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Structure of ubiquitylated-Rpn10 provides insight into its autoregulation mechanism.

Keren-Kaplan T, Zeev Peters L, Levin-Kravets O, Attali I, Kleifeld O, Shohat N, Artzi S, Zucker O, Pilzer I, Reis N, Glickman MH, Ben-Aroya S, Prag G.

Nat Commun. 2016 Oct 4;7:12960. doi: 10.1038/ncomms12960.


Studying Protein Ubiquitylation in Yeast.

Hovsepian J, Becuwe M, Kleifeld O, Glickman MH, Léon S.

Methods Mol Biol. 2016;1449:117-42. doi: 10.1007/978-1-4939-3756-1_5.


Tuning the proteasome to brighten the end of the journey.

Mayor T, Sharon M, Glickman MH.

Am J Physiol Cell Physiol. 2016 Sep 7:ajpcell.00198.2016. doi: 10.1152/ajpcell.00198.2016. [Epub ahead of print]


UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

Hjerpe R, Bett JS, Keuss MJ, Solovyova A, McWilliams TG, Johnson C, Sahu I, Varghese J, Wood N, Wightman M, Osborne G, Bates GP, Glickman MH, Trost M, Knebel A, Marchesi F, Kurz T.

Cell. 2016 Aug 11;166(4):935-49. doi: 10.1016/j.cell.2016.07.001. Epub 2016 Jul 28.


Bioengineered human acellular vessels for dialysis access in patients with end-stage renal disease: two phase 2 single-arm trials.

Lawson JH, Glickman MH, Ilzecki M, Jakimowicz T, Jaroszynski A, Peden EK, Pilgrim AJ, Prichard HL, Guziewicz M, Przywara S, Szmidt J, Turek J, Witkiewicz W, Zapotoczny N, Zubilewicz T, Niklason LE.

Lancet. 2016 May 14;387(10032):2026-34. doi: 10.1016/S0140-6736(16)00557-2.


HeRO graft versus lower extremity grafts in hemodialysis patients with long standing renal failure.

Glickman MH.

J Vasc Access. 2016 Mar;17 Suppl 1:S30-1. doi: 10.5301/jva.5000531. Epub 2016 Mar 6.


Base-CP proteasome can serve as a platform for stepwise lid formation.

Yu Z, Livnat-Levanon N, Kleifeld O, Mansour W, Nakasone MA, Castaneda CA, Dixon EK, Fushman D, Reis N, Pick E, Glickman MH.

Biosci Rep. 2015 Jan 27;35(3). pii: e00194. doi: 10.1042/BSR20140173.


Prospective multicenter study with a 1-year analysis of a new vascular graft used for early cannulation in patients undergoing hemodialysis.

Glickman MH, Burgess J, Cull D, Roy-Chaudhury P, Schanzer H.

J Vasc Surg. 2015 Aug;62(2):434-41. doi: 10.1016/j.jvs.2015.03.020. Epub 2015 May 4.


The protein quality control machinery regulates its misassembled proteasome subunits.

Peters LZ, Karmon O, David-Kadoch G, Hazan R, Yu T, Glickman MH, Ben-Aroya S.

PLoS Genet. 2015 Apr 28;11(4):e1005178. doi: 10.1371/journal.pgen.1005178. eCollection 2015 Apr.


Chemical synthesis of phosphorylated ubiquitin and diubiquitin exposes positional sensitivities of e1-e2 enzymes and deubiquitinases.

Bondalapati S, Mansour W, Nakasone MA, Maity SK, Glickman MH, Brik A.

Chemistry. 2015 May 11;21(20):7360-4. doi: 10.1002/chem.201500540. Epub 2015 Apr 1.


Arteriovenous graft configuration in hemodialysis: does it matter?

Wuamett JC, Glickman MH.

J Vasc Access. 2015;16 Suppl 9:S78-81. doi: 10.5301/jva.5000356. Epub 2015 Mar 8. Review.


DNA-damage-inducible 1 protein (Ddi1) contains an uncharacteristic ubiquitin-like domain that binds ubiquitin.

Nowicka U, Zhang D, Walker O, Krutauz D, Castañeda CA, Chaturvedi A, Chen TY, Reis N, Glickman MH, Fushman D.

Structure. 2015 Mar 3;23(3):542-57. doi: 10.1016/j.str.2015.01.010. Epub 2015 Feb 19.


Base-CP proteasome can serve as a platform for stepwise lid formation.

Yu Z, Livnat-Levanon N, Kleifeld O, Mansour W, Nakasone MA, Castaneda CA, Dixon EK, Fushman D, Reis N, Pick E, Glickman MH.

Biosci Rep. 2015 Jan 27. [Epub ahead of print]


Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.

Mansour W, Nakasone MA, von Delbrück M, Yu Z, Krutauz D, Reis N, Kleifeld O, Sommer T, Fushman D, Glickman MH.

J Biol Chem. 2015 Feb 20;290(8):4688-704. doi: 10.1074/jbc.M114.568295. Epub 2014 Nov 11.


Patient compliance limits the efforts of quality improvement initiatives on arteriovenous fistula maturation.

Lynch SK, Ahanchi SS, Dexter DJ, Glickman MH, Panneton JM.

J Vasc Surg. 2015 Jan;61(1):184-91. doi: 10.1016/j.jvs.2014.05.095. Epub 2014 Jul 17.


Extended ubiquitin species are protein-based DUB inhibitors.

Krutauz D, Reis N, Nakasone MA, Siman P, Zhang D, Kirkpatrick DS, Gygi SP, Brik A, Fushman D, Glickman MH.

Nat Chem Biol. 2014 Aug;10(8):664-70. doi: 10.1038/nchembio.1574. Epub 2014 Jul 6.


Reversible 26S proteasome disassembly upon mitochondrial stress.

Livnat-Levanon N, Kevei É, Kleifeld O, Krutauz D, Segref A, Rinaldi T, Erpapazoglou Z, Cohen M, Reis N, Hoppe T, Glickman MH.

Cell Rep. 2014 Jun 12;7(5):1371-80. doi: 10.1016/j.celrep.2014.04.030. Epub 2014 May 22.


The Venous Window Needle Guide, a hemodialysis cannulation device for salvage of uncannulatable arteriovenous fistulas.

Jennings WC, Galt SW, Shenoy S, Wang S, Ladenheim ED, Glickman MH, Kathuria P, Browne BJ.

J Vasc Surg. 2014 Oct;60(4):1024-32. doi: 10.1016/j.jvs.2014.04.016. Epub 2014 May 13.


Pathogenesis of human mitochondrial diseases is modulated by reduced activity of the ubiquitin/proteasome system.

Segref A, Kevei É, Pokrzywa W, Schmeisser K, Mansfeld J, Livnat-Levanon N, Ensenauer R, Glickman MH, Ristow M, Hoppe T.

Cell Metab. 2014 Apr 1;19(4):642-52. doi: 10.1016/j.cmet.2014.01.016.


A comparison between the HeRO graft and conventional arteriovenous grafts in hemodialysis patients.

Nassar GM, Glickman MH, McLafferty RB, Croston JK, Zarge JI, Katzman HE, Peden EK, Lawson JH, Martinez JM, Thackeray L.

Semin Dial. 2014 May-Jun;27(3):310-8. doi: 10.1111/sdi.12173. Epub 2014 Jan 15.

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