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Alterations of Cortisol Metabolism in Human Disorders.

White PC.

Horm Res Paediatr. 2018;89(5):320-330. doi: 10.1159/000485508. Epub 2018 May 29. Review.


Steroid regulation: An overlooked aspect of tolerance and chronic rejection in kidney transplantation.

Christakoudi S, Runglall M, Mobillo P, Rebollo-Mesa I, Tsui TL, Nova-Lamperti E, Norris S, Kamra Y, Hilton R, Bhandari S, Baker R, Berglund D, Carr S, Game D, Griffin S, Kalra PA, Lewis R, Mark PB, Marks SD, Macphee I, McKane W, Mohaupt MG, Pararajasingam R, Kon SP, Serón D, Sinha M, Tucker B, Viklický O, Lechler RI, Lord GM, Stahl D, Hernandez-Fuentes MP.

Mol Cell Endocrinol. 2018 Sep 15;473:205-216. doi: 10.1016/j.mce.2018.01.021. Epub 2018 Feb 7.


Association of HSD11B1 gene polymorphisms with type 2 diabetes and metabolic syndrome in South Indian population.

Devang N, Satyamoorthy K, Rai PS, Nandini M, Rao S, Phani NM, Adhikari P.

Diabetes Res Clin Pract. 2017 Sep;131:142-148. doi: 10.1016/j.diabres.2017.07.011. Epub 2017 Jul 13.


Association between ins4436A in 11β-hydroxysteroid dehydrogenase type 1 gene and essential hypertension in Polish population.

Hejduk P, Sakowicz A, Pietrucha T.

Postepy Hig Med Dosw (Online). 2015 Nov 17;69:1245-50.


Mineralocorticoid Excess or Glucocorticoid Insufficiency: Renal and Metabolic Phenotypes in a Rat Hsd11b2 Knockout Model.

Mullins LJ, Kenyon CJ, Bailey MA, Conway BR, Diaz ME, Mullins JJ.

Hypertension. 2015 Sep;66(3):667-73. doi: 10.1161/HYPERTENSIONAHA.115.05262. Epub 2015 Jun 15. Erratum in: Hypertension. 2015 Sep;66(3):e20.


11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess.

Morgan SA, McCabe EL, Gathercole LL, Hassan-Smith ZK, Larner DP, Bujalska IJ, Stewart PM, Tomlinson JW, Lavery GG.

Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):E2482-91. doi: 10.1073/pnas.1323681111. Epub 2014 Jun 2.


Variants of 11β-hydroxysteroid dehydrogenase (HSD11B) gene type 1 and 2 in Chinese obese adolescents.

Ruan LL, Xu J, Wang CL, Zou CC.

J Endocrinol Invest. 2014 Jun;37(6):565-73. doi: 10.1007/s40618-014-0075-8. Epub 2014 Apr 11.


Tissue-specific dysregulation of cortisol regeneration by 11βHSD1 in obesity: has it promised too much?

Stomby A, Andrew R, Walker BR, Olsson T.

Diabetologia. 2014 Jun;57(6):1100-10. doi: 10.1007/s00125-014-3228-6. Epub 2014 Apr 8. Review.


Variation in genes that regulate blood pressure are associated with glomerular filtration rate in Chinese.

Montasser ME, Shimmin LC, Gu D, Chen J, Gu C, Kelly TN, Jaquish CE, Rice TK, Rao DC, Cao J, Chen J, De-PeLiu, Whelton PK, Hamm LL, He J, Hixson JE.

PLoS One. 2014 Mar 21;9(3):e92468. doi: 10.1371/journal.pone.0092468. eCollection 2014.


Evidence for a role of sterol 27-hydroxylase in glucocorticoid metabolism in vivo.

Vögeli I, Jung HH, Dick B, Erickson SK, Escher R, Funder JW, Frey FJ, Escher G.

J Endocrinol. 2013 Oct 4;219(2):119-29. doi: 10.1530/JOE-13-0141. Print 2013 Nov.


Association between a 11β-hydroxysteroid dehydrogenase type 1 gene polymorphism and metabolic syndrome in a South Indian population.

Gandhi K, Adhikari P, Basu A, Achappa B.

Metab Syndr Relat Disord. 2013 Dec;11(6):397-402. doi: 10.1089/met.2013.0049. Epub 2013 Jul 20.


Modulatory effect of BclI GR gene polymorphisms on the obesity phenotype in Brazilian patients with Cushing's disease.

Moreira RP, Bachega TA, Machado MC, Mendonca BB, Bronstein MD, Villares Fragoso MC.

Clinics (Sao Paulo). 2013 May;68(5):579-85. doi: 10.6061/clinics/2013(05)01.


Glucocorticoid synthesis-related genes: HSD11B1 and HSD11B2 in hypertensive disorders in pregnancy.

Shimodaira M, Nakayama T, Sato I, Sato N, Izawa N, Mizutani Y, Furuya K, Yamamoto T.

Gynecol Endocrinol. 2013 Jul;29(7):657-61. doi: 10.3109/09513590.2013.788623. Epub 2013 May 9.


11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects.

Gathercole LL, Lavery GG, Morgan SA, Cooper MS, Sinclair AJ, Tomlinson JW, Stewart PM.

Endocr Rev. 2013 Aug;34(4):525-55. doi: 10.1210/er.2012-1050. Epub 2013 Apr 23. Review.


11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.

Pereira CD, Azevedo I, Monteiro R, Martins MJ.

Diabetes Obes Metab. 2012 Oct;14(10):869-81. doi: 10.1111/j.1463-1326.2012.01582.x. Epub 2012 Mar 8. Review.


Altered placental development in undernourished rats: role of maternal glucocorticoids.

Belkacemi L, Jelks A, Chen CH, Ross MG, Desai M.

Reprod Biol Endocrinol. 2011 Aug 1;9:105. doi: 10.1186/1477-7827-9-105.


Effects of menopause on hepatic 11β-hydroxysteroid dehydrogenase type 1 activity and adrenal sensitivity to adrenocorticotropin in healthy non-obese women.

Li S, Liu W, Wang L, Huang R, Chen Q, Wu Y, Cai Y.

Gynecol Endocrinol. 2011 Oct;27(10):794-9. doi: 10.3109/09513590.2010.507288. Epub 2011 Jul 8.


A combination of polymorphisms in HSD11B1 associates with in vivo 11{beta}-HSD1 activity and metabolic syndrome in women with and without polycystic ovary syndrome.

Gambineri A, Tomassoni F, Munarini A, Stimson RH, Mioni R, Pagotto U, Chapman KE, Andrew R, Mantovani V, Pasquali R, Walker BR.

Eur J Endocrinol. 2011 Aug;165(2):283-92. doi: 10.1530/EJE-11-0091. Epub 2011 May 27.


Common variation at the 11-β hydroxysteroid dehydrogenase type 1 gene is associated with left ventricular mass.

Rahman TJ, Mayosi BM, Hall D, Avery PJ, Stewart PM, Connell JM, Watkins H, Keavney B.

Circ Cardiovasc Genet. 2011 Apr;4(2):156-62. doi: 10.1161/CIRCGENETICS.110.958496. Epub 2011 Mar 14.


Functional effects of polymorphisms in the human gene encoding 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1): a sequence variant at the translation start of 11 beta-HSD1 alters enzyme levels.

Malavasi EL, Kelly V, Nath N, Gambineri A, Dakin RS, Pagotto U, Pasquali R, Walker BR, Chapman KE.

Endocrinology. 2010 Jan;151(1):195-202. doi: 10.1210/en.2009-0663. Epub 2009 Nov 24.

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