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Items: 1 to 20 of 33

1.

Molecular cytogenetic (FISH) and genome analysis of diploid wheatgrasses and their phylogenetic relationship.

Linc G, Gaál E, Molnár I, Icsó D, Badaeva E, Molnár-Láng M.

PLoS One. 2017 Mar 9;12(3):e0173623. doi: 10.1371/journal.pone.0173623. eCollection 2017.

2.

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.

van 't Hof FN, Ruigrok YM, Lee CH, Ripke S, Anderson G, de Andrade M, Baas AF, Blankensteijn JD, Böttinger EP, Bown MJ, Broderick J, Bijlenga P, Carrell DS, Crawford DC, Crosslin DR, Ebeling C, Eriksson JG, Fornage M, Foroud T, von Und Zu Fraunberg M, Friedrich CM, Gaál EI, Gottesman O, Guo DC, Harrison SC, Hernesniemi J, Hofman A, Inoue I, Jääskeläinen JE, Jones GT, Kiemeney LA, Kivisaari R, Ko N, Koskinen S, Kubo M, Kullo IJ, Kuivaniemi H, Kurki MI, Laakso A, Lai D, Leal SM, Lehto H, LeMaire SA, Low SK, Malinowski J, McCarty CA, Milewicz DM, Mosley TH, Nakamura Y, Nakaoka H, Niemelä M, Pacheco J, Peissig PL, Pera J, Rasmussen-Torvik L, Ritchie MD, Rivadeneira F, van Rij AM, Santos-Cortez RL, Saratzis A, Slowik A, Takahashi A, Tromp G, Uitterlinden AG, Verma SS, Vermeulen SH, Wang GT; Aneurysm Consortium; Vascular Research Consortium of New Zealand, Han B, Rinkel GJ, de Bakker PI.

J Am Heart Assoc. 2016 Jul 14;5(7). pii: e002603. doi: 10.1161/JAHA.115.002603.

3.

Tailoring the physicochemical properties of core-crosslinked polymeric micelles for pharmaceutical applications.

Hu Q, Rijcken CJ, van Gaal E, Brundel P, Kostkova H, Etrych T, Weber B, Barz M, Kiessling F, Prakash J, Storm G, Hennink WE, Lammers T.

J Control Release. 2016 Dec 28;244(Pt B):314-325. doi: 10.1016/j.jconrel.2016.07.012. Epub 2016 Jul 9.

PMID:
27401327
4.

Nonelective surgery at night and in-hospital mortality: Prospective observational data from the European Surgical Outcomes Study.

van Zaane B, van Klei WA, Buhre WF, Bauer P, Boerma EC, Hoeft A, Metnitz P, Moreno RP, Pearse R, Pelosi P, Sander M, Vallet B, Pettilä V, Vincent JL, Rhodes A; European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology.

Eur J Anaesthesiol. 2015 Jul;32(7):477-85. doi: 10.1097/EJA.0000000000000256.

PMID:
26001104
5.

A novel approach for the intravenous delivery of leuprolide using core-cross-linked polymeric micelles.

Hu Q, van Gaal EV, Brundel P, Ippel H, Hackeng T, Rijcken CJ, Storm G, Hennink WE, Prakash J.

J Control Release. 2015 May 10;205:98-108. doi: 10.1016/j.jconrel.2014.12.023. Epub 2015 Jan 10.

PMID:
25583642
6.

Poly[N-(2-aminoethyl)ethyleneimine] as a new non-viral gene delivery carrier: the effect of two protonatable nitrogens in the monomer unit on gene delivery efficiency.

Khazaie Y, Dorkoosh FA, Novo L, Gaal EV, Fassihi A, Mirahmadi-Zareh SZ, Esfahani MH, Van Nostrum CF, Hennink WE.

J Pharm Pharm Sci. 2014;17(4):461-74.

7.

Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7.

Foroud T, Lai D, Koller D, Van't Hof F, Kurki MI, Anderson CS, Brown RD Jr, Connolly ES, Eriksson JG, Flaherty M, Fornage M, von Und Zu Fraunberg M, Gaál EI, Laakso A, Hernesniemi J, Huston J, Jääskeläinen JE, Kiemeney LA, Kivisaari R, Kleindorfer D, Ko N, Lehto H, Mackey J, Meissner I, Moomaw CJ, Mosley TH, Moskala M, Niemelä M, Palotie A, Pera J, Rinkel G, Ripke S, Rouleau G, Ruigrok Y, Sauerbeck L, Słowik A, Vermeulen SH, Woo D, Worrall BB, Broderick J; Familial Intracranial Aneurysm Study Investigators.

Stroke. 2014 Nov;45(11):3194-9. doi: 10.1161/STROKEAHA.114.006096. Epub 2014 Sep 25.

8.

Genetic risk load according to the site of intracranial aneurysms.

van 't Hof FN, Kurki MI, Kleinloog R, de Bakker PI, von und zu Fraunberg M, Jääskeläinen JE, Gaál EI, Lehto H, Kivisaari R, Laakso A, Niemelä M, Hernesniemi J, Brouwer MC, van de Beek D, Rinkel GJ, Ruigrok YM.

Neurology. 2014 Jul 1;83(1):34-9. doi: 10.1212/WNL.0000000000000547. Epub 2014 May 30.

PMID:
24879094
9.

High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms.

Kurki MI, Gaál EI, Kettunen J, Lappalainen T, Menelaou A, Anttila V, van 't Hof FN, von Und Zu Fraunberg M, Helisalmi S, Hiltunen M, Lehto H, Laakso A, Kivisaari R, Koivisto T, Ronkainen A, Rinne J, Kiemeney LA, Vermeulen SH, Kaunisto MA, Eriksson JG, Aromaa A, Perola M, Lehtimäki T, Raitakari OT, Salomaa V, Gunel M, Dermitzakis ET, Ruigrok YM, Rinkel GJ, Niemelä M, Hernesniemi J, Ripatti S, de Bakker PI, Palotie A, Jääskeläinen JE.

