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Items: 18

1.

Physicochemical and Pharmacokinetic Profiles of Gadopiclenol: A New Macrocyclic Gadolinium Chelate With High T1 Relaxivity.

Robic C, Port M, Rousseaux O, Louguet S, Fretellier N, Catoen S, Factor C, Le Greneur S, Medina C, Bourrinet P, Raynal I, Idée JM, Corot C.

Invest Radiol. 2019 Aug;54(8):475-484. doi: 10.1097/RLI.0000000000000563.

PMID:
30973459
2.

Does Age Interfere With Gadolinium Toxicity and Presence in Brain and Bone Tissues?: A Comparative Gadoterate Versus Gadodiamide Study in Juvenile and Adult Rats.

Fretellier N, Granottier A, Rasschaert M, Grindel AL, Baudimont F, Robert P, Idée JM, Corot C.

Invest Radiol. 2019 Feb;54(2):61-71. doi: 10.1097/RLI.0000000000000517.

3.

Multimodal Imaging Study of Gadolinium Presence in Rat Cerebellum: Differences Between Gd Chelates, Presence in the Virchow-Robin Space, Association With Lipofuscin, and Hypotheses About Distribution Pathway.

Rasschaert M, Schroeder JA, Wu TD, Marco S, Emerit A, Siegmund H, Fischer C, Fretellier N, Idée JM, Corot C, Brochhausen C, Guerquin-Kern JL.

Invest Radiol. 2018 Sep;53(9):518-528. doi: 10.1097/RLI.0000000000000490.

4.

Methodological Aspects for Preclinical Evaluation of Gadolinium Presence in Brain Tissue: Critical Appraisal and Suggestions for Harmonization-A Joint Initiative.

Robert P, Frenzel T, Factor C, Jost G, Rasschaert M, Schuetz G, Fretellier N, Boyken J, Idée JM, Pietsch H.

Invest Radiol. 2018 Sep;53(9):499-517. doi: 10.1097/RLI.0000000000000467. Review.

5.

Region of Interest Selection in Nonclinical Studies of Accumulated Gadolinium-based Contrast Agent-induced T1 Hyperintensity in Deep Cerebellar Nuclei.

Idée JM, Robert P, Raynaud JS, Rasschaert M, Fretellier N, Factor C, Corot C.

Radiology. 2018 Apr;287(1):360-362. doi: 10.1148/radiol.2017171740. No abstract available.

PMID:
29558301
6.

Gadolinium Retention, Brain T1 Hyperintensity, and Endogenous Metals: A Comparative Study of Macrocyclic Versus Linear Gadolinium Chelates in Renally Sensitized Rats.

Rasschaert M, Emerit A, Fretellier N, Factor C, Robert P, Idée JM, Corot C.

Invest Radiol. 2018 Jun;53(6):328-337. doi: 10.1097/RLI.0000000000000447.

7.

Moderate Renal Failure Accentuates T1 Signal Enhancement in the Deep Cerebellar Nuclei of Gadodiamide-Treated Rats.

Rasschaert M, Idée JM, Robert P, Fretellier N, Vives V, Violas X, Ballet S, Corot C.

Invest Radiol. 2017 May;52(5):255-264. doi: 10.1097/RLI.0000000000000339.

8.

Total gadolinium tissue deposition and skin structural findings following the administration of structurally different gadolinium chelates in healthy and ovariectomized female rats.

Wáng YX, Schroeder J, Siegmund H, Idée JM, Fretellier N, Jestin-Mayer G, Factor C, Deng M, Kang W, Morcos SK.

Quant Imaging Med Surg. 2015 Aug;5(4):534-45. doi: 10.3978/j.issn.2223-4292.2015.05.03.

9.

Non-clinical safety assessment of gadoterate meglumine (Dotarem(®)) in neonatal and juvenile rats.

Giorgi H, Ammerman J, Briffaux JP, Fretellier N, Corot C, Bourrinet P.

Regul Toxicol Pharmacol. 2015 Dec;73(3):960-70. doi: 10.1016/j.yrtph.2015.09.018. Epub 2015 Sep 14.

