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Items: 1 to 20 of 57

1.

Simultaneous Production of Anabaenopeptins and Namalides by the Cyanobacterium Nostoc sp. CENA543.

Shishido TK, Jokela J, Fewer DP, Wahlsten M, Fiore MF, Sivonen K.

ACS Chem Biol. 2017 Sep 29. doi: 10.1021/acschembio.7b00570. [Epub ahead of print]

PMID:
28933529
2.

Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants.

Alexandru-Crivac CN, Umeobika C, Leikoski N, Jokela J, Rickaby KA, Grilo AM, Sjö P, Plowright AT, Idress M, Siebs E, Nneoyi-Egbe A, Wahlsten M, Sivonen K, Jaspars M, Trembleau L, Fewer DP, Houssen WE.

Chem Commun (Camb). 2017 Sep 26;53(77):10656-10659. doi: 10.1039/c7cc05913b.

PMID:
28905052
3.

Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927.

Pancrace C, Jokela J, Sassoon N, Ganneau C, Desnos-Ollivier M, Wahlsten M, Humisto A, Calteau A, Bay S, Fewer DP, Sivonen K, Gugger M.

ACS Chem Biol. 2017 Jul 21;12(7):1796-1804. doi: 10.1021/acschembio.7b00093. Epub 2017 May 17.

PMID:
28489343
4.

Phylogenomic Analysis of the Microviridin Biosynthetic Pathway Coupled with Targeted Chemo-Enzymatic Synthesis Yields Potent Protease Inhibitors.

Ahmed MN, Reyna-González E, Schmid B, Wiebach V, Süssmuth RD, Dittmann E, Fewer DP.

ACS Chem Biol. 2017 Jun 16;12(6):1538-1546. doi: 10.1021/acschembio.7b00124. Epub 2017 Apr 26.

PMID:
28406289
5.

Genetic Organization of Anabaenopeptin and Spumigin Biosynthetic Gene Clusters in the Cyanobacterium Sphaerospermopsis torques-reginae ITEP-024.

Lima ST, Alvarenga DO, Etchegaray A, Fewer DP, Jokela J, Varani AM, Sanz M, Dörr FA, Pinto E, Sivonen K, Fiore MF.

ACS Chem Biol. 2017 Mar 17;12(3):769-778. doi: 10.1021/acschembio.6b00948. Epub 2017 Jan 26.

PMID:
28085246
6.

Corrigendum: A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway.

Parajuli A, Kwak DH, Dalponte L, Leikoski N, Galica T, Umeobika U, Trembleau L, Bent A, Sivonen K, Wahlsten M, Wang H, Rizzi E, De Bellis G, Naismith J, Jaspars M, Liu X, Houssen W, Fewer DP.

Angew Chem Int Ed Engl. 2017 Jan 9;56(2):433. doi: 10.1002/anie.201609949. No abstract available.

PMID:
28045232
7.

The cyclochlorotine mycotoxin is produced by the nonribosomal peptide synthetase CctN in Talaromyces islandicus ('Penicillium islandicum').

Schafhauser T, Kirchner N, Kulik A, Huijbers MM, Flor L, Caradec T, Fewer DP, Gross H, Jacques P, Jahn L, Jokela J, Leclère V, Ludwig-Müller J, Sivonen K, van Berkel WJ, Weber T, Wohlleben W, van Pée KH.

Environ Microbiol. 2016 Nov;18(11):3728-3741. doi: 10.1111/1462-2920.13294. Epub 2016 Jun 27.

PMID:
26954535
8.

A liquid chromatography-mass spectrometric method for the detection of cyclic β-amino fatty acid lipopeptides.

Urajová P, Hájek J, Wahlsten M, Jokela J, Galica T, Fewer DP, Kust A, Zapomělová-Kozlíková E, Delawská K, Sivonen K, Kopecký J, Hrouzek P.

J Chromatogr A. 2016 Mar 18;1438:76-83. doi: 10.1016/j.chroma.2016.02.013. Epub 2016 Feb 15.

PMID:
26893022
9.

A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway.

Parajuli A, Kwak DH, Dalponte L, Leikoski N, Galica T, Umeobika U, Trembleau L, Bent A, Sivonen K, Wahlsten M, Wang H, Rizzi E, De Bellis G, Naismith J, Jaspars M, Liu X, Houssen W, Fewer DP.

