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Items: 1 to 20 of 125

1.

Cigarette Smoke Toxins-induced mitochondrial dysfunction and pancreatitis involves Aryl hydrocarbon receptor mediated Cyp1 gene expression: protective effects of resveratrol.

Ghosh J, Roy Chowdhury A, Srinivasan S, Chattopadhyay M, Bose M, Bhattacharya S, Raza H, Fuchs SY, Rustgi AK, Gonzalez FJ, Avadhani NG.

Toxicol Sci. 2018 Aug 25. doi: 10.1093/toxsci/kfy206. [Epub ahead of print]

PMID:
30165701
2.

A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival.

Bu Y, Yoshida A, Chitnis N, Altman BJ, Tameire F, Oran A, Gennaro V, Armeson KE, McMahon SB, Wertheim GB, Dang CV, Ruggero D, Koumenis C, Fuchs SY, Diehl JA.

Nat Cell Biol. 2018 Jan;20(1):104-115. doi: 10.1038/s41556-017-0006-y. Epub 2017 Dec 11.

3.

Downregulation of the IFNAR1 chain of type 1 interferon receptor contributes to the maintenance of the haematopoietic stem cells.

Gui J, Zhao B, Lyu K, Tong W, Fuchs SY.

Cancer Biol Ther. 2017 Jul 3;18(7):534-543. doi: 10.1080/15384047.2017.1345395. Epub 2017 Jul 5.

4.

Expression of the IFNAR1 chain of type 1 interferon receptor in benign cells protects against progression of acute leukemia.

Zhao B, Bhattacharya S, Yu Q, Fuchs SY.

Leuk Lymphoma. 2018 Jan;59(1):171-177. doi: 10.1080/10428194.2017.1319053. Epub 2017 May 15.

PMID:
28503979
5.

Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment.

Katlinski KV, Gui J, Katlinskaya YV, Ortiz A, Chakraborty R, Bhattacharya S, Carbone CJ, Beiting DP, Girondo MA, Peck AR, Puré E, Chatterji P, Rustgi AK, Diehl JA, Koumenis C, Rui H, Fuchs SY.

Cancer Cell. 2017 Feb 13;31(2):194-207. doi: 10.1016/j.ccell.2017.01.004.

6.

PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma.

Pytel D, Gao Y, Mackiewicz K, Katlinskaya YV, Staschke KA, Paredes MC, Yoshida A, Qie S, Zhang G, Chajewski OS, Wu L, Majsterek I, Herlyn M, Fuchs SY, Diehl JA.

PLoS Genet. 2016 Dec 15;12(12):e1006518. doi: 10.1371/journal.pgen.1006518. eCollection 2016 Dec.

7.

A Potent In Vivo Antitumor Efficacy of Novel Recombinant Type I Interferon.

Zhang KJ, Yin XF, Yang YQ, Li HL, Xu YN, Chen LY, Liu XJ, Yuan SJ, Fang XL, Xiao J, Wu S, Xu HN, Chu L, Katlinski KV, Katlinskaya YV, Guo RB, Wei GW, Wang DC, Liu XY, Fuchs SY.

Clin Cancer Res. 2017 Apr 15;23(8):2038-2049. doi: 10.1158/1078-0432.CCR-16-1386. Epub 2016 Sep 28.

8.

Therapeutic Elimination of the Type 1 Interferon Receptor for Treating Psoriatic Skin Inflammation.

Gui J, Gober M, Yang X, Katlinski KV, Marshall CM, Sharma M, Werth VP, Baker DP, Rui H, Seykora JT, Fuchs SY.

J Invest Dermatol. 2016 Oct;136(10):1990-2002. doi: 10.1016/j.jid.2016.06.608. Epub 2016 Jun 29.

9.

Mitochondrial stress-induced p53 attenuates HIF-1α activity by physical association and enhanced ubiquitination.

Chowdhury AR, Long A, Fuchs SY, Rustgi A, Avadhani NG.

