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Items: 1 to 20 of 113

1.

Delayed differentiation of potent effector CD8+ T cells reducing viremia and reservoir seeding in acute HIV infection.

Takata H, Buranapraditkun S, Kessing C, Fletcher JL, Muir R, Tardif V, Cartwright P, Vandergeeten C, Bakeman W, Nichols CN, Pinyakorn S, Hansasuta P, Kroon E, Chalermchai T, O'Connell R, Kim J, Phanuphak N, Robb ML, Michael NL, Chomont N, Haddad EK, Ananworanich J, Trautmann L; RV254/SEARCH010 and the RV304/SEARCH013 Study Groups..

Sci Transl Med. 2017 Feb 15;9(377). pii: eaag1809. doi: 10.1126/scitranslmed.aag1809.

PMID:
28202771
2.

High Number of Activated CD8+ T Cells Targeting HIV Antigens are Present in Cerebrospinal Fluid in Acute HIV Infection.

Kessing CF, Spudich S, Valcour V, Cartwright P, Chalermchai T, Fletcher JL, Nichols C, Josey BJ, Slike B, Krebs SJ, Sailsuta N, Lerdlum S, Jagodzinski L, Tipsuk S, Suttichom D, Rattanamanee S, Zetterberg H, Hellmuth J, Phanuphak N, Robb ML, Michael NL, Ananworanich J, Trautmann L.

J Acquir Immune Defic Syndr. 2017 Feb 7. doi: 10.1097/QAI.0000000000001301. [Epub ahead of print]

PMID:
28177966
3.

Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection.

Peluso MJ, Valcour V, Phanuphak N, Ananworanich J, Fletcher JL, Chalermchai T, Krebs SJ, Robb ML, Hellmuth J, Gisslén M, Zetterberg H, Spudich S; RV254SEARCH 010, RV304SEARCH 013, and SEARCH 011 Study Teams..

AIDS. 2017 Jan 14;31(2):247-252. doi: 10.1097/QAD.0000000000001314.

PMID:
27819802
4.

Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection.

Sereti I, Krebs SJ, Phanuphak N, Fletcher JL, Slike B, Pinyakorn S, O'Connell RJ, Rupert A, Chomont N, Valcour V, Kim JH, Robb ML, Michael NL, Douek DC, Ananworanich J, Utay NS; RV254/SEARCH 010, RV304/SEARCH 013 and SEARCH 011 protocol teams..

Clin Infect Dis. 2017 Jan 15;64(2):124-131. doi: 10.1093/cid/ciw683.

PMID:
27737952
5.

Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation.

Crowell TA, Fletcher JL, Sereti I, Pinyakorn S, Dewar R, Krebs SJ, Chomchey N, Rerknimitr R, Schuetz A, Michael NL, Phanuphak N, Chomont N, Ananworanich J; RV254/SEARCH010 Study Group..

J Int AIDS Soc. 2016 Sep 15;19(1):21163. doi: 10.7448/IAS.19.1.21163.

6.

Antecedent thermal injury worsens split-thickness skin graft quality: A clinically relevant porcine model of full-thickness burn, excision and grafting.

Carlsson AH, Rose LF, Fletcher JL, Wu JC, Leung KP, Chan RK.

Burns. 2017 Feb;43(1):223-231. doi: 10.1016/j.burns.2016.08.006.

PMID:
27600980
7.

Therapy Development for the Lysosomal Storage Disease Fucosidosis using the Canine Animal Model.

Fletcher JL, Taylor RM.

Pediatr Endocrinol Rev. 2016 Jun;13 Suppl 1:697-706. Review.

PMID:
27491218
8.

HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART.

Ananworanich J, Chomont N, Eller LA, Kroon E, Tovanabutra S, Bose M, Nau M, Fletcher JL, Tipsuk S, Vandergeeten C, O'Connell RJ, Pinyakorn S, Michael N, Phanuphak N, Robb ML; RV217 and RV254/SEARCH010 study groups..

EBioMedicine. 2016 Sep;11:68-72. doi: 10.1016/j.ebiom.2016.07.024.

9.

Impact of early cART in the gut during acute HIV infection.

Deleage C, Schuetz A, Alvord WG, Johnston L, Hao XP, Morcock DR, Rerknimitr R, Fletcher JL, Puttamaswin S, Phanuphak N, Dewar R, McCune JM, Sereti I, Robb M, Kim JH, Schacker TW, Hunt P, Lifson JD, Ananworanich J, Estes JD.

JCI Insight. 2016 Jul 7;1(10). pii: e87065.

10.

