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Items: 1 to 20 of 204

1.

Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation.

Zaghlool SB, Mook-Kanamori DO, Kader S, Stephan N, Halama A, Engelke R, Sarwath H, Al-Dous EK, Mohamoud YA, Roemisch-Margl W, Adamski J, Kastenmüller G, Friedrich N, Visconti A, Tsai PC, Spector T, Bell J, Falchi M, Wahl A, Waldenberger M, Peters A, Gieger C, Pezer M, Lauc G, Graumann J, Malek JA, Suhre K.

Hum Mol Genet. 2018 Jan 8. doi: 10.1093/hmg/ddy006. [Epub ahead of print]

PMID:
29325019
2.

Association of sex hormones with physical, laboratory, and imaging markers of anthropometry in men and women from the general population.

Seyfart T, Friedrich N, Kische H, Bülow R, Wallaschofski H, Völzke H, Nauck M, Keevil BG, Haring R.

PLoS One. 2018 Jan 11;13(1):e0189042. doi: 10.1371/journal.pone.0189042. eCollection 2018.

3.

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies.

van der Lee SJ, Teunissen CE, Pool R, Shipley MJ, Teumer A, Chouraki V, Melo van Lent D, Tynkkynen J, Fischer K, Hernesniemi J, Metspalu A, Singh-Manoux A, Verhoeven A, Willemsen G, de Leeuw FA, Wagner H, van Dongen J, Hertel J, Budde K, Willems van Dijk K, Weinhold L, Ikram MA, Pietzner M, Perola M, Wagner M, Friedrich N, Slagboom PE, Scheltens P, Yang Q, Gertzen RE, Egert S, Li S, Hankemeier T, van Beijsterveldt CEM, Ramachandran V, Maier W, Peeters CFW, Jörgen Grabe H, Ramirez A, Seshadri S, Haller T, Kivimäki M, Salomaa V, Demirkan A, Boomsma D, van der Flier WM, Amin N, van Duijn CM.

Alzheimers Dement. 2018 Jan 6. pii: S1552-5260(17)33855-4. doi: 10.1016/j.jalz.2017.11.012. [Epub ahead of print]

PMID:
29316447
4.

Hit Dexter: A Machine-learning Model for the Prediction of Frequent Hitters.

Stork C, Wagner J, Friedrich NO, de Bruyn Kops C, Šícho M, Kirchmair J.

ChemMedChem. 2017 Dec 29. doi: 10.1002/cmdc.201700673. [Epub ahead of print]

PMID:
29285887
5.

Development of a high-throughput bead based assay system to measure HIV-1 specific immune signatures in clinical samples.

Liechti T, Kadelka C, Ebner H, Friedrich N, Kouyos RD, Günthard HF, Trkola A.

J Immunol Methods. 2017 Dec 22. pii: S0022-1759(17)30423-4. doi: 10.1016/j.jim.2017.12.003. [Epub ahead of print]

6.

