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Items: 1 to 20 of 214


Fighting against a protean enemy: immunosenescence, vaccines, and healthy aging.

Del Giudice G, Goronzy JJ, Grubeck-Loebenstein B, Lambert PH, Mrkvan T, Stoddard JJ, Doherty TM.

NPJ Aging Mech Dis. 2017 Dec 21;4:1. doi: 10.1038/s41514-017-0020-0. eCollection 2018.


Zinc-induced Metallothionein in centenarian offspring from a large European population: the MARK-AGE Project.

Giacconi R, Costarelli L, Piacenza F, Basso A, Bürkle A, Moreno-Villanueva M, Grune T, Weber D, Stuetz W, Gonos ES, Schön C, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Franceschi C, Hervonen A, Slagboom E, Ciccarone F, Zampieri M, Caiafa P, Jansen E, Dollé MET, Breusing N, Mocchegiani E, Malavolta M.

J Gerontol A Biol Sci Med Sci. 2017 Oct 17. doi: 10.1093/gerona/glx192. [Epub ahead of print]


Protection against Tetanus and Diphtheria in Europe: The impact of age, gender and country of origin based on data from the MARK-AGE Study.

Weinberger B, Keller M, Putzer C, Breitenberger D, Koller B, Fiegl S, Moreno-Villanueva M, Bernhardt J, Franceschi C, Voutetakis K, Gonos ES, Hurme M, Sikora E, Toussaint O, Debacq-Chainiaux F, Grune T, Breusing N, Bürkle A, Grubeck-Loebenstein B.

Exp Gerontol. 2017 Oct 7. pii: S0531-5565(17)30516-8. doi: 10.1016/j.exger.2017.08.037. [Epub ahead of print]


Increased IL-15 Production and Accumulation of Highly Differentiated CD8+ Effector/Memory T Cells in the Bone Marrow of Persons with Cytomegalovirus.

Pangrazzi L, Naismith E, Meryk A, Keller M, Jenewein B, Trieb K, Grubeck-Loebenstein B.

Front Immunol. 2017 Jun 19;8:715. doi: 10.3389/fimmu.2017.00715. eCollection 2017.


Long-term maintenance of diphtheria-specific antibodies after booster vaccination is hampered by latent infection with Cytomegalovirus.

Weinberger B, Keller M, Grubeck-Loebenstein B.

Immun Ageing. 2017 Jun 26;14:16. doi: 10.1186/s12979-017-0099-y. eCollection 2017.


"Inflamm-aging" influences immune cell survival factors in human bone marrow.

Pangrazzi L, Meryk A, Naismith E, Koziel R, Lair J, Krismer M, Trieb K, Grubeck-Loebenstein B.

Eur J Immunol. 2017 Mar;47(3):481-492. doi: 10.1002/eji.201646570. Epub 2017 Jan 11.


Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35-74 Years) General Population: A Cross-Sectional Study in Six European Countries.

Stuetz W, Weber D, Dollé ME, Jansen E, Grubeck-Loebenstein B, Fiegl S, Toussaint O, Bernhardt J, Gonos ES, Franceschi C, Sikora E, Moreno-Villanueva M, Breusing N, Grune T, Bürkle A.

Nutrients. 2016 Sep 30;8(10). pii: E614.


Booster vaccination against tetanus and diphtheria: insufficient protection against diphtheria in young and elderly adults.

Grasse M, Meryk A, Schirmer M, Grubeck-Loebenstein B, Weinberger B.

Immun Ageing. 2016 Sep 5;13(1):26. doi: 10.1186/s12979-016-0081-0. eCollection 2016.


Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study.

Ciccarone F, Malavolta M, Calabrese R, Guastafierro T, Bacalini MG, Reale A, Franceschi C, Capri M, Hervonen A, Hurme M, Grubeck-Loebenstein B, Koller B, Bernhardt J, Schӧn C, Slagboom PE, Toussaint O, Sikora E, Gonos ES, Breusing N, Grune T, Jansen E, Dollé M, Moreno-Villanueva M, Sindlinger T, Bürkle A, Zampieri M, Caiafa P.

Aging Cell. 2016 Aug;15(4):755-65. doi: 10.1111/acel.12485. Epub 2016 May 11.


