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Items: 1 to 20 of 679


Mitogen-Activated Protein Kinases as Therapeutic Targets for Asthma.

Khorasanizadeh M, Eskian M, Gelfand EW, Rezaei N.

Pharmacol Ther. 2017 Feb 13. pii: S0163-7258(17)30038-4. doi: 10.1016/j.pharmthera.2017.02.024. [Epub ahead of print] Review.


Dysregulation of Metabolic Pathways in a Mouse Model of Allergic Asthma.

Quinn KD, Schedel M, Nkrumah-Elie Y, Joetham A, Armstrong M, Cruickshank-Quinn C, Reisdorph R, Gelfand EW, Reisdorph N.

Allergy. 2017 Feb 18. doi: 10.1111/all.13144. [Epub ahead of print]


IL-23 Is Essential for the Development of Elastase-Induced Pulmonary Inflammation and Emphysema.

Fujii U, Miyahara N, Taniguchi A, Waseda K, Morichika D, Kurimoto E, Koga H, Kataoka M, Gelfand EW, Cua DJ, Yoshimura A, Tanimoto M, Kanehiro A.

Am J Respir Cell Mol Biol. 2016 Nov;55(5):697-707.


Inducible and naturally occurring regulatory T cells enhance lung allergic responses through divergent transcriptional pathways.

Joetham A, Schedel M, O'Connor BP, Kim S, Takeda K, Abbott J, Gelfand EW.

J Allergy Clin Immunol. 2016 Aug 16. pii: S0091-6749(16)30792-8. doi: 10.1016/j.jaci.2016.06.051. [Epub ahead of print]


In Vivo Assessment of Airway Function in the Mouse Model.

Dakhama A, Gelfand EW.

Methods Mol Biol. 2016;1442:219-30. doi: 10.1007/978-1-4939-3687-8_16.


Immunomodulatory Effects of Ambroxol on Airway Hyperresponsiveness and Inflammation.

Takeda K, Miyahara N, Matsubara S, Taube C, Kitamura K, Hirano A, Tanimoto M, Gelfand EW.

Immune Netw. 2016 Jun;16(3):165-75. doi: 10.4110/in.2016.16.3.165.


Combined blockade of the histamine H1 and H4 receptor suppresses peanut-induced intestinal anaphylaxis by regulating dendritic cell function.

Wang M, Han J, Domenico J, Shin YS, Jia Y, Gelfand EW.

Allergy. 2016 Nov;71(11):1561-1574. doi: 10.1111/all.12904.


Loss of B Cells in Patients with Heterozygous Mutations in IKAROS.

Kuehn HS, Boisson B, Cunningham-Rundles C, Reichenbach J, Stray-Pedersen A, Gelfand EW, Maffucci P, Pierce KR, Abbott JK, Voelkerding KV, South ST, Augustine NH, Bush JS, Dolen WK, Wray BB, Itan Y, Cobat A, Sorte HS, Ganesan S, Prader S, Martins TB, Lawrence MG, Orange JS, Calvo KR, Niemela JE, Casanova JL, Fleisher TA, Hill HR, Kumánovics A, Conley ME, Rosenzweig SD.

N Engl J Med. 2016 Mar 17;374(11):1032-43. doi: 10.1056/NEJMoa1512234.


1,25D3 prevents CD8(+)Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter.

Schedel M, Jia Y, Michel S, Takeda K, Domenico J, Joetham A, Ning F, Strand M, Han J, Wang M, Lucas JJ, Vogelberg C, Kabesch M, O'Connor BP, Gelfand EW.

Nat Commun. 2016 Jan 11;7:10213. doi: 10.1038/ncomms10213.


Late Onset Hypomorphic RAG2 Deficiency Presentation with Fatal Vaccine-Strain VZV Infection.

Dutmer CM, Asturias EJ, Smith C, Dishop MK, Schmid DS, Bellini WJ, Tirosh I, Lee YN, Notarangelo LD, Gelfand EW.

J Clin Immunol. 2015 Nov;35(8):754-60. doi: 10.1007/s10875-015-0207-8.


Contrasting roles for the receptor for advanced glycation end-products on structural cells in allergic airway inflammation vs. airway hyperresponsiveness.

Taniguchi A, Miyahara N, Waseda K, Kurimoto E, Fujii U, Tanimoto Y, Kataoka M, Yamamoto Y, Gelfand EW, Yamamoto H, Tanimoto M, Kanehiro A.

