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Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.

Stoeck A, Lejnine S, Truong A, Pan L, Wang H, Zang C, Yuan J, Ware C, MacLean J, Garrett-Engele PW, Kluk M, Laskey J, Haines BB, Moskaluk C, Zawel L, Fawell S, Gilliland G, Zhang T, Kremer BE, Knoechel B, Bernstein BE, Pear WS, Liu XS, Aster JC, Sathyanarayanan S.

Cancer Discov. 2014 Oct;4(10):1154-67. doi: 10.1158/2159-8290.CD-13-0830.


Circulating miR-122 as a potential biomarker of liver disease.

Laterza OF, Scott MG, Garrett-Engele PW, Korenblat KM, Lockwood CM.

Biomark Med. 2013 Apr;7(2):205-10. doi: 10.2217/bmm.12.107.


A quantitative atlas of polyadenylation in five mammals.

Derti A, Garrett-Engele P, Macisaac KD, Stevens RC, Sriram S, Chen R, Rohl CA, Johnson JM, Babak T.

Genome Res. 2012 Jun;22(6):1173-83. doi: 10.1101/gr.132563.111.


Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation.

Babak T, Garrett-Engele P, Armour CD, Raymond CK, Keller MP, Chen R, Rohl CA, Johnson JM, Attie AD, Fraser HB, Schadt EE.

BMC Genomics. 2010 Aug 13;11:473. doi: 10.1186/1471-2164-11-473.


Plasma MicroRNAs as sensitive and specific biomarkers of tissue injury.

Laterza OF, Lim L, Garrett-Engele PW, Vlasakova K, Muniappa N, Tanaka WK, Johnson JM, Sina JF, Fare TL, Sistare FD, Glaab WE.

Clin Chem. 2009 Nov;55(11):1977-83. doi: 10.1373/clinchem.2009.131797.


ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected].

Castle JC, Hara Y, Raymond CK, Garrett-Engele P, Ohwaki K, Kan Z, Kusunoki J, Johnson JM.

PLoS One. 2009;4(2):e4369. doi: 10.1371/journal.pone.0004369. Erratum in: PLoS One. 2009; 4(2) doi:10.1371/annotation/c921dfce-9702-4632-abbe-f13d62fdfde0.


MicroRNA targeting specificity in mammals: determinants beyond seed pairing.

Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP.

Mol Cell. 2007 Jul 6;27(1):91-105.


PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6).

Cheung YF, Kan Z, Garrett-Engele P, Gall I, Murdoch H, Baillie GS, Camargo LM, Johnson JM, Houslay MD, Castle JC.

J Pharmacol Exp Ther. 2007 Aug;322(2):600-9.


Simple, quantitative primer-extension PCR assay for direct monitoring of microRNAs and short-interfering RNAs.

Raymond CK, Roberts BS, Garrett-Engele P, Lim LP, Johnson JM.

RNA. 2005 Nov;11(11):1737-44.


Evolutionarily conserved and diverged alternative splicing events show different expression and functional profiles.

Kan Z, Garrett-Engele PW, Johnson JM, Castle JC.

Nucleic Acids Res. 2005 Sep 29;33(17):5659-66.


Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs.

Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM.

Nature. 2005 Feb 17;433(7027):769-73.


A comprehensive transcript index of the human genome generated using microarrays and computational approaches.

Schadt EE, Edwards SW, GuhaThakurta D, Holder D, Ying L, Svetnik V, Leonardson A, Hart KW, Russell A, Li G, Cavet G, Castle J, McDonagh P, Kan Z, Chen R, Kasarskis A, Margarint M, Caceres RM, Johnson JM, Armour CD, Garrett-Engele PW, Tsinoremas NF, Shoemaker DD.

Genome Biol. 2004;5(10):R73.


Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.

Raymond CK, Castle J, Garrett-Engele P, Armour CD, Kan Z, Tsinoremas N, Johnson JM.

J Biol Chem. 2004 Oct 29;279(44):46234-41.


Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes.

Lum PY, Armour CD, Stepaniants SB, Cavet G, Wolf MK, Butler JS, Hinshaw JC, Garnier P, Prestwich GD, Leonardson A, Garrett-Engele P, Rush CM, Bard M, Schimmack G, Phillips JW, Roberts CJ, Shoemaker DD.

Cell. 2004 Jan 9;116(1):121-37.


Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.

Johnson JM, Castle J, Garrett-Engele P, Kan Z, Loerch PM, Armour CD, Santos R, Schadt EE, Stoughton R, Shoemaker DD.

Science. 2003 Dec 19;302(5653):2141-4.


Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing.

Castle J, Garrett-Engele P, Armour CD, Duenwald SJ, Loerch PM, Meyer MR, Schadt EE, Stoughton R, Parrish ML, Shoemaker DD, Johnson JM.

Genome Biol. 2003;4(10):R66.


Parallel analysis of tagged deletion mutants efficiently identifies genes involved in endoplasmic reticulum biogenesis.

Wright R, Parrish ML, Cadera E, Larson L, Matson CK, Garrett-Engele P, Armour C, Lum PY, Shoemaker DD.

Yeast. 2003 Jul 30;20(10):881-92.


Experimental annotation of the human genome using microarray technology.

Shoemaker DD, Schadt EE, Armour CD, He YD, Garrett-Engele P, McDonagh PD, Loerch PM, Leonardson A, Lum PY, Cavet G, Wu LF, Altschuler SJ, Edwards S, King J, Tsang JS, Schimmack G, Schelter JM, Koch J, Ziman M, Marton MJ, Li B, Cundiff P, Ward T, Castle J, Krolewski M, Meyer MR, Mao M, Burchard J, Kidd MJ, Dai H, Phillips JW, Linsley PS, Stoughton R, Scherer S, Boguski MS.

Nature. 2001 Feb 15;409(6822):922-7.


A methylated Neurospora 5S rRNA pseudogene contains a transposable element inactivated by repeat-induced point mutation.

Margolin BS, Garrett-Engele PW, Stevens JN, Fritz DY, Garrett-Engele C, Metzenberg RL, Selker EU.

Genetics. 1998 Aug;149(4):1787-97.


Temperature-induced expression of yeast FKS2 is under the dual control of protein kinase C and calcineurin.

Zhao C, Jung US, Garrett-Engele P, Roe T, Cyert MS, Levin DE.

Mol Cell Biol. 1998 Feb;18(2):1013-22.

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