Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 19

1.

Preclinical Antitumor Activity of a Novel Anti-c-KIT Antibody Drug Conjugate against Mutant and Wild Type c-KIT Positive Solid Tumors.

Abrams TJ, Connor A, Fanton CP, Cohen SB, Huber T, Miller K, Hong EE, Niu X, Kline J, Ison-Dugenny M, Harris S, Walker DB, Krauser KR, Galimi F, Wang Z, Ghoddusi M, Mansfield KG, Lee-Hoeflich ST, Holash J, Pryer N, Kluwe W, Ettenberg SA, Sellers WR, Lees E, Kwon P, Abraham JA, Schleyer S.

Clin Cancer Res. 2018 May 15. pii: clincanres.3795.2017. doi: 10.1158/1078-0432.CCR-17-3795. [Epub ahead of print]

PMID:
29764854
2.

Reply to Second malignancies in Ewing sarcoma survivors.

Marina NM, Liu Q, Donaldson SS, Sklar CA, Armstrong GT, Oeffinger KC, Leisenring WM, Ginsberg JP, Henderson TO, Neglia JP, Stovall MA, Yasui Y, Randall RL, Geller DS, Robison LL, Ness KK.

Cancer. 2017 Oct 15;123(20):4075-4076. doi: 10.1002/cncr.30921. Epub 2017 Aug 24. No abstract available.

PMID:
28837220
3.

Tenosynovial Giant Cell Tumor: Incidence, Prevalence, Patient Characteristics, and Recurrence. A Registry-based Cohort Study in Denmark.

Ehrenstein V, Andersen SL, Qazi I, Sankar N, Pedersen AB, Sikorski R, Acquavella JF.

J Rheumatol. 2017 Oct;44(10):1476-1483. doi: 10.3899/jrheum.160816. Epub 2017 Aug 1.

PMID:
28765257
4.

Enhanced Therapeutic Efficacy and Memory of Tumor-Specific CD8 T Cells by Ex Vivo PI3K-δ Inhibition.

Abu Eid R, Ahmad S, Lin Y, Webb M, Berrong Z, Shrimali R, Kumai T, Ananth S, Rodriguez PC, Celis E, Janik J, Mkrtichyan M, Khleif SN.

Cancer Res. 2017 Aug 1;77(15):4135-4145. doi: 10.1158/0008-5472.CAN-16-1925. Epub 2017 Jun 14.

PMID:
28615225
5.

US immigration order strikes against biotech.

Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci WE, McArthur JG, McCann CM, McCarthy SA, McDonough CG, Mendlein J, Miller L, Miralles D, Moch KI, More B, Myers AG, Narachi MA, Nashat A, Nelson W, Newell WJ, Olle B, Osborn JE, Owens JC, Pande A, Papadopoulos S, Parker HS, Parmar KM, Patterson MR, Paul SM, Perez R, Perry M, Pfeffer CG, Powell M, Pruzanski M, Purcell DJ, Rakhit A, Ramamoorthi K, Rastetter W, Rawcliffe AA, Reid LE, Renaud RC, Rhodes JP, Rieflin WJ, Robins C, Rocklage SM, Rosenblatt M, Rosin JG, Rutter WJ, Saha S, Samuels C, Sato VL, Scangos G, Scarlett JA, Schenkein D, Schreiber SL, Schwab A, Sekhri P, Shah R, Shenk T, Siegall CB, Simon NJ, Simonian N, Stein J, Su M, Szela MT, Taglietti M, Tandon N, Termeer H, Thornberry NA, Tolar M, Ulevitch R, Vaishnaw AK, VanLent A, Varsavsky M, Vlasuk GP, Vounatsos M, Waksal SG, Warma N, Watts RJ, Werber Y, Westphal C, Wierenga W, Williams DE, Williams LR, Xanthopoulos KG, Zohar D, Zweifach SS.

Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. No abstract available.

PMID:
28267733
6.

Lack of evidence for GDF11 as a rejuvenator of aged skeletal muscle satellite cells.

Hinken AC, Powers JM, Luo G, Holt JA, Billin AN, Russell AJ.

Aging Cell. 2016 Jun;15(3):582-4. doi: 10.1111/acel.12475. Epub 2016 Mar 28.

7.

Colony-stimulating factor (CSF) 1 receptor blockade reduces inflammation in human and murine models of rheumatoid arthritis.

Garcia S, Hartkamp LM, Malvar-Fernandez B, van Es IE, Lin H, Wong J, Long L, Zanghi JA, Rankin AL, Masteller EL, Wong BR, Radstake TR, Tak PP, Reedquist KA.

Arthritis Res Ther. 2016 Mar 31;18:75. doi: 10.1186/s13075-016-0973-6.

8.

