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Items: 1 to 20 of 71


Analysis of microRNA and Gene Expression Profiles in Multiple Sclerosis: Integrating Interaction Data to Uncover Regulatory Mechanisms.

Freiesleben S, Hecker M, Zettl UK, Fuellen G, Taher L.

Sci Rep. 2016 Oct 3;6:34512. doi: 10.1038/srep34512.


Polymorphisms of the murine mitochondrial ND4, CYTB and COX3 genes impact hematopoiesis during aging.

Kretzschmar C, Roolf C, Timmer K, Sekora A, Knübel G, Escobar HM, Fuellen G, Ibrahim SM, Tiedge M, Baltrusch S, Jaster R, Köhling R, Junghanss C.

Oncotarget. 2016 Sep 10. doi: 10.18632/oncotarget.11952. [Epub ahead of print]


Uncoupling protein 2 deficiency results in higher neutrophil counts and lower B-cell counts during aging in mice.

Kretzschmar C, Roolf C, Timmer K, Sekora A, Knübel G, Escobar HM, Jaster R, Müller S, Fuellen G, Köhling R, Junghanss C.

Exp Hematol. 2016 Aug 17. pii: S0301-472X(16)30562-8. doi: 10.1016/j.exphem.2016.08.003.


Revealing complex function, process and pathway interactions with high-throughput expression and biological annotation data.

Singh NK, Ernst M, Liebscher V, Fuellen G, Taher L.

Mol Biosyst. 2016 Oct 20;12(10):3196-208. doi: 10.1039/c6mb00280c. Epub 2016 Aug 10.


Proteomic Analysis of Mouse Oocytes Identifies PRMT7 as a Reprogramming Factor that Replaces SOX2 in the Induction of Pluripotent Stem Cells.

Wang B, Pfeiffer MJ, Drexler HC, Fuellen G, Boiani M.

J Proteome Res. 2016 Aug 5;15(8):2407-21. doi: 10.1021/acs.jproteome.5b01083. Epub 2016 Jul 12.


Ageing with elegans: a research proposal to map healthspan pathways.

Luyten W, Antal P, Braeckman BP, Bundy J, Cirulli F, Fang-Yen C, Fuellen G, Leroi A, Liu Q, Martorell P, Metspalu A, Perola M, Ristow M, Saul N, Schoofs L, Siems K, Temmerman L, Smets T, Wolk A, Rattan SI.

Biogerontology. 2016 Aug;17(4):771-82. doi: 10.1007/s10522-016-9644-x. Epub 2016 Apr 4.


Advanced Running Performance by Genetic Predisposition in Male Dummerstorf Marathon Mice (DUhTP) Reveals Higher Sterol Regulatory Element-Binding Protein (SREBP) Related mRNA Expression in the Liver and Higher Serum Levels of Progesterone.

Ohde D, Moeller M, Brenmoehl J, Walz C, Ponsuksili S, Schwerin M, Fuellen G, Hoeflich A.

PLoS One. 2016 Jan 22;11(1):e0146748. doi: 10.1371/journal.pone.0146748. eCollection 2016.


Living Long and Well: Prospects for a Personalized Approach to the Medicine of Ageing.

Fuellen G, Schofield P, Flatt T, Schulz RJ, Boege F, Kraft K, Rimbach G, Ibrahim S, Tietz A, Schmidt C, Köhling R, Simm A.

Gerontology. 2016;62(4):409-16. doi: 10.1159/000442746. Epub 2015 Dec 17.


TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability.

Bahnassawy L, Perumal TM, Gonzalez-Cano L, Hillje AL, Taher L, Makalowski W, Suzuki Y, Fuellen G, del Sol A, Schwamborn JC.

Sci Rep. 2015 Aug 26;5:13456. doi: 10.1038/srep13456.


Reduced adolescent-age spatial learning ability associated with elevated juvenile-age superoxide levels in complex I mouse mutants.

