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Items: 1 to 20 of 27


Scriptaid enhances skeletal muscle insulin action and cardiac function in obese mice.

Gaur V, Connor T, Venardos K, Henstridge DC, Martin SD, Swinton C, Morrison S, Aston-Mourney K, Gehrig SM, van Ewijk R, Lynch GS, Febbraio MA, Steinberg GR, Hargreaves M, Walder KR, McGee SL.

Diabetes Obes Metab. 2017 Feb 2. doi: 10.1111/dom.12896. [Epub ahead of print]


Skeletal muscle-specific overexpression of IGFBP-2 promotes a slower muscle phenotype in healthy but not dystrophic mdx mice and does not affect the dystrophic pathology.

Swiderski K, Martins KJ, Chee A, Trieu J, Naim T, Gehrig SM, Baum DM, Brenmoehl J, Chau L, Koopman R, Gregorevic P, Metzger F, Hoeflich A, Lynch GS.

Growth Horm IGF Res. 2016 Oct - Dec;30-31:1-10. doi: 10.1016/j.ghir.2016.07.002. Epub 2016 Jul 29.


BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle.

Kennedy TL, Swiderski K, Murphy KT, Gehrig SM, Curl CL, Chandramouli C, Febbraio MA, Delbridge LM, Koopman R, Lynch GS.

Am J Pathol. 2016 Dec;186(12):3246-3260. doi: 10.1016/j.ajpath.2016.08.008. Epub 2016 Oct 14.


Exercise effects in Huntington disease.

Frese S, Petersen JA, Ligon-Auer M, Mueller SM, Mihaylova V, Gehrig SM, Kana V, Rushing EJ, Unterburger E, Kägi G, Burgunder JM, Toigo M, Jung HH.

J Neurol. 2017 Jan;264(1):32-39. doi: 10.1007/s00415-016-8310-1. Epub 2016 Oct 17.


Altered skeletal muscle (mitochondrial) properties in patients with mitochondrial DNA single deletion myopathy.

Gehrig SM, Mihaylova V, Frese S, Mueller SM, Ligon-Auer M, Spengler CM, Petersen JA, Lundby C, Jung HH.

Orphanet J Rare Dis. 2016 Jul 29;11(1):105. doi: 10.1186/s13023-016-0488-x.


FHL1 reduces dystrophy in transgenic mice overexpressing FSHD muscular dystrophy region gene 1 (FRG1).

Feeney SJ, McGrath MJ, Sriratana A, Gehrig SM, Lynch GS, D'Arcy CE, Price JT, McLean CA, Tupler R, Mitchell CA.

PLoS One. 2015 Feb 19;10(2):e0117665. doi: 10.1371/journal.pone.0117665. eCollection 2015 Feb 19.


Dysfunctional muscle and liver glycogen metabolism in mdx dystrophic mice.

Stapleton DI, Lau X, Flores M, Trieu J, Gehrig SM, Chee A, Naim T, Lynch GS, Koopman R.

PLoS One. 2014 Mar 13;9(3):e91514. doi: 10.1371/journal.pone.0091514. eCollection 2014 Mar 13.


Tranilast administration reduces fibrosis and improves fatigue resistance in muscles of mdx dystrophic mice.

Swiderski K, Todorov M, Gehrig SM, Naim T, Chee A, Stapleton DI, Koopman R, Lynch GS.

Fibrogenesis Tissue Repair. 2014 Jan 30;7(1):1. doi: 10.1186/1755-1536-7-1.


Alterations in Notch signalling in skeletal muscles from mdx and dko dystrophic mice and patients with Duchenne muscular dystrophy.

Church JE, Trieu J, Chee A, Naim T, Gehrig SM, Lamon S, Angelini C, Russell AP, Lynch GS.

Exp Physiol. 2014 Apr;99(4):675-87. doi: 10.1113/expphysiol.2013.077255. Epub 2014 Jan 17.


Identification of FHL1 as a therapeutic target for Duchenne muscular dystrophy.

