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Items: 1 to 20 of 117

1.

Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia.

Edin ML, Gholipour Hamedani B, Gruzdev A, Graves JP, Lih FB, Arbes SJ, Singh R, Orjuela Leon AC, Bradbury JA, DeGraff LM, Hoopes SL, Arand M, Zeldin D.

J Biol Chem. 2018 Jan 3. pii: jbc.RA117.000298. doi: 10.1074/jbc.RA117.000298. [Epub ahead of print]

2.

Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia.

Bettaieb A, Koike S, Hsu MF, Ito Y, Chahed S, Bachaalany S, Gruzdev A, Calvo-Rubio M, Lee KSS, Inceoglu B, Imig JD, Villalba JM, Zeldin DC, Hammock BD, Haj FG.

Biochim Biophys Acta. 2017 Nov;1861(11 Pt A):2758-2765. doi: 10.1016/j.bbagen.2017.07.021. Epub 2017 Jul 27.

PMID:
28757338
3.

Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury.

Bettaieb A, Koike S, Chahed S, Zhao Y, Bachaalany S, Hashoush N, Graham J, Fatima H, Havel PJ, Gruzdev A, Zeldin DC, Hammock BD, Haj FG.

FEBS J. 2017 Jul;284(13):1970-1986. doi: 10.1111/febs.14100. Epub 2017 May 29.

PMID:
28485854
4.

Characterization of the Tissue Distribution of the Mouse Cyp2c Subfamily by Quantitative PCR Analysis.

Graves JP, Gruzdev A, Bradbury JA, DeGraff LM, Edin ML, Zeldin DC.

Drug Metab Dispos. 2017 Jul;45(7):807-816. doi: 10.1124/dmd.117.075697. Epub 2017 Apr 27.

5.

Hematological profile of untreated or ionizing radiation-exposed cyclooxygenase-2-deficient mice.

Hofer M, Hoferová Z, Dušek L, Souček K, Gruzdev A.

Physiol Res. 2017 Sep 22;66(4):673-676. Epub 2017 Apr 12.

6.

Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice.

Hoopes SL, Gruzdev A, Edin ML, Graves JP, Bradbury JA, Flake GP, Lih FB, DeGraff LM, Zeldin DC.

PLoS One. 2017 Apr 6;12(4):e0175348. doi: 10.1371/journal.pone.0175348. eCollection 2017.

7.

20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension.

Garcia V, Gilani A, Shkolnik B, Pandey V, Zhang FF, Dakarapu R, Gandham SK, Reddy NR, Graves JP, Gruzdev A, Zeldin DC, Capdevila JH, Falck JR, Schwartzman ML.

Circ Res. 2017 May 26;120(11):1776-1788. doi: 10.1161/CIRCRESAHA.116.310525. Epub 2017 Mar 21.

PMID:
28325781
8.

Plasma 15-Hydroxyeicosatetraenoic Acid Predicts Treatment Outcomes in Aspirin-Exacerbated Respiratory Disease.

Jerschow E, Edin ML, Pelletier T, Abuzeid WM, Akbar NA, Gibber M, Fried M, Lih FB, Gruzdev A, Bradbury JA, Han W, Hudes G, Keskin T, Schuster VL, Spivack S, Zeldin DC, Rosenstreich D.

J Allergy Clin Immunol Pract. 2017 Jul - Aug;5(4):998-1007.e2. doi: 10.1016/j.jaip.2016.11.021. Epub 2017 Jan 31.

PMID:
28159558
9.

Cangrelor With and Without Glycoprotein IIb/IIIa Inhibitors in Patients Undergoing Percutaneous Coronary Intervention.

Vaduganathan M, Harrington RA, Stone GW, Deliargyris EN, Steg PG, Gibson CM, Hamm CW, Price MJ, Menozzi A, Prats J, Elkin S, Mahaffey KW, White HD, Bhatt DL; CHAMPION Investigators.

J Am Coll Cardiol. 2017 Jan 17;69(2):176-185. doi: 10.1016/j.jacc.2016.10.055.

PMID:
28081827
10.

Contribution of alveolar type II cell-derived cyclooxygenase-2 to basal airway function, lung inflammation, and lung fibrosis.

Cheng J, Dackor RT, Bradbury JA, Li H, DeGraff LM, Hong LK, King D, Lih FB, Gruzdev A, Edin ML, Travlos GS, Flake GP, Tomer KB, Zeldin DC.

