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Items: 8

1.

Position-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells.

Ajith S, Gazzara MR, Cole BS, Shankarling G, Martinez NM, Mallory MJ, Lynch KW.

RNA Biol. 2016 Jun 2;13(6):569-81. doi: 10.1080/15476286.2016.1176663.

2.

A new view of transcriptome complexity and regulation through the lens of local splicing variations.

Vaquero-Garcia J, Barrera A, Gazzara MR, González-Vallinas J, Lahens NF, Hogenesch JB, Lynch KW, Barash Y.

Elife. 2016 Feb 1;5:e11752. doi: 10.7554/eLife.11752.

3.

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy.

Sotillo E, Barrett DM, Black KL, Bagashev A, Oldridge D, Wu G, Sussman R, Lanauze C, Ruella M, Gazzara MR, Martinez NM, Harrington CT, Chung EY, Perazzelli J, Hofmann TJ, Maude SL, Raman P, Barrera A, Gill S, Lacey SF, Melenhorst JJ, Allman D, Jacoby E, Fry T, Mackall C, Barash Y, Lynch KW, Maris JM, Grupp SA, Thomas-Tikhonenko A.

Cancer Discov. 2015 Dec;5(12):1282-95. doi: 10.1158/2159-8290.CD-15-1020.

4.

Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation.

Martinez NM, Agosto L, Qiu J, Mallory MJ, Gazzara MR, Barash Y, Fu XD, Lynch KW.

Genes Dev. 2015 Oct 1;29(19):2054-66. doi: 10.1101/gad.267245.115.

5.

Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling.

Mallory MJ, Allon SJ, Qiu J, Gazzara MR, Tapescu I, Martinez NM, Fu XD, Lynch KW.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):E2139-48. doi: 10.1073/pnas.1423695112.

6.

In silico to in vivo splicing analysis using splicing code models.

Gazzara MR, Vaquero-Garcia J, Lynch KW, Barash Y.

Methods. 2014 May 1;67(1):3-12. doi: 10.1016/j.ymeth.2013.11.006.

7.

Contrasting dynamics of a mutator allele in asexual populations of differing size.

Raynes Y, Gazzara MR, Sniegowski PD.

Evolution. 2012 Jul;66(7):2329-34. doi: 10.1111/j.1558-5646.2011.01577.x.

8.

Mutator dynamics in sexual and asexual experimental populations of yeast.

Raynes Y, Gazzara MR, Sniegowski PD.

BMC Evol Biol. 2011 Jun 7;11:158. doi: 10.1186/1471-2148-11-158.

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