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Items: 1 to 20 of 91

1.

Paclitaxel suppresses Tau-mediated microtubule bundling in a concentration-dependent manner.

Choi MC, Chung PJ, Song C, Miller HP, Kiris E, Li Y, Wilson L, Feinstein SC, Safinya CR.

Biochim Biophys Acta. 2016 Sep 12. pii: S0304-4165(16)30345-2. doi: 10.1016/j.bbagen.2016.09.011. [Epub ahead of print]

PMID:
27632200
2.

Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment.

Chung PJ, Song C, Deek J, Miller HP, Li Y, Choi MC, Wilson L, Feinstein SC, Safinya CR.

Nat Commun. 2016 Jul 25;7:12278. doi: 10.1038/ncomms12278.

3.

Oligomerization of the microtubule-associated protein tau is mediated by its N-terminal sequences: implications for normal and pathological tau action.

Feinstein HE, Benbow SJ, LaPointe NE, Patel N, Ramachandran S, Do TD, Gaylord MR, Huskey NE, Dressler N, Korff M, Quon B, Cantrell KL, Bowers MT, Lal R, Feinstein SC.

J Neurochem. 2016 Jun;137(6):939-54. doi: 10.1111/jnc.13604. Epub 2016 Apr 20.

PMID:
26953146
4.

Amyloid β-Protein C-Terminal Fragments: Formation of Cylindrins and β-Barrels.

Do TD, LaPointe NE, Nelson R, Krotee P, Hayden EY, Ulrich B, Quan S, Feinstein SC, Teplow DB, Eisenberg D, Shea JE, Bowers MT.

J Am Chem Soc. 2016 Jan 20;138(2):549-57. doi: 10.1021/jacs.5b09536. Epub 2016 Jan 6.

PMID:
26700445
5.

Effects of wild type tau and disease-linked tau mutations on microtubule organization and intracellular trafficking.

Yu D, Feinstein SC, Valentine MT.

J Biomech. 2016 May 24;49(8):1280-5. doi: 10.1016/j.jbiomech.2015.09.043. Epub 2015 Dec 2.

PMID:
26674472
6.

Effects of Paclitaxel and Eribulin in Mouse Sciatic Nerve: A Microtubule-Based Rationale for the Differential Induction of Chemotherapy-Induced Peripheral Neuropathy.

Benbow SJ, Cook BM, Reifert J, Wozniak KM, Slusher BS, Littlefield BA, Wilson L, Jordan MA, Feinstein SC.

Neurotox Res. 2016 Feb;29(2):299-313. doi: 10.1007/s12640-015-9580-6. Epub 2015 Dec 11.

PMID:
26659667
7.

Amino Acid Metaclusters: Implications of Growth Trends on Peptide Self-Assembly and Structure.

Do TD, de Almeida NE, LaPointe NE, Chamas A, Feinstein SC, Bowers MT.

Anal Chem. 2016 Jan 5;88(1):868-76. doi: 10.1021/acs.analchem.5b03454. Epub 2015 Dec 15.

PMID:
26632663
8.

Opposing Effects of Cucurbit[7]uril and 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranose on Amyloid β25-35 Assembly.

de Almeida NE, Do TD, Tro M, LaPointe NE, Feinstein SC, Shea JE, Bowers MT.

ACS Chem Neurosci. 2016 Feb 17;7(2):218-26. doi: 10.1021/acschemneuro.5b00280. Epub 2015 Dec 10.

PMID:
26629788
9.

Direct force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules.

Chung PJ, Choi MC, Miller HP, Feinstein HE, Raviv U, Li Y, Wilson L, Feinstein SC, Safinya CR.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6416-25. doi: 10.1073/pnas.1513172112. Epub 2015 Nov 5.

10.

Tau Aggregation Propensity Engrained in Its Solution State.

Eschmann NA, Do TD, LaPointe NE, Shea JE, Feinstein SC, Bowers MT, Han S.

J Phys Chem B. 2015 Nov 12;119(45):14421-32. doi: 10.1021/acs.jpcb.5b08092. Epub 2015 Oct 28.

PMID:
26484390
11.

Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3.

Ganguly P, Do TD, Larini L, LaPointe NE, Sercel AJ, Shade MF, Feinstein SC, Bowers MT, Shea JE.

J Phys Chem B. 2015 Apr 2;119(13):4582-93. doi: 10.1021/acs.jpcb.5b00175. Epub 2015 Mar 24.

12.

Regulation and aggregation of intrinsically disordered peptides.

Levine ZA, Larini L, LaPointe NE, Feinstein SC, Shea JE.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2758-63. doi: 10.1073/pnas.1418155112. Epub 2015 Feb 17.

13.

Factors that drive peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants.

Do TD, LaPointe NE, Sangwan S, Teplow DB, Feinstein SC, Sawaya MR, Eisenberg DS, Bowers MT.

J Phys Chem B. 2014 Jul 3;118(26):7247-56. doi: 10.1021/jp502473s. Epub 2014 Jun 18.

14.

Tau proteins harboring neurodegeneration-linked mutations impair kinesin translocation in vitro.

Yu D, LaPointe NE, Guzman E, Pessino V, Wilson L, Feinstein SC, Valentine MT.

J Alzheimers Dis. 2014;39(2):301-14. doi: 10.3233/JAD-131274.

PMID:
24150109
15.

Amyloid β peptide cleavage by kallikrein 7 attenuates fibril growth and rescues neurons from Aβ-mediated toxicity in vitro.

Shropshire TD, Reifert J, Rajagopalan S, Baker D, Feinstein SC, Daugherty PS.

Biol Chem. 2014 Jan;395(1):109-18. doi: 10.1515/hsz-2013-0230.

PMID:
23989112
16.

Effects of pH and charge state on peptide assembly: the YVIFL model system.

Do TD, LaPointe NE, Economou NJ, Buratto SK, Feinstein SC, Shea JE, Bowers MT.

J Phys Chem B. 2013 Sep 19;117(37):10759-68. doi: 10.1021/jp406066d. Epub 2013 Sep 4.

PMID:
23937333
17.

Factors that drive peptide assembly and fibril formation: experimental and theoretical analysis of Sup35 NNQQNY mutants.

Do TD, Economou NJ, LaPointe NE, Kincannon WM, Bleiholder C, Feinstein SC, Teplow DB, Buratto SK, Bowers MT.

J Phys Chem B. 2013 Jul 18;117(28):8436-46. doi: 10.1021/jp4046287. Epub 2013 Jul 9.

PMID:
23802812
18.

Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy.

LaPointe NE, Morfini G, Brady ST, Feinstein SC, Wilson L, Jordan MA.

Neurotoxicology. 2013 Jul;37:231-9. doi: 10.1016/j.neuro.2013.05.008. Epub 2013 May 24.

19.

Initiation of assembly of tau(273-284) and its ΔK280 mutant: an experimental and computational study.

Larini L, Gessel MM, LaPointe NE, Do TD, Bowers MT, Feinstein SC, Shea JE.

Phys Chem Chem Phys. 2013 Jun 21;15(23):8916-28. doi: 10.1039/c3cp00063j. Epub 2013 Mar 20.

20.

Ion specific effects in bundling and depolymerization of taxol-stabilized microtubules.

Needleman DJ, Ojeda-Lopez MA, Raviv U, Miller HP, Li Y, Song C, Feinstein SC, Wilson L, Choi MC, Safinya CR.

Faraday Discuss. 2013;166:31-45.

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