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Properties of neurons derived from induced pluripotent stem cells of Gaucher disease type 2 patient fibroblasts: potential role in neuropathology.

Sun Y, Florer J, Mayhew CN, Jia Z, Zhao Z, Xu K, Ran H, Liou B, Zhang W, Setchell KD, Gu J, Grabowski GA.

PLoS One. 2015 Mar 30;10(3):e0118771. doi: 10.1371/journal.pone.0118771. eCollection 2015.


Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.

Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, Sabbagh M, Honig LS, Porsteinsson AP, Ferris S, Reichert M, Ketter N, Nejadnik B, Guenzler V, Miloslavsky M, Wang D, Lu Y, Lull J, Tudor IC, Liu E, Grundman M, Yuen E, Black R, Brashear HR; Bapineuzumab 301 and 302 Clinical Trial Investigators.

N Engl J Med. 2014 Jan 23;370(4):322-33. doi: 10.1056/NEJMoa1304839.


Collagen V is a dominant regulator of collagen fibrillogenesis: dysfunctional regulation of structure and function in a corneal-stroma-specific Col5a1-null mouse model.

Sun M, Chen S, Adams SM, Florer JB, Liu H, Kao WW, Wenstrup RJ, Birk DE.

J Cell Sci. 2011 Dec 1;124(Pt 23):4096-105. doi: 10.1242/jcs.091363. Epub 2011 Dec 8.


Regulation of collagen fibril nucleation and initial fibril assembly involves coordinate interactions with collagens V and XI in developing tendon.

Wenstrup RJ, Smith SM, Florer JB, Zhang G, Beason DP, Seegmiller RE, Soslowsky LJ, Birk DE.

J Biol Chem. 2011 Jun 10;286(23):20455-65. doi: 10.1074/jbc.M111.223693. Epub 2011 Apr 5.


Three-dimensional in vitro effects of compression and time in culture on aggregate modulus and on gene expression and protein content of collagen type II in murine chondrocytes.

Chokalingam K, Hunter S, Gooch C, Frede C, Florer J, Wenstrup R, Butler D.

Tissue Eng Part A. 2009 Oct;15(10):2807-16. doi: 10.1089/ten.TEA.2008.0560.


ColVa1 and ColXIa1 are required for myocardial morphogenesis and heart valve development.

Lincoln J, Florer JB, Deutsch GH, Wenstrup RJ, Yutzey KE.

Dev Dyn. 2006 Dec;235(12):3295-305.


Murine model of the Ehlers-Danlos syndrome. col5a1 haploinsufficiency disrupts collagen fibril assembly at multiple stages.

Wenstrup RJ, Florer JB, Davidson JM, Phillips CL, Pfeiffer BJ, Menezes DW, Chervoneva I, Birk DE.

J Biol Chem. 2006 May 5;281(18):12888-95. Epub 2006 Feb 20.


Endogenously expressed multimeric self-cleaving hammerhead ribozymes ablate mutant collagen in cellulo.

Peace BE, Florer JB, Witte D, Smicun Y, Toudjarska I, Wu G, Kilpatrick MW, Tsipouras P, Wenstrup RJ.

Mol Ther. 2005 Jul;12(1):128-36.


Type V collagen controls the initiation of collagen fibril assembly.

Wenstrup RJ, Florer JB, Brunskill EW, Bell SM, Chervoneva I, Birk DE.

J Biol Chem. 2004 Dec 17;279(51):53331-7. Epub 2004 Sep 21.


Mesenchymal stem cells used for rabbit tendon repair can form ectopic bone and express alkaline phosphatase activity in constructs.

Harris MT, Butler DL, Boivin GP, Florer JB, Schantz EJ, Wenstrup RJ.

J Orthop Res. 2004 Sep;22(5):998-1003.


Reduced type I collagen utilization: a pathogenic mechanism in COL5A1 haplo-insufficient Ehlers-Danlos syndrome.

Wenstrup RJ, Florer JB, Cole WG, Willing MC, Birk DE.

J Cell Biochem. 2004 May 1;92(1):113-24.


Enhanced intracellular availability and survival of hammerhead ribozymes increases target ablation in a cellular model of osteogenesis imperfecta.

Smicun Y, Kilpatrick MW, Florer J, Toudjarska I, Wu G, Wenstrup RJ, Tsipouras P.

Gene Ther. 2003 Nov;10(24):2005-12.


Separation of amniotic membranes after amniocentesis in an individual with the classic form of EDS and haploinsufficiency for COL5A1 expression.

Stoler JM, Bromley B, Castro MA, Cole WG, Florer J, Wenstrup RJ.

Am J Med Genet. 2001 Jun 15;101(2):174-7. No abstract available.


COL5A1 haploinsufficiency is a common molecular mechanism underlying the classical form of EDS.

Wenstrup RJ, Florer JB, Willing MC, Giunta C, Steinmann B, Young F, Susic M, Cole WG.

Am J Hum Genet. 2000 Jun;66(6):1766-76. Epub 2000 Apr 24.


Discordant expression of osteoblast markers in MC3T3-E1 cells that synthesize a high turnover matrix.

Wenstrup RJ, Fowlkes JL, Witte DP, Florer JB.

J Biol Chem. 1996 Apr 26;271(17):10271-6.


Abnormal differentiation in MC3T3-E1 preosteoblasts expressing a dominant-negative type I collagen mutation.

Wenstrup RJ, Witte DP, Florer JB.

Connect Tissue Res. 1996;35(1-4):249-57.


Isolation of a novel latent transforming growth factor-beta binding protein gene (LTBP-3).

Yin W, Smiley E, Germiller J, Mecham RP, Florer JB, Wenstrup RJ, Bonadio J.

J Biol Chem. 1995 Apr 28;270(17):10147-60.


Characterization of 1,25-dihydroxyvitamin D3 receptors and in vivo targeting of [3H]-1,25(OH)2D3 in the sheep placenta.

Ross R, Florer J, Halbert K, McIntyre L.

Placenta. 1989 Nov-Dec;10(6):553-67.


Magnesium transport in Salmonella typhimurium: 28Mg2+ transport by the CorA, MgtA, and MgtB systems.

Snavely MD, Florer JB, Miller CG, Maguire ME.

J Bacteriol. 1989 Sep;171(9):4761-6.

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