Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 156

1.

The IKs Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry.

Thompson E, Eldstrom J, Westhoff M, McAfee D, Fedida D.

Biophys J. 2018 Sep 27. pii: S0006-3495(18)31072-5. doi: 10.1016/j.bpj.2018.09.018. [Epub ahead of print]

PMID:
30314657
2.

Single channel kinetic analysis of the cAMP effect on IKs mutants, S209F and S27D/S92D.

Thompson E, Eldstrom J, Fedida D.

Channels (Austin). 2018;12(1):276-283. doi: 10.1080/19336950.2018.1499369.

PMID:
30027808
3.

Modeling the Hidden Pathways of IKs Channel Activation.

Fedida D.

Biophys J. 2018 Jul 3;115(1):1-2. doi: 10.1016/j.bpj.2018.05.020. No abstract available.

PMID:
29972801
4.

Probing the molecular basis of hERG drug block with unnatural amino acids.

Macdonald LC, Kim RY, Kurata HT, Fedida D.

Sci Rep. 2018 Jan 10;8(1):289. doi: 10.1038/s41598-017-18448-x.

5.

Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening.

Hou P, Eldstrom J, Shi J, Zhong L, McFarland K, Gao Y, Fedida D, Cui J.

Nat Commun. 2017 Nov 23;8(1):1730. doi: 10.1038/s41467-017-01911-8.

6.

The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues.

Dou Y, Macdonald LC, Wu Y, Fedida D.

Biophys J. 2017 Nov 7;113(9):1979-1991. doi: 10.1016/j.bpj.2017.09.004.

PMID:
29117522
7.

Photo-Cross-Linking of IKs Demonstrates State-Dependent Interactions between KCNE1 and KCNQ1.

Westhoff M, Murray CI, Eldstrom J, Fedida D.

Biophys J. 2017 Jul 25;113(2):415-425. doi: 10.1016/j.bpj.2017.06.005.

8.

cAMP-dependent regulation of IKs single-channel kinetics.

Thompson E, Eldstrom J, Westhoff M, McAfee D, Balse E, Fedida D.

J Gen Physiol. 2017 Aug 7;149(8):781-798. doi: 10.1085/jgp.201611734. Epub 2017 Jul 7.

9.

Binding and Proton Blockage by Amantadine Variants of the Influenza M2WT and M2S31N Explained.

Tzitzoglaki C, Wright A, Freudenberger K, Hoffmann A, Tietjen I, Stylianakis I, Kolarov F, Fedida D, Schmidtke M, Gauglitz G, Cross TA, Kolocouris A.

J Med Chem. 2017 Mar 9;60(5):1716-1733. doi: 10.1021/acs.jmedchem.6b01115. Epub 2017 Feb 15.

PMID:
28107633
10.

Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase.

Bround MJ, Wambolt R, Cen H, Asghari P, Albu RF, Han J, McAfee D, Pourrier M, Scott NE, Bohunek L, Kulpa JE, Chen SR, Fedida D, Brownsey RW, Borchers CH, Foster LJ, Mayor T, Moore ED, Allard MF, Johnson JD.

J Biol Chem. 2016 Nov 4;291(45):23490-23505. Epub 2016 Sep 12.

11.

Novel Acylguanidine-Based Inhibitor of HIV-1.

Mwimanzi P, Tietjen I, Miller SC, Shahid A, Cobarrubias K, Kinloch NN, Baraki B, Richard J, Finzi A, Fedida D, Brumme ZL, Brockman MA.

J Virol. 2016 Sep 29;90(20):9495-508. doi: 10.1128/JVI.01107-16. Print 2016 Oct 15.

12.

hERG long QT syndrome type 2 mutants need more than a chaperone to dance.

Fedida D, Macdonald L.

J Physiol. 2016 Aug 1;594(15):4095-6. doi: 10.1113/JP272417. No abstract available.

13.

Croton megalobotrys Müll Arg. and Vitex doniana (Sweet): Traditional medicinal plants in a three-step treatment regimen that inhibit in vitro replication of HIV-1.

Tietjen I, Gatonye T, Ngwenya BN, Namushe A, Simonambanga S, Muzila M, Mwimanzi P, Xiao J, Fedida D, Brumme ZL, Brockman MA, Andrae-Marobela K.

J Ethnopharmacol. 2016 Sep 15;191:331-340. doi: 10.1016/j.jep.2016.06.040. Epub 2016 Jun 24.

PMID:
27350006
14.

Mechanisms of Action of Novel Influenza A/M2 Viroporin Inhibitors Derived from Hexamethylene Amiloride.

Jalily PH, Eldstrom J, Miller SC, Kwan DC, Tai SS, Chou D, Niikura M, Tietjen I, Fedida D.

Mol Pharmacol. 2016 Aug;90(2):80-95. doi: 10.1124/mol.115.102731. Epub 2016 May 18.

15.

AMP-activated protein kinase inhibits Kv 1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation.

Moral-Sanz J, Mahmoud AD, Ross FA, Eldstrom J, Fedida D, Hardie DG, Evans AM.

J Physiol. 2016 Sep 1;594(17):4901-15. doi: 10.1113/JP272032. Epub 2016 Jun 30.

16.

Office hysteroscopy: A report of 2402 cases.

Capmas P, Pourcelot AG, Giral E, Fedida D, Fernandez H.

J Gynecol Obstet Biol Reprod (Paris). 2016 May;45(5):445-50. doi: 10.1016/j.jgyn.2016.02.007. Epub 2016 Apr 4.

17.

Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4.

Murray CI, Westhoff M, Eldstrom J, Thompson E, Emes R, Fedida D.

Elife. 2016 Jan 23;5. pii: e11815. doi: 10.7554/eLife.11815.

18.

De Novo Mutation in the SCN5A Gene Associated with Brugada Syndrome.

Wang L, Meng X, Yuchi Z, Zhao Z, Xu D, Fedida D, Wang Z, Huang C.

Cell Physiol Biochem. 2015;36(6):2250-62. doi: 10.1159/000430189. Epub 2015 Jul 24.

19.

Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors.

Tietjen I, Ntie-Kang F, Mwimanzi P, Onguéné PA, Scull MA, Idowu TO, Ogundaini AO, Meva'a LM, Abegaz BM, Rice CM, Andrae-Marobela K, Brockman MA, Brumme ZL, Fedida D.

PLoS One. 2015 Apr 1;10(4):e0121099. doi: 10.1371/journal.pone.0121099. eCollection 2015.

20.

Sequence of gating charge movement and pore gating in HERG activation and deactivation pathways.

Goodchild SJ, Macdonald LC, Fedida D.

Biophys J. 2015 Mar 24;108(6):1435-1447. doi: 10.1016/j.bpj.2015.02.014.

Supplemental Content

Loading ...
Support Center