Angew Chem Int Ed Engl. 2016 Mar 7;55(11):3596-9. doi: 10.1002/anie.201509920. Epub 2016 Feb 5. Erratum in: Angew Chem Int Ed Engl. 2017 Jan 9;56(2):433.

10.

Genomic insights into the distribution, genetic diversity and evolution of polyketide synthases and nonribosomal peptide synthetases.

Wang H, Sivonen K, Fewer DP.

Curr Opin Genet Dev. 2015 Dec;35:79-85. doi: 10.1016/j.gde.2015.10.004. Epub 2015 Nov 21. Review.

PMID:
26605685
11.

Antifungal activity improved by coproduction of cyclodextrins and anabaenolysins in Cyanobacteria.

Shishido TK, Jokela J, Kolehmainen CT, Fewer DP, Wahlsten M, Wang H, Rouhiainen L, Rizzi E, De Bellis G, Permi P, Sivonen K.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13669-74. doi: 10.1073/pnas.1510432112. Epub 2015 Oct 16.

12.

Natural Product Biosynthetic Diversity and Comparative Genomics of the Cyanobacteria.

Dittmann E, Gugger M, Sivonen K, Fewer DP.

Trends Microbiol. 2015 Oct;23(10):642-52. doi: 10.1016/j.tim.2015.07.008. Review.

PMID:
26433696
13.

Minimum Information about a Biosynthetic Gene cluster.

Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.

Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. No abstract available.

PMID:
26284661
14.

Draft genome sequence of Talaromyces islandicus ("Penicillium islandicum") WF-38-12, a neglected mold with significant biotechnological potential.

Schafhauser T, Wibberg D, Rückert C, Winkler A, Flor L, van Pée KH, Fewer DP, Sivonen K, Jahn L, Ludwig-Müller J, Caradec T, Jacques P, Huijbers MM, van Berkel WJ, Weber T, Wohlleben W, Kalinowski J.

J Biotechnol. 2015 Oct 10;211:101-2. doi: 10.1016/j.jbiotec.2015.07.004. Epub 2015 Jul 18.

PMID:
26197417
15.

Antifungal compounds from cyanobacteria.

Shishido TK, Humisto A, Jokela J, Liu L, Wahlsten M, Tamrakar A, Fewer DP, Permi P, Andreote AP, Fiore MF, Sivonen K.

Mar Drugs. 2015 Apr 13;13(4):2124-40. doi: 10.3390/md13042124.

16.

Identification of geosmin and 2-methylisoborneol in cyanobacteria and molecular detection methods for the producers of these compounds.

Suurnäkki S, Gomez-Saez GV, Rantala-Ylinen A, Jokela J, Fewer DP, Sivonen K.

Water Res. 2015 Jan 1;68:56-66.

PMID:
25462716
17.

Pseudoaeruginosins, nonribosomal peptides in Nodularia spumigena.

Liu L, Budnjo A, Jokela J, Haug BE, Fewer DP, Wahlsten M, Rouhiainen L, Permi P, Fossen T, Sivonen K.

ACS Chem Biol. 2015 Mar 20;10(3):725-33. doi: 10.1021/cb5004306. Epub 2014 Dec 5.

PMID:
25419633
18.

Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria.

Calteau A, Fewer DP, Latifi A, Coursin T, Laurent T, Jokela J, Kerfeld CA, Sivonen K, Piel J, Gugger M.

BMC Genomics. 2014 Nov 18;15:977. doi: 10.1186/1471-2164-15-977.

19.

4-Methylproline guided natural product discovery: co-occurrence of 4-hydroxy- and 4-methylprolines in nostoweipeptins and nostopeptolides.

Liu L, Jokela J, Herfindal L, Wahlsten M, Sinkkonen J, Permi P, Fewer DP, Døskeland SO, Sivonen K.

ACS Chem Biol. 2014 Nov 21;9(11):2646-55. doi: 10.1021/cb500436p. Epub 2014 Sep 25.

PMID:
25203327
20.

Reply to Sasso et al.: Distribution and phylogeny of nonribosomal peptide and polyketide biosynthetic pathways in eukaryotes.

Wang H, Fewer DP, Holm L, Rouhiainen L, Sivonen K.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):E3947. doi: 10.1073/pnas.1413343111. Epub 2014 Sep 2. No abstract available.

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