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Items: 1 to 20 of 77

1.

Intracellular Signaling Pathways Involved in (S)- and (R)-Ketamine Antidepressant Actions.

Zanos P, Gould TD.

Biol Psychiatry. 2018 Jan 1;83(1):2-4. doi: 10.1016/j.biopsych.2017.10.026. No abstract available.

2.
3.

Correction to "Synthesis and N-Methyl-d-aspartate (NMDA) Receptor Activity of Ketamine Metabolites".

Morris PJ, Moaddel R, Zanos P, Moore CE, Gould TD, Zarate CA Jr, Thomas CJ.

Org Lett. 2017 Oct 6;19(19):5494. doi: 10.1021/acs.orglett.7b02839. Epub 2017 Sep 21. No abstract available.

PMID:
28933164
4.

Dopamine and Stress System Modulation of Sex Differences in Decision Making.

Georgiou P, Zanos P, Bhat S, Tracy JK, Merchenthaler IJ, McCarthy MM, Gould TD.

Neuropsychopharmacology. 2018 Jan;43(2):313-324. doi: 10.1038/npp.2017.161. Epub 2017 Jul 25.

PMID:
28741626
5.

Zanos et al. reply.

Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KSS, Fang Y, Huang XP, Mayo CL, Albuquerque EX, Thompson SM, Thomas CJ, Zarate CA, Gould TD.

Nature. 2017 Jun 21;546(7659):E4-E5. doi: 10.1038/nature22085. No abstract available.

6.

Animal models to improve our understanding and treatment of suicidal behavior.

Gould TD, Georgiou P, Brenner LA, Brundin L, Can A, Courtet P, Donaldson ZR, Dwivedi Y, Guillaume S, Gottesman II, Kanekar S, Lowry CA, Renshaw PF, Rujescu D, Smith EG, Turecki G, Zanos P, Zarate CA Jr, Zunszain PA, Postolache TT.

Transl Psychiatry. 2017 Apr 11;7(4):e1092. doi: 10.1038/tp.2017.50. Review.

7.

A Negative Allosteric Modulator for α5 Subunit-Containing GABA Receptors Exerts a Rapid and Persistent Antidepressant-Like Action without the Side Effects of the NMDA Receptor Antagonist Ketamine in Mice.

Zanos P, Nelson ME, Highland JN, Krimmel SR, Georgiou P, Gould TD, Thompson SM.

eNeuro. 2017 Mar 7;4(1). pii: ENEURO.0285-16.2017. doi: 10.1523/ENEURO.0285-16.2017. eCollection 2017 Jan-Feb.

8.

Reduced levels of Cacna1c attenuate mesolimbic dopamine system function.

Terrillion CE, Dao DT, Cachope R, Lobo MK, Puche AC, Cheer JF, Gould TD.

Genes Brain Behav. 2017 Jun;16(5):495-505. doi: 10.1111/gbb.12371. Epub 2017 Mar 13.

PMID:
28186690
9.

Decreased Nucleus Accumbens Expression of Psychiatric Disorder Risk Gene Cacna1c Promotes Susceptibility to Social Stress.

Terrillion CE, Francis TC, Puche AC, Lobo MK, Gould TD.

Int J Neuropsychopharmacol. 2017 May 1;20(5):428-433. doi: 10.1093/ijnp/pyw112.

10.

Ketamine Mechanism of Action: Separating the Wheat from the Chaff.

Gould TD, Zanos P, Zarate CA Jr.

Neuropsychopharmacology. 2017 Jan;42(1):368-369. doi: 10.1038/npp.2016.210. No abstract available.

11.

Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations.

Le NT, Chang L, Kovlyagina I, Georgiou P, Safren N, Braunstein KE, Kvarta MD, Van Dyke AM, LeGates TA, Philips T, Morrison BM, Thompson SM, Puche AC, Gould TD, Rothstein JD, Wong PC, Monteiro MJ.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7580-E7589. Epub 2016 Nov 9.

12.

Reply to: Antidepressant Actions of Ketamine Versus Hydroxynorketamine.

Zanos P, Moaddel R, Morris PJ, Wainer IW, Albuquerque EX, Thompson SM, Thomas CJ, Zarate CA Jr, Gould TD.

Biol Psychiatry. 2017 Apr 15;81(8):e69-e71. doi: 10.1016/j.biopsych.2016.08.039. Epub 2016 Sep 30. No abstract available.

13.

Chronic lithium treatment rectifies maladaptive dopamine release in the nucleus accumbens.

Can A, Frost DO, Cachope R, Cheer JF, Gould TD.

J Neurochem. 2016 Nov;139(4):576-585. doi: 10.1111/jnc.13769. Epub 2016 Oct 18.

14.

Irving I. Gottesman (1930-2016): the multifactorial threshold model of complex phenotypes mediated by endophenotype strategies.

Gould TD.

Genes Brain Behav. 2016 Nov;15(8):775-776. doi: 10.1111/gbb.12345. No abstract available.

PMID:
27681168
15.

Effects of Ketamine and Ketamine Metabolites on Evoked Striatal Dopamine Release, Dopamine Receptors, and Monoamine Transporters.

Can A, Zanos P, Moaddel R, Kang HJ, Dossou KS, Wainer IW, Cheer JF, Frost DO, Huang XP, Gould TD.

J Pharmacol Exp Ther. 2016 Oct;359(1):159-70. doi: 10.1124/jpet.116.235838. Epub 2016 Jul 28.

16.

NMDAR inhibition-independent antidepressant actions of ketamine metabolites.

Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, Albuquerque EX, Thompson SM, Thomas CJ, Zarate CA Jr, Gould TD.

Nature. 2016 May 26;533(7604):481-6. doi: 10.1038/nature17998. Epub 2016 May 4.

17.

Going longitudinal in biological psychiatric research: All things considered.

Gould TD, Hashimoto R, Schulze TG.

Neurosci Res. 2016 Jan;102:1-3. doi: 10.1016/j.neures.2015.12.012. Epub 2015 Dec 29. No abstract available.

PMID:
26742506
18.

Effects of environmental stress following myocardial infarction on behavioral measures and heart failure progression: The influence of isolated and group housing conditions.

Kop WJ, Galvao TF, Synowski SJ, Xu W, Can A, O'Shea KM, Gould TD, Stanley WC.

Physiol Behav. 2015 Dec 1;152(Pt A):168-74. doi: 10.1016/j.physbeh.2015.09.024. Epub 2015 Sep 28.

PMID:
26423786
19.

The Prodrug 4-Chlorokynurenine Causes Ketamine-Like Antidepressant Effects, but Not Side Effects, by NMDA/GlycineB-Site Inhibition.

Zanos P, Piantadosi SC, Wu HQ, Pribut HJ, Dell MJ, Can A, Snodgrass HR, Zarate CA Jr, Schwarcz R, Gould TD.

J Pharmacol Exp Ther. 2015 Oct;355(1):76-85. doi: 10.1124/jpet.115.225664. Epub 2015 Aug 11.

20.

The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders.

Prokai L, Nguyen V, Szarka S, Garg P, Sabnis G, Bimonte-Nelson HA, McLaughlin KJ, Talboom JS, Conrad CD, Shughrue PJ, Gould TD, Brodie A, Merchenthaler I, Koulen P, Prokai-Tatrai K.

Sci Transl Med. 2015 Jul 22;7(297):297ra113. doi: 10.1126/scitranslmed.aab1290.

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