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Items: 1 to 20 of 21


Early postnatal soluble FGFR3 therapy prevents the atypical development of obesity in achondroplasia.

Saint-Laurent C, Garcia S, Sarrazy V, Dumas K, Authier F, Sore S, Tran A, Gual P, Gennero I, Salles JP, Gouze E.

PLoS One. 2018 Apr 13;13(4):e0195876. doi: 10.1371/journal.pone.0195876. eCollection 2018.


Current Care and Investigational Therapies in Achondroplasia.

Unger S, Bonafé L, Gouze E.

Curr Osteoporos Rep. 2017 Apr;15(2):53-60. doi: 10.1007/s11914-017-0347-2. Review.


Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice.

Garcia S, Dirat B, Tognacci T, Rochet N, Mouska X, Bonnafous S, Patouraux S, Tran A, Gual P, Le Marchand-Brustel Y, Gennero I, Gouze E.

Sci Transl Med. 2013 Sep 18;5(203):203ra124. doi: 10.1126/scitranslmed.3006247.


Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist.

Allen KD, Adams SB Jr, Mata BA, Shamji MF, Gouze E, Jing L, Nettles DL, Latt LD, Setton LA.

J Orthop Res. 2011 May;29(5):694-703. doi: 10.1002/jor.21309. Epub 2010 Dec 17.


Gene delivery of TGF-β1 induces arthrofibrosis and chondrometaplasia of synovium in vivo.

Watson RS, Gouze E, Levings PP, Bush ML, Kay JD, Jorgensen MS, Dacanay EA, Reith JW, Wright TW, Ghivizzani SC.

Lab Invest. 2010 Nov;90(11):1615-27. doi: 10.1038/labinvest.2010.145. Epub 2010 Aug 9.


Intra-articular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virus.

Kay JD, Gouze E, Oligino TJ, Gouze JN, Watson RS, Levings PP, Bush ML, Dacanay A, Nickerson DM, Robbins PD, Evans CH, Ghivizzani SC.

J Gene Med. 2009 Jul;11(7):605-14. doi: 10.1002/jgm.1334.


Perspectives on the use of gene therapy for chronic joint diseases.

Ghivizzani SC, Gouze E, Gouze JN, Kay JD, Bush ML, Watson RS, Levings PP, Nickerson DM, Colahan PT, Robbins PD, Evans CH.

Curr Gene Ther. 2008 Aug;8(4):273-86. Review.


Facilitated endogenous repair: making tissue engineering simple, practical, and economical.

Evans CH, Palmer GD, Pascher A, Porter R, Kwong FN, Gouze E, Gouze JN, Liu F, Steinert A, Betz O, Betz V, Vrahas M, Ghivizzani SC.

Tissue Eng. 2007 Aug;13(8):1987-93. Review.


Transgene persistence and cell turnover in the diarthrodial joint: implications for gene therapy of chronic joint diseases.

Gouze E, Gouze JN, Palmer GD, Pilapil C, Evans CH, Ghivizzani SC.

Mol Ther. 2007 Jun;15(6):1114-20. Epub 2007 Apr 17.


[Gene therapy for osteoarticular disorders].

Gouze JN, Evans CH, Ghivizzani SC, Gouze E.

Med Sci (Paris). 2007 Mar;23(3):303-9. Review. French.


Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1beta.

Gouze JN, Gouze E, Popp MP, Bush ML, Dacanay EA, Kay JD, Levings PP, Patel KR, Saran JP, Watson RS, Ghivizzani SC.

Arthritis Res Ther. 2006;8(6):R173.


The 3rd International Meeting on Gene Therapy in Rheumatology and Orthopaedics.

Evans CH, Ghivizzani SC, Gouze E, Rediske JJ, Schwarz EM, Robbins PD.

Arthritis Res Ther. 2005;7(6):273-8. Epub 2005 Oct 28.


Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro.

Palmer GD, Steinert A, Pascher A, Gouze E, Gouze JN, Betz O, Johnstone B, Evans CH, Ghivizzani SC.

Mol Ther. 2005 Aug;12(2):219-28.


Enhanced repair of the anterior cruciate ligament by in situ gene transfer: evaluation in an in vitro model.

Pascher A, Steinert AF, Palmer GD, Betz O, Gouze JN, Gouze E, Pilapil C, Ghivizzani SC, Evans CH, Murray MM.

Mol Ther. 2004 Aug;10(2):327-36.


In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors.

Gouze JN, Stoddart MJ, Gouze E, Palmer GD, Ghivizzani SC, Grodzinsky AJ, Evans CH.

Methods Mol Med. 2004;100:147-64.


A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer.

Gouze JN, Gouze E, Palmer GD, Liew VS, Pascher A, Betz OB, Thornhill TS, Evans CH, Grodzinsky AJ, Ghivizzani SC.

Arthritis Res Ther. 2003;5(5):R301-9. Epub 2003 Aug 1.


Lentiviral-mediated gene delivery to synovium: potent intra-articular expression with amplification by inflammation.

Gouze E, Pawliuk R, Gouze JN, Pilapil C, Fleet C, Palmer GD, Evans CH, Leboulch P, Ghivizzani SC.

Mol Ther. 2003 Apr;7(4):460-6.


Development of gene-based therapies for cartilage repair.

Palmer G, Pascher A, Gouze E, Gouze JN, Betz O, Spector M, Robbins PD, Evans CH, Ghivizzani SC.

Crit Rev Eukaryot Gene Expr. 2002;12(4):259-73. Review.


Gene transfer to articular chondrocytes with recombinant adenovirus.

Palmer GD, Gouze E, Gouze JN, Betz OB, Evans CH, Ghivizzani SC.

Methods Mol Biol. 2003;215:235-46. No abstract available.


In vivo gene delivery to synovium by lentiviral vectors.

Gouze E, Pawliuk R, Pilapil C, Gouze JN, Fleet C, Palmer GD, Evans CH, Leboulch P, Ghivizzani SC.

Mol Ther. 2002 Apr;5(4):397-404.

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