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T, Feitosa MF, Masca NGD, Manning AK, Medina-Gomez C, Mudgal P, Ng MCY, Reiner AP, Vedantam S, Willems SM, Winkler TW, Abecasis G, Aben KK, Alam DS, Alharthi SE, Allison M, Amouyel P, Asselbergs FW, Auer PL, Balkau B, Bang LE, Barroso I, Bastarache L, Benn M, Bergmann S, Bielak LF, Blüher M, Boehnke M, Boeing H, Boerwinkle E, Böger CA, Bork-Jensen J, Bots ML, Bottinger EP, Bowden DW, Brandslund I, Breen G, Brilliant MH, Broer L, Brumat M, Burt AA, Butterworth AS, Campbell PT, Cappellani S, Carey DJ, Catamo E, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Cocca M, Collins FS, Cook JP, Corley J, Corominas Galbany J, Cox AJ, Crosslin DS, Cuellar-Partida G, D'Eustacchio A, Danesh J, Davies G, Bakker PIW, Groot MCH, Mutsert R, Deary IJ, Dedoussis G, Demerath EW, Heijer M, Hollander AI, Ruijter HM, Dennis JG, Denny JC, Angelantonio E, Drenos F, Du M, Dubé MP, Dunning AM, Easton DF, Edwards TL, Ellinghaus D, Ellinor PT, Elliott P, Evangelou E, Farmaki AE, Farooqi IS, Faul JD, Fauser S, Feng S, Ferrannini E, Ferrieres J, Florez JC, Ford I, Fornage M, Franco OH, Franke A, Franks PW, Friedrich N, Frikke-Schmidt R, Galesloot TE, Gan W, Gandin I, Gasparini P, Gibson J, Giedraitis V, Gjesing AP, Gordon-Larsen P, Gorski M, Grabe HJ, Grant SFA, Grarup N, Griffiths HL, Grove ML, Gudnason V, Gustafsson S, Haessler J, Hakonarson H, Hammerschlag AR, Hansen T, Harris KM, Harris TB, Hattersley AT, Have CT, Hayward C, He L, Heard-Costa NL, Heath AC, Heid IM, Helgeland Ø, Hernesniemi J, Hewitt AW, Holmen OL, Hovingh GK, Howson JMM, Hu Y, Huang PL, Huffman JE, Ikram MA, Ingelsson E, Jackson AU, Jansson JH, Jarvik GP, Jensen GB, Jia Y, Johansson S, Jørgensen ME, Jørgensen T, Jukema JW, Kahali B, Kahn RS, Kähönen M, Kamstrup PR, Kanoni S, Kaprio J, Karaleftheri M, Kardia SLR, Karpe F, Kathiresan S, Kee F, Kiemeney LA, Kim E, Kitajima H, Komulainen P, Kooner JS, Kooperberg C, Korhonen T, Kovacs P, Kuivaniemi H, Kutalik Z, Kuulasmaa K, Kuusisto J, Laakso M, Lakka TA, Lamparter D, Lange EM, Lange LA, Langenberg C, Larson EB, Lee NR, Lehtimäki T, Lewis CE, Li H, Li J, Li-Gao R, Lin H, Lin KH, Lin LA, Lin X, Lind L, Lindström J, Linneberg A, Liu CT, Liu DJ, Liu Y, Lo KS, Lophatananon A, Lotery AJ, Loukola A, Luan J, Lubitz SA, Lyytikäinen LP, Männistö S, Marenne G, Mazul AL, McCarthy MI, McKean-Cowdin R, Medland SE, Meidtner K, Milani L, Mistry V, Mitchell P, Mohlke KL, Moilanen L, Moitry M, Montgomery GW, Mook-Kanamori DO, Moore C, Mori TA, Morris AD, Morris AP, Müller-Nurasyid M, Munroe PB, Nalls MA, Narisu N, Nelson CP, Neville M, Nielsen SF, Nikus K, Njølstad PR, Nordestgaard BG, Nyholt DR, O'Connel JR, O'Donoghue ML, Olde Loohuis LM, Ophoff RA, Owen KR, Packard CJ, Padmanabhan S, Palmer CNA, Palmer ND, Pasterkamp G, Patel AP, Pattie A, Pedersen O, Peissig PL, Peloso GM, Pennell CE, Perola M, Perry JA, Perry JRB, Pers TH, Person TN, Peters A, Petersen ERB, Peyser PA, Pirie A, Polasek O, Polderman TJ, Puolijoki H, Raitakari OT, Rasheed A, Rauramaa R, Reilly DF, Renström F, Rheinberger M, Ridker PM, Rioux JD, Rivas MA, Roberts DJ, Robertson NR, Robino A, Rolandsson O, Rudan I, Ruth KS, Saleheen D, Salomaa V, Samani NJ, Sapkota Y, Sattar N, Schoen RE, Schreiner PJ, Schulze MB, Scott RA, Segura-Lepe MP, Shah SH, Sheu WH, Sim X, Slater AJ, Small KS, Smith AV, Southam L, Spector TD, Speliotes EK, Starr JM, Stefansson K, Steinthorsdottir V, Stirrups KE, Strauch K, Stringham HM, Stumvoll M, Sun L, Surendran P, Swift AJ, Tada H, Tansey KE, Tardif JC, Taylor KD, Teumer A, Thompson DJ, Thorleifsson G, Thorsteinsdottir U, Thuesen BH, Tönjes A, Tromp G, Trompet S, Tsafantakis E, Tuomilehto J, Tybjaerg-Hansen A, Tyrer JP, Uher R, Uitterlinden AG, Uusitupa M, Laan SW, Duijn CM, Leeuwen N, van Setten J, Vanhala M, Varbo A, Varga TV, Varma R, Velez Edwards DR, Vermeulen SH, Veronesi G, Vestergaard H, Vitart V, Vogt TF, Völker U, Vuckovic D, Wagenknecht LE, Walker M, Wallentin L, Wang F, Wang CA, Wang S, Wang Y, Ware EB, Wareham NJ, Warren HR, Waterworth DM, Wessel J, White HD, Willer CJ, Wilson JG, Witte DR, Wood AR, Wu Y, Yaghootkar H, Yao J, Yao P, Yerges-Armstrong LM, Young R, Zeggini E, Zhan X, Zhang W, Zhao JH, Zhao W, Zhou W, Zondervan KT; CHD Exome+ Consortium; EPIC-CVD Consortium; ExomeBP Consortium; Global Lipids Genetic Consortium; GoT2D Genes Consortium; EPIC InterAct Consortium; INTERVAL Study; ReproGen Consortium; T2D-Genes Consortium; MAGIC Investigators; Understanding Society Scientific Group, Rotter JI, Pospisilik JA, Rivadeneira F, Borecki IB, Deloukas P, Frayling TM, Lettre G, North KE, Lindgren CM, Hirschhorn JN, Loos RJF.

