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Items: 1 to 20 of 46

1.

Munc18-2 is required for Syntaxin 11 Localization on the Plasma Membrane in Cytotoxic T-Lymphocytes.

Dieckmann NM, Hackmann Y, Aricò M, Griffiths GM.

Traffic. 2015 Dec;16(12):1330-41. doi: 10.1111/tra.12337.

2.

Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis.

Stinchcombe JC, Randzavola LO, Angus KL, Mantell JM, Verkade P, Griffiths GM.

Curr Biol. 2015 Dec 21;25(24):3239-44. doi: 10.1016/j.cub.2015.10.028.

3.

Genetic predisposition to hemophagocytic lymphohistiocytosis: Report on 500 patients from the Italian registry.

Cetica V, Sieni E, Pende D, Danesino C, De Fusco C, Locatelli F, Micalizzi C, Putti MC, Biondi A, Fagioli F, Moretta L, Griffiths GM, Luzzatto L, Aricò M.

J Allergy Clin Immunol. 2016 Jan;137(1):188-96.e4. doi: 10.1016/j.jaci.2015.06.048.

4.

Actin depletion initiates events leading to granule secretion at the immunological synapse.

Ritter AT, Asano Y, Stinchcombe JC, Dieckmann NM, Chen BC, Gawden-Bone C, van Engelenburg S, Legant W, Gao L, Davidson MW, Betzig E, Lippincott-Schwartz J, Griffiths GM.

Immunity. 2015 May 19;42(5):864-76. doi: 10.1016/j.immuni.2015.04.013.

5.

Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding.

Cetica V, Hackmann Y, Grieve S, Sieni E, Ciambotti B, Coniglio ML, Pende D, Gilmour K, Romagnoli P, Griffiths GM, Aricò M.

J Allergy Clin Immunol. 2015 May;135(5):1310-8.e1. doi: 10.1016/j.jaci.2014.08.039.

6.

The biogenesis of lysosomes and lysosome-related organelles.

Luzio JP, Hackmann Y, Dieckmann NM, Griffiths GM.

Cold Spring Harb Perspect Biol. 2014 Sep 2;6(9):a016840. doi: 10.1101/cshperspect.a016840. Review.

7.

Communication, the centrosome and the immunological synapse.

Stinchcombe JC, Griffiths GM.

Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650). pii: 20130463. doi: 10.1098/rstb.2013.0463. Review.

8.

Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL.

Jenkins MR, Stinchcombe JC, Au-Yeung BB, Asano Y, Ritter AT, Weiss A, Griffiths GM.

Elife. 2014 Mar 4;3:e01310. doi: 10.7554/eLife.01310.

9.

Hedgehog signaling controls T cell killing at the immunological synapse.

de la Roche M, Ritter AT, Angus KL, Dinsmore C, Earnshaw CH, Reiter JF, Griffiths GM.

Science. 2013 Dec 6;342(6163):1247-50. doi: 10.1126/science.1244689.

10.

Syntaxin binding mechanism and disease-causing mutations in Munc18-2.

Hackmann Y, Graham SC, Ehl S, Höning S, Lehmberg K, Aricò M, Owen DJ, Griffiths GM.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4482-91. doi: 10.1073/pnas.1313474110.

11.

The role of the cytoskeleton at the immunological synapse.

Ritter AT, Angus KL, Griffiths GM.

Immunol Rev. 2013 Nov;256(1):107-17. doi: 10.1111/imr.12117. Review.

12.

Open questions: missing pieces from the immunological jigsaw puzzle.

Griffiths GM.

BMC Biol. 2013 Jan 31;11:10. doi: 10.1186/1741-7007-11-10. No abstract available.

13.

Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency.

Lang PA, Shaabani N, Borkens S, Honke N, Scheu S, Booth S, Brenner D, Meryk A, Barthuber C, Recher M, Mak TW, Ohashi PS, Häussinger D, Griffiths GM, Thrasher AJ, Bouma G, Lang KS.

J Allergy Clin Immunol. 2013 Mar;131(3):815-24. doi: 10.1016/j.jaci.2012.08.050.

14.

Cell polarisation and the immunological synapse.

Angus KL, Griffiths GM.

Curr Opin Cell Biol. 2013 Feb;25(1):85-91. doi: 10.1016/j.ceb.2012.08.013. Review.

15.

Cytotoxic T lymphocyte effector function is independent of nucleus-centrosome dissociation.

Lui-Roberts WW, Stinchcombe JC, Ritter AT, Akhmanova A, Karakesisoglou I, Griffiths GM.

Eur J Immunol. 2012 Aug;42(8):2132-41. doi: 10.1002/eji.201242525.

16.

Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis.

Zhao F, Cannons JL, Dutta M, Griffiths GM, Schwartzberg PL.

Immunity. 2012 Jun 29;36(6):1003-16. doi: 10.1016/j.immuni.2012.05.017.

17.

Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems.

Stinchcombe JC, Salio M, Cerundolo V, Pende D, Arico M, Griffiths GM.

BMC Biol. 2011 Jun 28;9:45. doi: 10.1186/1741-7007-9-45.

18.

A role for Rab7 in the movement of secretory granules in cytotoxic T lymphocytes.

Daniele T, Hackmann Y, Ritter AT, Wenham M, Booth S, Bossi G, Schintler M, Auer-Grumbach M, Griffiths GM.

Traffic. 2011 Jul;12(7):902-11. doi: 10.1111/j.1600-0854.2011.01194.x.

19.

Centrosome docking at the immunological synapse is controlled by Lck signaling.

Tsun A, Qureshi I, Stinchcombe JC, Jenkins MR, de la Roche M, Kleczkowska J, Zamoyska R, Griffiths GM.

J Cell Biol. 2011 Feb 21;192(4):663-74. doi: 10.1083/jcb.201008140.

20.

Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis type 3.

Sieni E, Cetica V, Santoro A, Beutel K, Mastrodicasa E, Meeths M, Ciambotti B, Brugnolo F, zur Stadt U, Pende D, Moretta L, Griffiths GM, Henter JI, Janka G, Aricò M.

J Med Genet. 2011 May;48(5):343-52. doi: 10.1136/jmg.2010.085456.

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