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The use of cellular thermal shift assay (CETSA) to study Crizotinib resistance in ALK-expressing human cancers.

Alshareef A, Zhang HF, Huang YH, Wu C, Zhang JD, Wang P, El-Sehemy A, Fares M, Lai R.

Sci Rep. 2016 Sep 19;6:33710. doi: 10.1038/srep33710.


Essentiality Is a Strong Determinant of Protein Rates of Evolution during Mutation Accumulation Experiments in Escherichia coli.

Alvarez-Ponce D, Sabater-Muñoz B, Toft C, Ruiz-González MX, Fares MA.

Genome Biol Evol. 2016 Sep 26;8(9):2914-2927.


The Molecular Chaperone DnaK Is a Source of Mutational Robustness.

Aguilar-Rodríguez J, Sabater-Muñoz B, Montagud-Martínez R, Berlanga V, Alvarez-Ponce D, Wagner A, Fares MA.

Genome Biol Evol. 2016 Oct 5;8(9):2979-2991.


Synthesis and Cytotoxic Activity of Biphenylurea Derivatives Containing Indolin-2-one Moieties.

Eldehna WM, Fares M, Ibrahim HS, Alsherbiny MA, Aly MH, Ghabbour HA, Abdel-Aziz HA.

Molecules. 2016 Jun 10;21(6). pii: E762. doi: 10.3390/molecules21060762.


Systematic Reviews and Meta-analyses for Cardiology Fellows.

Fares M, Alahdab F, Alsaied T.

Congenit Heart Dis. 2016 Jul;11(4):369-71. doi: 10.1111/chd.12377. Epub 2016 May 27.


Harmonization of the Volume of Interest Delineation among All Eleven Radiotherapy Centers in the North of France.

Pasquier D, Boutaud de la Combe-Chossiere L, Carlier D, Darloy F, Degrendel-Courtecuisse AC, Dufour C, Fares M, Gilbeau L, Liem X, Martin P, Meyer P, Minne JF, Olszyk O, Rhliouch H, Tokarski M, Viot C, Castelain B, Lartigau E.

PLoS One. 2016 Mar 17;11(3):e0150917. doi: 10.1371/journal.pone.0150917. eCollection 2016.


Commentary: Impact of a deletion of the full-length and short isoform of p75NTR on cholinergic innervation and the population of postmitotic doublecortin positive cells in the dentate gyrus.

Sabry MA, Fares M, Folkesson R, Al-Ramadan M, Alabkal J, Al-Kafaji G, Hassan M.

Front Neuroanat. 2016 Feb 19;10:14. doi: 10.3389/fnana.2016.00014. eCollection 2016. No abstract available.


Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII.

Eldehna WM, Fares M, Ceruso M, Ghabbour HA, Abou-Seri SM, Abdel-Aziz HA, Abou El Ella DA, Supuran CT.

Eur J Med Chem. 2016 Mar 3;110:259-66. doi: 10.1016/j.ejmech.2016.01.030. Epub 2016 Jan 20.


Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson's disease.

Fares MB, Maco B, Oueslati A, Rockenstein E, Ninkina N, Buchman VL, Masliah E, Lashuel HA.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E912-21. doi: 10.1073/pnas.1512876113. Epub 2016 Feb 2.


Synthesis, Biological Evaluation and Molecular Docking of Certain Sulfones as Potential Nonazole Antifungal Agents.

Fares M, Said MA, Alsherbiny MA, Eladwy RA, Almahli H, Abdel-Aziz MM, Ghabbour HA, Eldehna WM, Abdel-Aziz HA.

Molecules. 2016 Jan 20;21(1):E114. doi: 10.3390/molecules21010114.


Evolution by gene duplication of Medicago truncatula PISTILLATA-like transcription factors.

Roque E, Fares MA, Yenush L, Rochina MC, Wen J, Mysore KS, Gómez-Mena C, Beltrán JP, Cañas LA.

J Exp Bot. 2016 Mar;67(6):1805-17. doi: 10.1093/jxb/erv571. Epub 2016 Jan 15.


Introduction: The transition from milestones to innovations.

Fares MA.

Cleve Clin J Med. 2015 Dec;82(12 Suppl 2):S5. doi: 10.3949/ccjm.82.s2.01. No abstract available.


Safety of Desmodium adscendens extract on hepatocytes and renal cells. Protective effect against oxidative stress.

François C, Fares M, Baiocchi C, Maixent JM.

J Intercult Ethnopharmacol. 2015 Jan-Mar;4(1):1-5. doi: 10.5455/jice.20141013041312. Epub 2014 Nov 28.


Synthesis, in Vitro and in Silico Studies of Some Novel 5-Nitrofuran-2-yl Hydrazones as Antimicrobial and Antitubercular Agents.

Abdel-Aziz HA, Eldehna WM, Fares M, Elsaman T, Abdel-Aziz MM, Soliman DH.

Biol Pharm Bull. 2015;38(10):1617-30. doi: 10.1248/bpb.b15-00439. Epub 2015 Jul 8.


Functional conservation of an ancestral Pellino protein in helminth species.

Cluxton CD, Caffrey BE, Kinsella GK, Moynagh PN, Fares MA, Fallon PG.

Sci Rep. 2015 Jun 29;5:11687. doi: 10.1038/srep11687.


Fitness Trade-Offs Determine the Role of the Molecular Chaperonin GroEL in Buffering Mutations.

Sabater-Muñoz B, Prats-Escriche M, Montagud-Martínez R, López-Cerdán A, Toft C, Aguilar-Rodríguez J, Wagner A, Fares MA.

Mol Biol Evol. 2015 Oct;32(10):2681-93. doi: 10.1093/molbev/msv144. Epub 2015 Jun 27.


Anti-Inflammatory and Cytostatic Activities of a Parthenolide-Like Sesquiterpene Lactone from Cota palaestina subsp. syriaca.

Talhouk RS, Nasr B, Fares MB, Ajeeb B, Nahhas R, Al Aaraj L, Talhouk SN, Ghaddar TH, Saliba NA.

Evid Based Complement Alternat Med. 2015;2015:474597. doi: 10.1155/2015/474597. Epub 2015 May 19.


Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking.

Eldehna WM, Fares M, Ibrahim HS, Aly MH, Zada S, Ali MM, Abou-Seri SM, Abdel-Aziz HA, Abou El Ella DA.

Eur J Med Chem. 2015 Jul 15;100:89-97. doi: 10.1016/j.ejmech.2015.05.040. Epub 2015 May 31.


DNA damage, lysosomal degradation and Bcl-xL deamidation in doxycycline- and minocycline-induced cell death in the K562 leukemic cell line.

Fares M, Abedi-Valugerdi M, Hassan M, Potácová Z.

Biochem Biophys Res Commun. 2015 Jul 31;463(3):268-74. doi: 10.1016/j.bbrc.2015.05.043. Epub 2015 May 27.


The origins of mutational robustness.

Fares MA.

Trends Genet. 2015 Jul;31(7):373-81. doi: 10.1016/j.tig.2015.04.008. Epub 2015 May 23. Review.

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