CD58/CD2 Is the Primary Costimulatory Pathway in Human CD28-CD8+ T Cells.

Leitner J, Herndler-Brandstetter D, Zlabinger GJ, Grubeck-Loebenstein B, Steinberger P.

J Immunol. 2015 Jul 15;195(2):477-87. doi: 10.4049/jimmunol.1401917. Epub 2015 Jun 3.


[Immunogerontology - Research into aging].

Grubeck-Loebenstein B.

Z Rheumatol. 2015 Jun;74(5):435-7. doi: 10.1007/s00393-014-1562-1. German. No abstract available.


The stimulatory effect of the TLR4-mediated adjuvant glucopyranosyl lipid A is well preserved in old age.

Weinberger B, Joos C, Reed SG, Coler R, Grubeck-Loebenstein B.

Biogerontology. 2016 Feb;17(1):177-87. doi: 10.1007/s10522-015-9576-x. Epub 2015 May 9.


MARK-AGE population: From the human model to new insights.

Capri M, Moreno-Villanueva M, Cevenini E, Pini E, Scurti M, Borelli V, Palmas MG, Zoli M, Schön C, Siepelmeyer A, Bernhardt J, Fiegl S, Zondag G, de Craen AJ, Hervonen A, Hurme M, Sikora E, Gonos ES, Voutetakis K, Toussaint O, Debacq-Chainiaux F, Grubeck-Loebenstein B, Bürkle A, Franceschi C.

Mech Ageing Dev. 2015 Nov;151:13-7. doi: 10.1016/j.mad.2015.03.010. Epub 2015 Apr 2. Review. No abstract available.


MARK-AGE biomarkers of ageing.

Bürkle A, Moreno-Villanueva M, Bernhard J, Blasco M, Zondag G, Hoeijmakers JH, Toussaint O, Grubeck-Loebenstein B, Mocchegiani E, Collino S, Gonos ES, Sikora E, Gradinaru D, Dollé M, Salmon M, Kristensen P, Griffiths HR, Libert C, Grune T, Breusing N, Simm A, Franceschi C, Capri M, Talbot D, Caiafa P, Friguet B, Slagboom PE, Hervonen A, Hurme M, Aspinall R.

Mech Ageing Dev. 2015 Nov;151:2-12. doi: 10.1016/j.mad.2015.03.006. Epub 2015 Mar 24. Review.


How sex and age affect immune responses, susceptibility to infections, and response to vaccination.

Giefing-Kröll C, Berger P, Lepperdinger G, Grubeck-Loebenstein B.

Aging Cell. 2015 Jun;14(3):309-21. doi: 10.1111/acel.12326. Epub 2015 Feb 26. Review.


[Principles of biological aging].

Schosserer M, Grubeck-Loebenstein B, Grillari J.

Z Gerontol Geriatr. 2015 Apr;48(3):285-94. doi: 10.1007/s00391-015-0857-4. Epub 2015 Feb 21. German.


Plasma cell numbers decrease in bone marrow of old patients.

Pritz T, Lair J, Ban M, Keller M, Weinberger B, Krismer M, Grubeck-Loebenstein B.

Eur J Immunol. 2015 Mar;45(3):738-46. doi: 10.1002/eji.201444878. Epub 2014 Dec 23.


Vaccines for the elderly.

Del Giudice G, Weinberger B, Grubeck-Loebenstein B.

Gerontology. 2015;61(3):203-10. doi: 10.1159/000366162. Epub 2014 Nov 13. Review.


The aging bone marrow and its impact on immune responses in old age.

Pritz T, Weinberger B, Grubeck-Loebenstein B.

Immunol Lett. 2014 Nov;162(1 Pt B):310-5. doi: 10.1016/j.imlet.2014.06.016. Epub 2014 Jul 8. Review.


Characterization of the inflammatory infiltrate in Streptococcus pneumoniae pneumonia in young and elderly patients.

Menter T, Giefing-Kroell C, Grubeck-Loebenstein B, Tzankov A.

Pathobiology. 2014;81(3):160-7. doi: 10.1159/000360165. Epub 2014 Apr 15.

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