Mayer J, Reichart G, Tokay T, Lange F, Baltrusch S, Junghanss C, Wolkenhauer O, Jaster R, Kunz M, Tiedge M, Ibrahim S, Fuellen G, Köhling R.

PLoS One. 2015 Apr 8;10(4):e0123863. doi: 10.1371/journal.pone.0123863. eCollection 2015.


A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging.

Schauer M, Kottek T, Schönherr M, Bhattacharya A, Ibrahim SM, Hirose M, Köhling R, Fuellen G, Schmitz U, Kunz M.

Oncotarget. 2015 Apr 20;6(11):8552-66.


Comparative computational analysis of pluripotency in human and mouse stem cells.

Ernst M, Abu Dawud R, Kurtz A, Schotta G, Taher L, Fuellen G.

Sci Rep. 2015 Jan 21;5:7927. doi: 10.1038/srep07927.


Differences in embryo quality are associated with differences in oocyte composition: a proteomic study in inbred mice.

Pfeiffer MJ, Taher L, Drexler H, Suzuki Y, Makałowski W, Schwarzer C, Wang B, Fuellen G, Boiani M.

Proteomics. 2015 Feb;15(4):675-87. doi: 10.1002/pmic.201400334. Epub 2015 Jan 3.


Systems biology approaches in aging research.

Chauhan A, Liebal UW, Vera J, Baltrusch S, Junghanß C, Tiedge M, Fuellen G, Wolkenhauer O, Köhling R.

Interdiscip Top Gerontol. 2015;40:155-76. doi: 10.1159/000364981. Epub 2014 Oct 14. Review.


Bioinformatics approaches to single-blastomere transcriptomics.

Taher L, Pfeiffer MJ, Fuellen G.

Mol Hum Reprod. 2015 Feb;21(2):115-25. doi: 10.1093/molehr/gau083. Epub 2014 Sep 19.


Adenoviral overexpression of Lhx2 attenuates cell viability but does not preserve the stem cell like phenotype of hepatic stellate cells.

Genz B, Thomas M, Pützer BM, Siatkowski M, Fuellen G, Vollmar B, Abshagen K.

Exp Cell Res. 2014 Nov 1;328(2):429-43. doi: 10.1016/j.yexcr.2014.06.019. Epub 2014 Jul 1.


Inbred mouse strains reveal biomarkers that are pro-longevity, antilongevity or role switching.

Moeller M, Hirose M, Mueller S, Roolf C, Baltrusch S, Ibrahim S, Junghanss C, Wolkenhauer O, Jaster R, Köhling R, Kunz M, Tiedge M, Schofield PN, Fuellen G.

Aging Cell. 2014 Aug;13(4):729-38. doi: 10.1111/acel.12226. Epub 2014 May 23.


Age-dependent effects of UCP2 deficiency on experimental acute pancreatitis in mice.

Müller S, Kaiser H, Krüger B, Fitzner B, Lange F, Bock CN, Nizze H, Ibrahim SM, Fuellen G, Wolkenhauer O, Jaster R.

PLoS One. 2014 Apr 10;9(4):e94494. doi: 10.1371/journal.pone.0094494. eCollection 2014.


Maternal age effect on mouse oocytes: new biological insight from proteomic analysis.

Schwarzer C, Siatkowski M, Pfeiffer MJ, Baeumer N, Drexler HC, Wang B, Fuellen G, Boiani M.

Reproduction. 2014 Jul;148(1):55-72. doi: 10.1530/REP-14-0126. Epub 2014 Mar 31.


Aberrant expressions of delta-protocadherins in the brain of Npc1 mutant mice.

Yan X, Lukas J, Lin J, Ernst M, Koczan D, Witt M, Fuellen G, Wree A, Rolfs A, Luo J.

Histol Histopathol. 2014 Sep;29(9):1185-99. Epub 2014 Mar 26.

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