PMID:
26382613
10.

T1-Weighted Hypersignal in the Deep Cerebellar Nuclei After Repeated Administrations of Gadolinium-Based Contrast Agents in Healthy Rats: Difference Between Linear and Macrocyclic Agents.

Robert P, Lehericy S, Grand S, Violas X, Fretellier N, Idée JM, Ballet S, Corot C.

Invest Radiol. 2015 Aug;50(8):473-80. doi: 10.1097/RLI.0000000000000181.

11.

Distribution profile of gadolinium in gadolinium chelate-treated renally-impaired rats: role of pharmaceutical formulation.

Fretellier N, Salhi M, Schroeder J, Siegmund H, Chevalier T, Bruneval P, Jestin-Mayer G, Delaloge F, Factor C, Mayer JF, Fabicki JM, Robic C, Bonnemain B, Idée JM, Corot C.

Eur J Pharm Sci. 2015 May 25;72:46-56. doi: 10.1016/j.ejps.2015.02.016. Epub 2015 Feb 28.

PMID:
25736527
12.

Safety profiles of gadolinium chelates in juvenile rats differ according to the risk of dissociation.

Fretellier N, Maazouz M, Luseau A, Baudimont F, Jestin-Mayer G, Bourgery S, Rasschaert M, Bruneval P, Factor C, Mecieb F, Idée JM, Corot C.

Reprod Toxicol. 2014 Dec;50:171-9. doi: 10.1016/j.reprotox.2014.10.024. Epub 2014 Nov 5.

PMID:
25462783
13.

The role of gadolinium chelates in the mechanism of nephrogenic systemic fibrosis: A critical update.

Idée JM, Fretellier N, Robic C, Corot C.

Crit Rev Toxicol. 2014 Nov;44(10):895-913. doi: 10.3109/10408444.2014.955568. Epub 2014 Sep 26. Review.

PMID:
25257840
14.

Analytical interference in serum iron determination reveals iron versus gadolinium transmetallation with linear gadolinium-based contrast agents.

Fretellier N, Poteau N, Factor C, Mayer JF, Medina C, Port M, Idée JM, Corot C.

Invest Radiol. 2014 Dec;49(12):766-72. doi: 10.1097/RLI.0000000000000081.

15.

Nephrogenic systemic fibrosis-like effects of magnetic resonance imaging contrast agents in rats with adenine-induced renal failure.

Fretellier N, Bouzian N, Parmentier N, Bruneval P, Jestin G, Factor C, Mandet C, Daubiné F, Massicot F, Laprévote O, Hollenbeck C, Port M, Idée JM, Corot C.

Toxicol Sci. 2013 Jan;131(1):259-70. doi: 10.1093/toxsci/kfs274. Epub 2012 Sep 12. Erratum in: Toxicol Sci. 2013 Mar;132(1):252.

PMID:
22977165
16.

Gadolinium contrast agent associated stimulation of human fibroblast collagen production.

MacNeil S, Bains S, Johnson C, Idée JM, Factor C, Jestin G, Fretellier N, Morcos SK.

Invest Radiol. 2011 Nov;46(11):711-7. doi: 10.1097/RLI.0b013e31822b1f38.

PMID:
21826007
17.

Comparative in vivo dissociation of gadolinium chelates in renally impaired rats: a relaxometry study.

Fretellier N, Idée JM, Dencausse A, Karroum O, Guerret S, Poveda N, Jestin G, Factor C, Raynal I, Zamia P, Port M, Corot C.

Invest Radiol. 2011 May;46(5):292-300. doi: 10.1097/RLI.0b013e3182056ccf.

PMID:
21263333
18.

Clinical, biological, and skin histopathologic effects of ionic macrocyclic and nonionic linear gadolinium chelates in a rat model of nephrogenic systemic fibrosis.

Fretellier N, Idée JM, Guerret S, Hollenbeck C, Hartmann D, González W, Robic C, Port M, Corot C.

Invest Radiol. 2011 Feb;46(2):85-93. doi: 10.1097/RLI.0b013e3181f54044.

PMID:
20938344

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