. doi: 10.1016/j.medcli.2014.03.018. Epub 2014 Sep 4. Review. Spanish.


Tissue-specific dysregulation of 11β-hydroxysteroid dehydrogenase type 1 in overweight/obese women with polycystic ovary syndrome compared with weight-matched controls.

Gambineri A, Fanelli F, Tomassoni F, Munarini A, Pagotto U, Andrew R, Walker BR, Pasquali R.

Eur J Endocrinol. 2014 Jul;171(1):47-57. doi: 10.1530/EJE-13-1030. Epub 2014 Apr 17.


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