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Items: 1 to 20 of 104


Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.

Guitart AV, Panagopoulou TI, Villacreces A, Vukovic M, Sepulveda C, Allen L, Carter RN, van de Lagemaat LN, Morgan M, Giles P, Sas Z, Gonzalez MV, Lawson H, Paris J, Edwards-Hicks J, Schaak K, Subramani C, Gezer D, Armesilla-Diaz A, Wills J, Easterbrook A, Coman D, So CW, O'Carroll D, Vernimmen D, Rodrigues NP, Pollard PJ, Morton NM, Finch A, Kranc KR.

J Exp Med. 2017 Mar 6;214(3):719-735. doi: 10.1084/jem.20161087.


IL-10 differentially controls the infiltration of inflammatory macrophages and antigen-presenting cells during inflammation.

Liao CT, Rosas M, Davies LC, Giles PJ, Tyrrell VJ, O'Donnell VB, Topley N, Humphreys IR, Fraser DJ, Jones SA, Taylor PR.

Eur J Immunol. 2016 Sep;46(9):2222-32. doi: 10.1002/eji.201646528. Epub 2016 Jul 28.


Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence.

Bayram-Weston Z, Stone TC, Giles P, Elliston L, Janghra N, Higgs GV, Holmans PA, Dunnett SB, Brooks SP, Jones L.

BMC Genomics. 2015 Dec 21;16:1079. doi: 10.1186/s12864-015-2251-4.


Effects of extended-release niacin with laropiprant in high-risk patients.

HPS2-THRIVE Collaborative Group., Landray MJ, Haynes R, Hopewell JC, Parish S, Aung T, Tomson J, Wallendszus K, Craig M, Jiang L, Collins R, Armitage J.

N Engl J Med. 2014 Jul 17;371(3):203-12. doi: 10.1056/NEJMoa1300955.


mRNA sequencing of novel cell lines from human papillomavirus type-16 related vulval intraepithelial neoplasia: consequences of expression of HPV16 E4 and E5.

Bryant D, Onions T, Raybould R, Flynn Á, Tristram A, Meyrick S, Giles P, Ashelford K, Hibbitts S, Fiander A, Powell N.

J Med Virol. 2014 Sep;86(9):1534-41. doi: 10.1002/jmv.23994.


Identification of a transcriptional signature for the wound healing continuum.

Peake MA, Caley M, Giles PJ, Wall I, Enoch S, Davies LC, Kipling D, Thomas DW, Stephens P.

Wound Repair Regen. 2014 May-Jun;22(3):399-405. doi: 10.1111/wrr.12170.


The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal.

Rosas M, Davies LC, Giles PJ, Liao CT, Kharfan B, Stone TC, O'Donnell VB, Fraser DJ, Jones SA, Taylor PR.

Science. 2014 May 9;344(6184):645-8. doi: 10.1126/science.1251414.


Study design of ASPirin in Reducing Events in the Elderly (ASPREE): a randomized, controlled trial.

ASPREE Investigator Group..

Contemp Clin Trials. 2013 Nov;36(2):555-64. doi: 10.1016/j.cct.2013.09.014.


Time trends of gender-based differences in lipid goal attainments during secondary prevention of coronary artery disease: results of a 5-year survey.

Singh M, Chin SH, Crothers D, Giles P, Al-Allaf K, Khan JM.

Am J Ther. 2013 Nov-Dec;20(6):613-7. doi: 10.1097/MJT.0b013e31824c3e8c.


Suboccipital decompression enhances heart rate variability indices of cardiac control in healthy subjects.

Giles PD, Hensel KL, Pacchia CF, Smith ML.

J Altern Complement Med. 2013 Feb;19(2):92-6. doi: 10.1089/acm.2011.0031.


Early transcriptional changes linked to naturally occurring Huntington's disease mutations in neural derivatives of human embryonic stem cells.

Feyeux M, Bourgois-Rocha F, Redfern A, Giles P, Lefort N, Aubert S, Bonnefond C, Bugi A, Ruiz M, Deglon N, Jones L, Peschanski M, Allen ND, Perrier AL.

Hum Mol Genet. 2012 Sep 1;21(17):3883-95. doi: 10.1093/hmg/dds216.


Benefits and safety of long-term fenofibrate therapy in people with type 2 diabetes and renal impairment: the FIELD Study.

Ting RD, Keech AC, Drury PL, Donoghoe MW, Hedley J, Jenkins AJ, Davis TM, Lehto S, Celermajer D, Simes RJ, Rajamani K, Stanton K; FIELD Study Investigators..

Diabetes Care. 2012 Feb;35(2):218-25. doi: 10.2337/dc11-1109.


Pharmacokinetics of vandetanib: three phase I studies in healthy subjects.

Martin P, Oliver S, Kennedy SJ, Partridge E, Hutchison M, Clarke D, Giles P.

Clin Ther. 2012 Jan;34(1):221-37. doi: 10.1016/j.clinthera.2011.11.011.


Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of Huntington's disease.

Giles P, Elliston L, Higgs GV, Brooks SP, Dunnett SB, Jones L.

Brain Res Bull. 2012 Jun 1;88(2-3):199-209. doi: 10.1016/j.brainresbull.2011.10.001.


Nurse education the key to managing diabetes more effectively.

Giles P.

Nurs N Z. 2011 Mar;17(2):22-3. No abstract available.


'Young' oral fibroblasts are geno/phenotypically distinct.

Enoch S, Peake MA, Wall I, Davies L, Farrier J, Giles P, Kipling D, Price P, Moseley R, Thomas D, Stephens P.

J Dent Res. 2010 Dec;89(12):1407-13. doi: 10.1177/0022034510377796.


Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial.

Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group., Armitage J, Bowman L, Wallendszus K, Bulbulia R, Rahimi K, Haynes R, Parish S, Peto R, Collins R.

Lancet. 2010 Nov 13;376(9753):1658-69. doi: 10.1016/S0140-6736(10)60310-8. Erratum in: Lancet. 2011 Jan 8;377(9760):126.


Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial.

Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group., Armitage JM, Bowman L, Clarke RJ, Wallendszus K, Bulbulia R, Rahimi K, Haynes R, Parish S, Sleight P, Peto R, Collins R.

JAMA. 2010 Jun 23;303(24):2486-94. doi: 10.1001/jama.2010.840.


VFDs can cut costs and improve control.

Giles P.

Health Estate. 2010 May;64(5):29-31.


Controlling lipids in a high-risk population with documented coronary artery disease for secondary prevention: are we doing enough?

Singh M, Chin SH, Giles PD, Crothers D, Al-Allaf K, Khan JM.

Eur J Cardiovasc Prev Rehabil. 2010 Oct;17(5):556-61. doi: 10.1097/HJR.0b013e328338978e.


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