Initiation of Antiretroviral Therapy During Acute HIV-1 Infection Leads to a High Rate of Nonreactive HIV Serology.

de Souza MS, Pinyakorn S, Akapirat S, Pattanachaiwit S, Fletcher JL, Chomchey N, Kroon ED, Ubolyam S, Michael NL, Robb ML, Phanuphak P, Kim JH, Phanuphak N, Ananworanich J; RV254/SEARCH010 Study Group..

Clin Infect Dis. 2016 Aug 15;63(4):555-61. doi: 10.1093/cid/ciw365.

PMID:
27317797
11.

Neurologic signs and symptoms frequently manifest in acute HIV infection.

Hellmuth J, Fletcher JL, Valcour V, Kroon E, Ananworanich J, Intasan J, Lerdlum S, Narvid J, Pothisri M, Allen I, Krebs SJ, Slike B, Prueksakaew P, Jagodzinski LL, Puttamaswin S, Phanuphak N, Spudich S; SEARCH 010/RV254 Study Group..

Neurology. 2016 Jul 12;87(2):148-54. doi: 10.1212/WNL.0000000000002837.

PMID:
27287217
12.

Virologic failure is uncommon after treatment initiation during acute HIV infection.

Crowell TA, Phanuphak N, Pinyakorn S, Kroon E, Fletcher JL, Colby D, Tipsuk S, Karnsomlap P, Laopraynak N, O'Connell RJ, Robb ML, Ananworanich J; RV254SEARCH010 Study Group..

AIDS. 2016 Jul 31;30(12):1943-50. doi: 10.1097/QAD.0000000000001148.

PMID:
27163706
13.

Retinoic Acid Receptor γ Regulates B and T Lymphopoiesis via Nestin-Expressing Cells in the Bone Marrow and Thymic Microenvironments.

Joseph C, Nota C, Fletcher JL, Maluenda AC, Green AC, Purton LE.

J Immunol. 2016 Mar 1;196(5):2132-44. doi: 10.4049/jimmunol.1501246.

14.

Markers of HIV reservoir size and immune activation after treatment in acute HIV infection with and without raltegravir and maraviroc intensification.

Ananworanich J, Chomont N, Fletcher JL, Pinyakorn S, Schuetz A, Sereti I, Rerknimitr R, Dewar R, Kroon E, Vandergeeten C, Trichavaroj R, Chomchey N, Chalermchai T, Michael NL, Kim JH, Phanuphak P, Phanuphak N.

J Virus Erad. 2015;1(2):116-122.

15.

Associations between neurologic dysfunction and lesions in canine fucosidosis.

Fletcher JL, Taylor RM.

Genes Brain Behav. 2016 Apr;15(4):420-8. doi: 10.1111/gbb.12282.

PMID:
26711085
16.

Reverse posterior interosseous flap for defects of the dorsal ulnar wrist using previously burned and recently grafted skin.

Baylan JM, Chambers JA, McMullin N, Fletcher JL, Sinha I, Lundy J, King BT, Chan RK.

Burns. 2016 Mar;42(2):e24-30. doi: 10.1016/j.burns.2015.06.020.

PMID:
26652146
17.

Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV.

Valcour VG, Spudich SS, Sailasuta N, Phanuphak N, Lerdlum S, Fletcher JL, Kroon ED, Jagodzinski LL, Allen IE, Adams CL, Prueksakaew P, Slike BM, Hellmuth JM, Kim JH, Ananworanich J; SEARCH 010/RV 254 Study Group..

PLoS One. 2015 Nov 10;10(11):e0142600. doi: 10.1371/journal.pone.0142600.

18.

The effects of intracisternal enzyme replacement versus sham treatment on central neuropathology in preclinical canine fucosidosis.

Kondagari GS, Fletcher JL, Cruz R, Williamson P, Hopwood JJ, Taylor RM.

Orphanet J Rare Dis. 2015 Nov 4;10:143. doi: 10.1186/s13023-015-0357-z.

19.

Neuropsychological Impairment in Acute HIV and the Effect of Immediate Antiretroviral Therapy.

Kore I, Ananworanich J, Valcour V, Fletcher JL, Chalermchai T, Paul R, Reynolds J, Tipsuk S, Ubolyam S, Rattanamanee S, Jagodzinski L, Kim J, Spudich S; RV254/SEARCH 010 Study Group..

J Acquir Immune Defic Syndr. 2015 Dec 1;70(4):393-9. doi: 10.1097/QAI.0000000000000746.

20.

Inability to determine tissue health is main indication of allograft use in intermediate extent burns.

Fletcher JL, Cancio LC, Sinha I, Leung KP, Renz EM, Chan RK.

Burns. 2015 Dec;41(8):1862-7. doi: 10.1016/j.burns.2015.09.006.

PMID:
26471053

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