D'Arcy CE, Feeney SJ, McLean CA, Gehrig SM, Lynch GS, Smith JE, Cowling BS, Mitchell CA, McGrath MJ.

Hum Mol Genet. 2014 Feb 1;23(3):618-36. doi: 10.1093/hmg/ddt449. Epub 2013 Sep 18.


Intramuscular administration of PEGylated IGF-I improves skeletal muscle regeneration after myotoxic injury.

Martins KJ, Gehrig SM, Naim T, Saenger S, Baum D, Metzger F, Lynch GS.

Growth Horm IGF Res. 2013 Aug;23(4):128-33. doi: 10.1016/j.ghir.2013.03.002. Epub 2013 Apr 19.


Multiday acute sodium bicarbonate intake improves endurance capacity and reduces acidosis in men.

Mueller SM, Gehrig SM, Frese S, Wagner CA, Boutellier U, Toigo M.

J Int Soc Sports Nutr. 2013 Mar 26;10(1):16. doi: 10.1186/1550-2783-10-16.


Hsp72 preserves muscle function and slows progression of severe muscular dystrophy.

Gehrig SM, van der Poel C, Sayer TA, Schertzer JD, Henstridge DC, Church JE, Lamon S, Russell AP, Davies KE, Febbraio MA, Lynch GS.

Nature. 2012 Apr 4;484(7394):394-8. doi: 10.1038/nature10980.


Therapeutic potential of PEGylated insulin-like growth factor I for skeletal muscle disease evaluated in two murine models of muscular dystrophy.

Gehrig SM, van der Poel C, Hoeflich A, Naim T, Lynch GS, Metzger F.

Growth Horm IGF Res. 2012 Apr;22(2):69-75. doi: 10.1016/j.ghir.2012.02.004. Epub 2012 Mar 15.


Early functional muscle regeneration after myotoxic injury in mice is unaffected by nNOS absence.

Church JE, Gehrig SM, Chee A, Naim T, Trieu J, McConell GK, Lynch GS.

Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1358-66. doi: 10.1152/ajpregu.00096.2011. Epub 2011 Aug 17.


Emerging drugs for treating skeletal muscle injury and promoting muscle repair.

Gehrig SM, Lynch GS.

Expert Opin Emerg Drugs. 2011 Mar;16(1):163-82. doi: 10.1517/14728214.2010.524743. Epub 2011 Feb 16. Review.


Chronic formoterol administration reduces cardiac mitochondrial protein synthesis and oxidative capacity in mice.

Léger B, Koopman R, Walrand S, Gehrig SM, Murphy KT, Lynch GS.

Int J Cardiol. 2011 Jan 21;146(2):270-2. doi: 10.1016/j.ijcard.2010.10.078. Epub 2010 Nov 20. No abstract available.


Cellular mechanisms underlying temporal changes in skeletal muscle protein synthesis and breakdown during chronic {beta}-adrenoceptor stimulation in mice.

Koopman R, Gehrig SM, Léger B, Trieu J, Walrand S, Murphy KT, Lynch GS.

J Physiol. 2010 Dec 1;588(Pt 23):4811-23. doi: 10.1113/jphysiol.2010.196725. Epub 2010 Oct 11.


Making fast-twitch dystrophic muscles bigger protects them from contraction injury and attenuates the dystrophic pathology.

Gehrig SM, Koopman R, Naim T, Tjoakarfa C, Lynch GS.

Am J Pathol. 2010 Jan;176(1):29-33. doi: 10.2353/ajpath.2010.090760. Epub 2009 Dec 3.


Adaptive divergence in experimental populations of Pseudomonas fluorescens. IV. Genetic constraints guide evolutionary trajectories in a parallel adaptive radiation.

McDonald MJ, Gehrig SM, Meintjes PL, Zhang XX, Rainey PB.

Genetics. 2009 Nov;183(3):1041-53. doi: 10.1534/genetics.109.107110. Epub 2009 Aug 24.

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