Nat Genet. 2018 Jan;50(1):26-41. doi: 10.1038/s41588-017-0011-x. Epub 2017 Dec 22.

PMID:
29273807
7.

Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis.

Skaaby T, Taylor AE, Jacobsen RK, Møllehave LT, Friedrich N, Thuesen BH, Shabanzadeh DM, Paternoster L, Völker U, Nauck M, Völzke H, Munafò M, Hansen T, Pedersen O, Jørgensen T, Grarup N, Linneberg A.

Eur J Clin Nutr. 2017 Dec 18. doi: 10.1038/s41430-017-0037-2. [Epub ahead of print]

PMID:
29249824
8.

Association between serum neuron-specific enolase, age, overweight, and structural MRI patterns in 901 subjects.

Hoffmann J, Janowitz D, Van der Auwera S, Wittfeld K, Nauck M, Friedrich N, Habes M, Davatzikos C, Terock J, Bahls M, Goltz A, Kuhla A, Völzke H, Jörgen Grabe H.

Transl Psychiatry. 2017 Dec 8;7(12):1272. doi: 10.1038/s41398-017-0035-0.

PMID:
29217819
9.

Metabomatching: Using genetic association to identify metabolites in proton NMR spectroscopy.

Rueedi R, Mallol R, Raffler J, Lamparter D, Friedrich N, Vollenweider P, Waeber G, Kastenmüller G, Kutalik Z, Bergmann S.

PLoS Comput Biol. 2017 Dec 1;13(12):e1005839. doi: 10.1371/journal.pcbi.1005839. eCollection 2017 Dec.

10.

Comprehensive metabolic profiling of chronic low-grade inflammation among generally healthy individuals.

Pietzner M, Kaul A, Henning AK, Kastenmüller G, Artati A, Lerch MM, Adamski J, Nauck M, Friedrich N.

BMC Med. 2017 Nov 30;15(1):210. doi: 10.1186/s12916-017-0974-6.

11.

Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives.

Hertel J, König J, Homuth G, Van der Auwera S, Wittfeld K, Pietzner M, Kacprowski T, Pfeiffer L, Kretschmer A, Waldenberger M, Kastenmüller G, Artati A, Suhre K, Adamski J, Langner S, Völker U, Völzke H, Nauck M, Friedrich N, Grabe HJ.