FASEB J. 2016 Jan;30(1):160-73. doi: 10.1096/fj.14-268458. Epub 2015 Sep 22.

11.

Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation.

Graves JP, Gruzdev A, Bradbury JA, DeGraff LM, Li H, House JS, Hoopes SL, Edin ML, Zeldin DC.

Drug Metab Dispos. 2015 Aug;43(8):1169-80. doi: 10.1124/dmd.115.064139. Epub 2015 May 20.

12.

Epoxyeicosatrienoic acids regulate macrophage polarization and prevent LPS-induced cardiac dysfunction.

Dai M, Wu L, He Z, Zhang S, Chen C, Xu X, Wang P, Gruzdev A, Zeldin DC, Wang DW.

J Cell Physiol. 2015 Sep;230(9):2108-19. doi: 10.1002/jcp.24939.

13.

[Extinction of large herbivore mammals: niche characteristics of musk ox Ovibos moschatus and reindeer Rangifer tarandus coexisting in isolation].

Sheremet'ev IS, Rosenfel'd SB, Sipko TP, Gruzdev AR.

Zh Obshch Biol. 2014 Jan-Feb;75(1):62-73. Russian.

PMID:
25486798
14.

CYP2J2 attenuates metabolic dysfunction in diabetic mice by reducing hepatic inflammation via the PPARγ.

Li R, Xu X, Chen C, Wang Y, Gruzdev A, Zeldin DC, Wang DW.

Am J Physiol Endocrinol Metab. 2015 Feb 15;308(4):E270-82. doi: 10.1152/ajpendo.00118.2014. Epub 2014 Nov 11.

15.

The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease.

Schuck RN, Zha W, Edin ML, Gruzdev A, Vendrov KC, Miller TM, Xu Z, Lih FB, DeGraff LM, Tomer KB, Jones HM, Makowski L, Huang L, Poloyac SM, Zeldin DC, Lee CR.

PLoS One. 2014 Oct 13;9(10):e110162. doi: 10.1371/journal.pone.0110162. eCollection 2014.

16.

[The prevalence of different Streptococcus pneumoniaе serotypes in the children presenting with ENT infections or carrying nasopharyngeal pathogens].

Boronina LG, Samatova EV, Druĭ AE, Panina EIu, Kochneva NA, Vodovoz NIu, Murunova NV, Gruzdev AI, Lakhno TI.

Vestn Otorinolaringol. 2013;(5):54-8. Russian.

PMID:
24300763
17.

Cyclooxygenase-2 inhibits T helper cell type 9 differentiation during allergic lung inflammation via down-regulation of IL-17RB.

Li H, Edin ML, Bradbury JA, Graves JP, DeGraff LM, Gruzdev A, Cheng J, Dackor RT, Wang PM, Bortner CD, Garantziotis S, Jetten AM, Zeldin DC.

Am J Respir Crit Care Med. 2013 Apr 15;187(8):812-22. doi: 10.1164/rccm.201211-2073OC.

18.

Characterization of four new mouse cytochrome P450 enzymes of the CYP2J subfamily.

Graves JP, Edin ML, Bradbury JA, Gruzdev A, Cheng J, Lih FB, Masinde TA, Qu W, Clayton NP, Morrison JP, Tomer KB, Zeldin DC.

Drug Metab Dispos. 2013 Apr;41(4):763-73. doi: 10.1124/dmd.112.049429. Epub 2013 Jan 11.

19.

Regulation of T helper cell subsets by cyclooxygenases and their metabolites.

Li H, Edin ML, Gruzdev A, Cheng J, Bradbury JA, Graves JP, DeGraff LM, Zeldin DC.

Prostaglandins Other Lipid Mediat. 2013 Jul-Aug;104-105:74-83. doi: 10.1016/j.prostaglandins.2012.11.002. Epub 2012 Nov 28. Review.

20.

Altered behavioral phenotypes in soluble epoxide hydrolase knockout mice: effects of traumatic brain injury.

Strauss KI, Gruzdev A, Zeldin DC.

Prostaglandins Other Lipid Mediat. 2013 Jul-Aug;104-105:18-24. doi: 10.1016/j.prostaglandins.2012.07.005. Epub 2012 Aug 16.

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