A phase I, first in human study of FP-1039 (GSK3052230), a novel FGF ligand trap, in patients with advanced solid tumors.

Tolcher AW, Papadopoulos KP, Patnaik A, Wilson K, Thayer S, Zanghi J, Gemo AT, Kavanaugh WM, Keer HN, LoRusso PM.

Ann Oncol. 2016 Mar;27(3):526-32. doi: 10.1093/annonc/mdv591. Epub 2015 Dec 8.

PMID:
26646757
9.

FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase.

Guan J, Umapathy G, Yamazaki Y, Wolfstetter G, Mendoza P, Pfeifer K, Mohammed A, Hugosson F, Zhang H, Hsu AW, Halenbeck R, Hallberg B, Palmer RH.

Elife. 2015 Sep 29;4:e09811. doi: 10.7554/eLife.09811.

10.

Design, synthesis of diaminopyrimidine inhibitors targeting IgE- and IgG-mediated activation of Fc receptor signaling.

Argade A, Bhamidipati S, Li H, Sylvain C, Clough J, Carroll D, Keim H, Braselmann S, Taylor V, Zhao H, Herlaar E, Issakani SD, Wong BR, Masuda ES, Payan DG, Singh R.

Bioorg Med Chem Lett. 2015;25(10):2122-8. doi: 10.1016/j.bmcl.2015.03.072. Epub 2015 Apr 1.

PMID:
25891105
11.

Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome.

Zhang H, Pao LI, Zhou A, Brace AD, Halenbeck R, Hsu AW, Bray TL, Hestir K, Bosch E, Lee E, Wang G, Liu H, Wong BR, Kavanaugh WM, Williams LT.

Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15741-5. doi: 10.1073/pnas.1412009111. Epub 2014 Oct 20.

12.

Lead identification to clinical candidate selection: drugs for Chagas disease.

Neitz RJ, Chen S, Supek F, Yeh V, Kellar D, Gut J, Bryant C, Gallardo-Godoy A, Molteni V, Roach SL, Khare S, Stinson M, Chatterjee AK, Robertson S, Renslo AR, Arkin M, Glynne R, McKerrow J, Siqueira-Neto JL.

J Biomol Screen. 2015 Jan;20(1):101-11. doi: 10.1177/1087057114553103. Epub 2014 Oct 3. Erratum in: J Biomol Screen. 2015 Aug;20(7):927.

PMID:
25281737
13.

Targeting IL-34 in chronic inflammation.

Masteller EL, Wong BR.

Drug Discov Today. 2014 Aug;19(8):1212-6. doi: 10.1016/j.drudis.2014.05.016. Epub 2014 Jun 4. Review.

14.

Human and mouse skeletal muscle stem cells: convergent and divergent mechanisms of myogenesis.

Bareja A, Holt JA, Luo G, Chang C, Lin J, Hinken AC, Freudenberg JM, Kraus WE, Evans WJ, Billin AN.

PLoS One. 2014 Feb 28;9(2):e90398. doi: 10.1371/journal.pone.0090398. eCollection 2014.

15.

Blockade of nonhormonal fibroblast growth factors by FP-1039 inhibits growth of multiple types of cancer.

Harding TC, Long L, Palencia S, Zhang H, Sadra A, Hestir K, Patil N, Levin A, Hsu AW, Charych D, Brennan T, Zanghi J, Halenbeck R, Marshall SA, Qin M, Doberstein SK, Hollenbaugh D, Kavanaugh WM, Williams LT, Baker KP.

Sci Transl Med. 2013 Mar 27;5(178):178ra39. doi: 10.1126/scitranslmed.3005414.

16.

Discovery of a cytokine and its receptor by functional screening of the extracellular proteome.

Lin H, Lee E, Hestir K, Leo C, Huang M, Bosch E, Halenbeck R, Wu G, Zhou A, Behrens D, Hollenbaugh D, Linnemann T, Qin M, Wong J, Chu K, Doberstein SK, Williams LT.

Science. 2008 May 9;320(5877):807-11. doi: 10.1126/science.1154370.

17.

HTS technologies in biopharmaceutical discovery.

Wu G, Doberstein SK.

Drug Discov Today. 2006 Aug;11(15-16):718-24. Review.

PMID:
16846799
18.

Chemical genomics: targets on display.

Doberstein S, Hammond PW, Hubert RS.

Methods Biochem Anal. 2005;45:231-48. Review. No abstract available.

PMID:
19235298
19.

Fibroblast growth factor receptor 1-IIIb is dispensable for skin morphogenesis and wound healing.

Zhang H, Dessimoz J, Beyer TA, Krampert M, Williams LT, Werner S, Grose R.

Eur J Cell Biol. 2004 Feb;83(1):3-11.

PMID:
15085950

Supplemental Content

Loading ...
Support Center