Sci Rep. 2017 Oct 26;7(1):14111. doi: 10.1038/s41598-017-13927-7.

12.

Benchmarking Commercial Conformer Ensemble Generators.

Friedrich NO, de Bruyn Kops C, Flachsenberg F, Sommer K, Rarey M, Kirchmair J.

J Chem Inf Model. 2017 Nov 27;57(11):2719-2728. doi: 10.1021/acs.jcim.7b00505. Epub 2017 Oct 18.

PMID:
28967749
13.

Phenotype-driven identification of modules in a hierarchical map of multifluid metabolic correlations.

Do KT, Pietzner M, Rasp DJ, Friedrich N, Nauck M, Kocher T, Suhre K, Mook-Kanamori DO, Kastenmüller G, Krumsiek J.

NPJ Syst Biol Appl. 2017 Sep 21;3:28. doi: 10.1038/s41540-017-0029-9. eCollection 2017.

14.

Abdominal fat deposits determined by magnetic resonance imaging in relation to leptin and vaspin levels as well as insulin resistance in the general adult population.

Genske F, Kühn JP, Pietzner M, Homuth G, Rathmann W, Grabe HJ, Völzke H, Wallaschofski H, Friedrich N.

Int J Obes (Lond). 2017 Aug 14. doi: 10.1038/ijo.2017.187. [Epub ahead of print]

PMID:
28925406
15.

Comprehensive metabolic characterization of serum osteocalcin action in a large non-diabetic sample.

Entenmann L, Pietzner M, Artati A, Hannemann A, Henning AK, Kastenmüller G, Völzke H, Nauck M, Adamski J, Wallaschofski H, Friedrich N.

PLoS One. 2017 Sep 18;12(9):e0184721. doi: 10.1371/journal.pone.0184721. eCollection 2017.

16.

Sex hormones and quantitative ultrasound parameters at the heel in men and women from the general population.

Pätzug K, Friedrich N, Kische H, Hannemann A, Völzke H, Nauck M, Keevil BG, Haring R.

Bone Rep. 2017 Aug 18;7:51-56. doi: 10.1016/j.bonr.2017.08.003. eCollection 2017 Dec.

17.

Serum chemerin levels are inversely associated with renal function in a general population.

Zylla S, Rettig R, Völzke H, Endlich K, Nauck M, Friedrich N.

Clin Endocrinol (Oxf). 2018 Jan;88(1):146-153. doi: 10.1111/cen.13449. Epub 2017 Sep 13.

PMID:
28833355
18.

Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization.

Skaaby T, Taylor AE, Thuesen BH, Jacobsen RK, Friedrich N, Møllehave LT, Hansen S, Larsen SC, Völker U, Nauck M, Völzke H, Hansen T, Pedersen O, Jørgensen T, Paternoster L, Munafò M, Grarup N, Linneberg A.

Allergy. 2018 Jan;73(1):153-164. doi: 10.1111/all.13242. Epub 2017 Aug 2.

PMID:
28675761
19.

Identification of urine metabolites associated with 5-year changes in biomarkers of glucose homoeostasis.

Friedrich N, Skaaby T, Pietzner M, Budde K, Thuesen BH, Nauck M, Linneberg A.

Diabetes Metab. 2017 Jun 29. pii: S1262-3636(17)30105-2. doi: 10.1016/j.diabet.2017.05.007. [Epub ahead of print]

PMID:
28669514
20.

Mumps Virus SH Protein Inhibits NF-κB Activation by Interacting with Tumor Necrosis Factor Receptor 1, Interleukin-1 Receptor 1, and Toll-Like Receptor 3 Complexes.

Franz S, Rennert P, Woznik M, Grützke J, Lüdde A, Arriero Pais EM, Finsterbusch T, Geyer H, Mankertz A, Friedrich N.

J Virol. 2017 Aug 24;91(18). pii: e01037-17. doi: 10.1128/JVI.01037-17. Print 2017 Sep 15.

PMID:
28659487

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