Oncogene. 2017 Jan 19;36(3):397-409. doi: 10.1038/onc.2016.211. Epub 2016 Jun 27.

10.

miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis.

Xu Z, Bu Y, Chitnis N, Koumenis C, Fuchs SY, Diehl JA.

Nat Commun. 2016 May 13;7:11422. doi: 10.1038/ncomms11422.

11.

Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression.

Katlinskaya YV, Katlinski KV, Yu Q, Ortiz A, Beiting DP, Brice A, Davar D, Sanders C, Kirkwood JM, Rui H, Xu X, Koumenis C, Diehl JA, Fuchs SY.

Cell Rep. 2016 Apr 5;15(1):171-180. doi: 10.1016/j.celrep.2016.03.006. Epub 2016 Mar 24.

12.

BRAF Inhibitors and IFNα: Plus, Minus, or Indeterminate?

Davar D, Fuchs SY, Kirkwood JM.

J Natl Cancer Inst. 2016 Feb 5;108(7). pii: djv432. doi: 10.1093/jnci/djv432. Print 2016 Jul. No abstract available.

PMID:
26851801
13.

Anti-metastatic functions of type 1 interferons: Foundation for the adjuvant therapy of cancer.

Ortiz A, Fuchs SY.

Cytokine. 2017 Jan;89:4-11. doi: 10.1016/j.cyto.2016.01.010. Epub 2016 Jan 25. Review.

14.

Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.

Katlinskaya YV, Katlinski KV, Lasri A, Li N, Beiting DP, Durham AC, Yang T, Pikarsky E, Lengner CJ, Johnson FB, Ben-Neriah Y, Fuchs SY.

Mol Cell Biol. 2016 Jan 25;36(7):1124-35. doi: 10.1128/MCB.00988-15.

15.

Hemagglutinin of Influenza A Virus Antagonizes Type I Interferon (IFN) Responses by Inducing Degradation of Type I IFN Receptor 1.

Xia C, Vijayan M, Pritzl CJ, Fuchs SY, McDermott AB, Hahm B.

J Virol. 2015 Dec 16;90(5):2403-17. doi: 10.1128/JVI.02749-15.

16.

Type I interferons mediate pancreatic toxicities of PERK inhibition.

Yu Q, Zhao B, Gui J, Katlinski KV, Brice A, Gao Y, Li C, Kushner JA, Koumenis C, Diehl JA, Fuchs SY.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15420-5. doi: 10.1073/pnas.1516362112. Epub 2015 Dec 1.

17.

Type 1 interferons contribute to the clearance of senescent cell.

Katlinskaya YV, Carbone CJ, Yu Q, Fuchs SY.

Cancer Biol Ther. 2015;16(8):1214-9. doi: 10.1080/15384047.2015.1056419. Epub 2015 Jun 5.

18.

ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis.

Dey S, Sayers CM, Verginadis II, Lehman SL, Cheng Y, Cerniglia GJ, Tuttle SW, Feldman MD, Zhang PJ, Fuchs SY, Diehl JA, Koumenis C.

J Clin Invest. 2015 Jul 1;125(7):2592-608. doi: 10.1172/JCI78031. Epub 2015 May 26.

19.

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

Yu Q, Katlinskaya YV, Carbone CJ, Zhao B, Katlinski KV, Zheng H, Guha M, Li N, Chen Q, Yang T, Lengner CJ, Greenberg RA, Johnson FB, Fuchs SY.

Cell Rep. 2015 May 5;11(5):785-797. doi: 10.1016/j.celrep.2015.03.069. Epub 2015 Apr 23.

20.

Type I interferon controls propagation of long interspersed element-1.

Yu Q, Carbone CJ, Katlinskaya YV, Zheng H, Zheng K, Luo M, Wang PJ, Greenberg RA, Fuchs SY.

J Biol Chem. 2015 Apr 17;290(16):10191-9. doi: 10.1074/jbc.M114.612374. Epub 2015 Feb 25.

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