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Items: 1 to 20 of 53


High Dose Gamma Radiation Selectively Reduces GABAA-slow Inhibition.

Dagne BA, Sunay MK, Cayla NS, Ouyang YB, Knox SJ, Giffard RG, Adler JR, Maciver B.

Cureus. 2017 Mar 4;9(3):e1076. doi: 10.7759/cureus.1076.


Gpr124 is essential for blood-brain barrier integrity in central nervous system disease.

Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M, Kosinski C, Zhang JJ, Mah AT, Xu L, Li L, Gholamin S, Reyes TF, Li R, Kuhnert F, Han X, Yuan J, Chiou SH, Brettman AD, Daly L, Corney DC, Cheshier SH, Shortliffe LD, Wu X, Snyder M, Chan P, Giffard RG, Chang HY, Andreasson K, Kuo CJ.

Nat Med. 2017 Apr;23(4):450-460. doi: 10.1038/nm.4309. Epub 2017 Mar 13.


Distinct Effects of miR-210 Reduction on Neurogenesis: Increased Neuronal Survival of Inflammation But Reduced Proliferation Associated with Mitochondrial Enhancement.

Voloboueva LA, Sun X, Xu L, Ouyang YB, Giffard RG.

J Neurosci. 2017 Mar 15;37(11):3072-3084. doi: 10.1523/JNEUROSCI.1777-16.2017. Epub 2017 Feb 10.


Astrocytes Protect against Isoflurane Neurotoxicity by Buffering pro-brain-derived Neurotrophic Factor.

Stary CM, Sun X, Giffard RG.

Anesthesiology. 2015 Oct;123(4):810-9. doi: 10.1097/ALN.0000000000000824.


Physiologically normal 5% O2 supports neuronal differentiation and resistance to inflammatory injury in neural stem cell cultures.

Sun X, Voloboueva LA, Stary CM, Giffard RG.

J Neurosci Res. 2015 Nov;93(11):1703-12. doi: 10.1002/jnr.23615. Epub 2015 Jul 3.


IL-4 Is Required for Sex Differences in Vulnerability to Focal Ischemia in Mice.

Xiong X, Xu L, Wei L, White RE, Ouyang YB, Giffard RG.

Stroke. 2015 Aug;46(8):2271-6. doi: 10.1161/STROKEAHA.115.008897. Epub 2015 Jun 30.


MicroRNA-200c contributes to injury from transient focal cerebral ischemia by targeting Reelin.

Stary CM, Xu L, Sun X, Ouyang YB, White RE, Leong J, Li J, Xiong X, Giffard RG.

Stroke. 2015 Feb;46(2):551-6. doi: 10.1161/STROKEAHA.114.007041. Epub 2015 Jan 20.


Post-stroke treatment with miR-181 antagomir reduces injury and improves long-term behavioral recovery in mice after focal cerebral ischemia.

Xu LJ, Ouyang YB, Xiong X, Stary CM, Giffard RG.

Exp Neurol. 2015 Feb;264:1-7. doi: 10.1016/j.expneurol.2014.11.007. Epub 2014 Nov 26.


Role of Astrocytes in Delayed Neuronal Death: GLT-1 and its Novel Regulation by MicroRNAs.

Ouyang YB, Xu L, Liu S, Giffard RG.

Adv Neurobiol. 2014;11:171-88. doi: 10.1007/978-3-319-08894-5_9.


Advances in astrocyte-targeted approaches for stroke therapy: an emerging role for mitochondria and microRNAS.

Stary CM, Giffard RG.

Neurochem Res. 2015 Feb;40(2):301-7. doi: 10.1007/s11064-014-1373-4. Epub 2014 Jul 4. Review.


Overexpression of heat shock protein 72 attenuates NF-κB activation using a combination of regulatory mechanisms in microglia.

Sheppard PW, Sun X, Khammash M, Giffard RG.

PLoS Comput Biol. 2014 Feb 6;10(2):e1003471. doi: 10.1371/journal.pcbi.1003471. eCollection 2014 Feb.


MicroRNAs affect BCL-2 family proteins in the setting of cerebral ischemia.

Ouyang YB, Giffard RG.

Neurochem Int. 2014 Nov;77:2-8. doi: 10.1016/j.neuint.2013.12.006. Epub 2013 Dec 25. Review.


The use of microRNAs to modulate redox and immune response to stroke.

Ouyang YB, Stary CM, White RE, Giffard RG.

Antioxid Redox Signal. 2015 Jan 10;22(2):187-202. doi: 10.1089/ars.2013.5757. Review.


MicroRNAs regulate the chaperone network in cerebral ischemia.

Ouyang YB, Giffard RG.

Transl Stroke Res. 2013 Dec;4(6):693-703. doi: 10.1007/s12975-013-0280-3. Epub 2013 Aug 17. Review.


Neuroprotection by astrocytes in brain ischemia: importance of microRNAs.

Ouyang YB, Xu L, Yue S, Liu S, Giffard RG.

Neurosci Lett. 2014 Apr 17;565:53-8. doi: 10.1016/j.neulet.2013.11.015. Epub 2013 Nov 19. Review.


The future of molecular chaperones and beyond.

Giffard RG, Macario AJ, de Macario EC.

J Clin Invest. 2013 Aug;123(8):3206-8.


Astrocyte-enriched miR-29a targets PUMA and reduces neuronal vulnerability to forebrain ischemia.

Ouyang YB, Xu L, Lu Y, Sun X, Yue S, Xiong XX, Giffard RG.

Glia. 2013 Nov;61(11):1784-94. doi: 10.1002/glia.22556. Epub 2013 Aug 30.


Inhibition of microRNA-181 reduces forebrain ischemia-induced neuronal loss.

Moon JM, Xu L, Giffard RG.

J Cereb Blood Flow Metab. 2013 Dec;33(12):1976-82. doi: 10.1038/jcbfm.2013.157. Epub 2013 Sep 4.


Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.

Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW, Ma D, Orser BA, Planel E, Slikker W Jr, Soriano SG, Stratmann G, Vutskits L, Xie Z, Hemmings HC Jr.

Br J Anaesth. 2013 Aug;111(2):143-51. doi: 10.1093/bja/aet177. Epub 2013 May 30.


Selective activation of protein kinase C∊ in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice.

Sun X, Budas GR, Xu L, Barreto GE, Mochly-Rosen D, Giffard RG.

J Neurosci Res. 2013 Jun;91(6):799-807. doi: 10.1002/jnr.23186. Epub 2013 Feb 21.

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