Am J Physiol Lung Cell Mol Physiol. 2015 Oct 15;309(8):L789-800. doi: 10.1152/ajplung.00087.2015.


Primary Immunodeficiency Masquerading as Allergic Disease.

Chan SK, Gelfand EW.

Immunol Allergy Clin North Am. 2015 Nov;35(4):767-78. doi: 10.1016/j.iac.2015.07.008. Review.


Common Variable Immunodeficiency: Diagnosis, Management, and Treatment.

Abbott JK, Gelfand EW.

Immunol Allergy Clin North Am. 2015 Nov;35(4):637-58. doi: 10.1016/j.iac.2015.07.009. Review.


A Toddler With Rash, Encephalopathy, and Hemolytic Anemia.

Smith C, Dutmer C, Schmid DS, Dishop MK, Bellini WJ, Gelfand EW, Asturias EJ.

J Pediatric Infect Dis Soc. 2015 Dec;4(4):376-80. doi: 10.1093/jpids/piv032. No abstract available.


Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings.

Meltzer LJ, Faino A, Szefler SJ, Strand M, Gelfand EW, Beebe DW.

Pediatr Pulmonol. 2015 Dec;50(12):1360-7. doi: 10.1002/ppul.23179.


The other side of asthma: Steroid-refractory disease in the absence of TH2-mediated inflammation.

Gelfand EW, Alam R.

J Allergy Clin Immunol. 2015 May;135(5):1196-8. doi: 10.1016/j.jaci.2015.01.032. No abstract available.


Eosinophils contribute to the resolution of lung-allergic responses following repeated allergen challenge.

Takeda K, Shiraishi Y, Ashino S, Han J, Jia Y, Wang M, Lee NA, Lee JJ, Gelfand EW.

J Allergy Clin Immunol. 2015 Feb;135(2):451-60. doi: 10.1016/j.jaci.2014.08.014.


Emphysema requires the receptor for advanced glycation end-products triggering on structural cells.

Waseda K, Miyahara N, Taniguchi A, Kurimoto E, Ikeda G, Koga H, Fujii U, Yamamoto Y, Gelfand EW, Yamamoto H, Tanimoto M, Kanehiro A.

Am J Respir Cell Mol Biol. 2015 Apr;52(4):482-91. doi: 10.1165/rcmb.2014-0027OC.


Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States.

Kwan A, Abraham RS, Currier R, Brower A, Andruszewski K, Abbott JK, Baker M, Ballow M, Bartoshesky LE, Bonilla FA, Brokopp C, Brooks E, Caggana M, Celestin J, Church JA, Comeau AM, Connelly JA, Cowan MJ, Cunningham-Rundles C, Dasu T, Dave N, De La Morena MT, Duffner U, Fong CT, Forbes L, Freedenberg D, Gelfand EW, Hale JE, Hanson IC, Hay BN, Hu D, Infante A, Johnson D, Kapoor N, Kay DM, Kohn DB, Lee R, Lehman H, Lin Z, Lorey F, Abdel-Mageed A, Manning A, McGhee S, Moore TB, Naides SJ, Notarangelo LD, Orange JS, Pai SY, Porteus M, Rodriguez R, Romberg N, Routes J, Ruehle M, Rubenstein A, Saavedra-Matiz CA, Scott G, Scott PM, Secord E, Seroogy C, Shearer WT, Siegel S, Silvers SK, Stiehm ER, Sugerman RW, Sullivan JL, Tanksley S, Tierce ML 4th, Verbsky J, Vogel B, Walker R, Walkovich K, Walter JE, Wasserman RL, Watson MS, Weinberg GA, Weiner LB, Wood H, Yates AB, Puck JM, Bonagura VR.

JAMA. 2014 Aug 20;312(7):729-38. doi: 10.1001/jama.2014.9132. Erratum in: JAMA. 2014 Nov 26;312(20):2169. Bonagura, Vincent R [Added].


JNK2 regulates the functional plasticity of naturally occurring T regulatory cells and the enhancement of lung allergic responses.

Joetham A, Schedel M, Takeda K, Jia Y, Ashino S, Dakhama A, Lluis A, Okamoto M, Gelfand EW.

J Immunol. 2014 Sep 1;193(5):2238-47. doi: 10.4049/jimmunol.1400604.

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