PLoS Genet. 2014 Jan 30;10(1):e1004134. doi: 10.1371/journal.pgen.1004134. eCollection 2014 Jan.

10.

Ligand-targeted particulate nanomedicines undergoing clinical evaluation: current status.

van der Meel R, Vehmeijer LJ, Kok RJ, Storm G, van Gaal EV.

Adv Drug Deliv Rev. 2013 Oct;65(10):1284-98. doi: 10.1016/j.addr.2013.08.012. Epub 2013 Sep 6. Review.

PMID:
24018362
11.

Comparison of vascular growth factors in the murine brain reveals placenta growth factor as prime candidate for CNS revascularization.

Gaál EI, Tammela T, Anisimov A, Marbacher S, Honkanen P, Zarkada G, Leppänen VM, Tatlisumak T, Hernesniemi J, Niemelä M, Alitalo K.

Blood. 2013 Aug 1;122(5):658-65. doi: 10.1182/blood-2012-07-441527. Epub 2013 Jun 26.

12.

Decationized crosslinked polyplexes for redox-triggered gene delivery.

Novo L, van Gaal EV, Mastrobattista E, van Nostrum CF, Hennink WE.

J Control Release. 2013 Aug 10;169(3):246-56. doi: 10.1016/j.jconrel.2013.03.035. Epub 2013 Apr 11.

PMID:
23583705
13.

Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis.

Anisimov A, Tvorogov D, Alitalo A, Leppänen VM, An Y, Han EC, Orsenigo F, Gaál EI, Holopainen T, Koh YJ, Tammela T, Korpisalo P, Keskitalo S, Jeltsch M, Ylä-Herttuala S, Dejana E, Koh GY, Choi C, Saharinen P, Alitalo K.

Circulation. 2013 Jan 29;127(4):424-34. doi: 10.1161/CIRCULATIONAHA.112.127472.

14.

Constrained and UV-activatable cell-penetrating peptides for intracellular delivery of liposomes.

Hansen MB, van Gaal E, Minten I, Storm G, van Hest JC, Löwik DW.

J Control Release. 2012 Nov 28;164(1):87-94. doi: 10.1016/j.jconrel.2012.10.008. Epub 2012 Oct 17.

PMID:
23085152
15.

Mortality after surgery in Europe: a 7 day cohort study.

Pearse RM, Moreno RP, Bauer P, Pelosi P, Metnitz P, Spies C, Vallet B, Vincent JL, Hoeft A, Rhodes A; European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology.

Lancet. 2012 Sep 22;380(9847):1059-65. doi: 10.1016/S0140-6736(12)61148-9.

16.

Intracranial aneurysm risk locus 5q23.2 is associated with elevated systolic blood pressure.

Gaál EI, Salo P, Kristiansson K, Rehnström K, Kettunen J, Sarin AP, Niemelä M, Jula A, Raitakari OT, Lehtimäki T, Eriksson JG, Widen E, Günel M, Kurki M, von und Zu Fraunberg M, Jääskeläinen JE, Hernesniemi J, Järvelin MR, Pouta A; International Consortium for Blood Pressure Genome-Wide Association Studies, Newton-Cheh C, Salomaa V, Palotie A, Perola M.

PLoS Genet. 2012;8(3):e1002563. doi: 10.1371/journal.pgen.1002563. Epub 2012 Mar 15.

17.

Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk.

Yasuno K, Bakırcıoğlu M, Low SK, Bilgüvar K, Gaál E, Ruigrok YM, Niemelä M, Hata A, Bijlenga P, Kasuya H, Jääskeläinen JE, Krex D, Auburger G, Simon M, Krischek B, Ozturk AK, Mane S, Rinkel GJ, Steinmetz H, Hernesniemi J, Schaller K, Zembutsu H, Inoue I, Palotie A, Cambien F, Nakamura Y, Lifton RP, Günel M.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19707-12. doi: 10.1073/pnas.1117137108. Epub 2011 Nov 21.

18.

Quantitative and qualitative flow cytometric analysis of nanosized cell-derived membrane vesicles.

Nolte-'t Hoen EN, van der Vlist EJ, Aalberts M, Mertens HC, Bosch BJ, Bartelink W, Mastrobattista E, van Gaal EV, Stoorvogel W, Arkesteijn GJ, Wauben MH.

Nanomedicine. 2012 Jul;8(5):712-20. doi: 10.1016/j.nano.2011.09.006. Epub 2011 Oct 22.

PMID:
22024193
19.

A step-by-step approach to study the influence of N-acetylation on the adjuvanticity of N,N,N-trimethyl chitosan (TMC) in an intranasal nanoparticulate influenza virus vaccine.

Verheul RJ, Hagenaars N, van Es T, van Gaal EV, de Jong PH, Bruijns S, Mastrobattista E, Slütter B, Que I, Heldens JG, van den Bosch H, Glansbeek HL, Hennink WE, Jiskoot W.

Eur J Pharm Sci. 2012 Mar 12;45(4):467-74. doi: 10.1016/j.ejps.2011.10.001. Epub 2011 Oct 8.

PMID:
22009112
20.

How to screen non-viral gene delivery systems in vitro?

van Gaal EV, van Eijk R, Oosting RS, Kok RJ, Hennink WE, Crommelin DJ, Mastrobattista E.

J Control Release. 2011 Sep 25;154(3):218-32. doi: 10.1016/j.jconrel.2011.05.001. Epub 2011 May 7. Review.

PMID:
21600249

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