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Items: 6


A cholinergic-sympathetic pathway primes immunity in hypertension and mediates brain-to-spleen communication.

Carnevale D, Perrotta M, Pallante F, Fardella V, Iacobucci R, Fardella S, Carnevale L, Carnevale R, De Lucia M, Cifelli G, Lembo G.

Nat Commun. 2016 Sep 27;7:13035. doi: 10.1038/ncomms13035.


PI3Kγ Inhibition Protects Against Diabetic Cardiomyopathy in Mice.

Maffei A, Cifelli G, Carnevale R, Iacobucci R, Pallante F, Fardella V, Fardella S, Hirsch E, Lembo G, Carnevale D.

Rev Esp Cardiol (Engl Ed). 2017 Jan;70(1):16-24. doi: 10.1016/j.rec.2016.04.034. English, Spanish.


TIMP3 interplays with apelin to regulate cardiovascular metabolism in hypercholesterolemic mice.

Stöhr R, Kappel BA, Carnevale D, Cavalera M, Mavilio M, Arisi I, Fardella V, Cifelli G, Casagrande V, Rizza S, Cattaneo A, Mauriello A, Menghini R, Lembo G, Federici M.

Mol Metab. 2015 Aug 6;4(10):741-52. doi: 10.1016/j.molmet.2015.07.007.


Lack of kinase-independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling.

D'Andrea I, Fardella V, Fardella S, Pallante F, Ghigo A, Iacobucci R, Maffei A, Hirsch E, Lembo G, Carnevale D.

EMBO Mol Med. 2015 Apr 16;7(7):904-17. doi: 10.15252/emmm.201404697.


The angiogenic factor PlGF mediates a neuroimmune interaction in the spleen to allow the onset of hypertension.

Carnevale D, Pallante F, Fardella V, Fardella S, Iacobucci R, Federici M, Cifelli G, De Lucia M, Lembo G.

Immunity. 2014 Nov 20;41(5):737-52. doi: 10.1016/j.immuni.2014.11.002.


Hypertension induces brain β-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature.

Carnevale D, Mascio G, D'Andrea I, Fardella V, Bell RD, Branchi I, Pallante F, Zlokovic B, Yan SS, Lembo G.

Hypertension. 2012 Jul;60(1):188-97. doi: 10.1161/HYPERTENSIONAHA.112.195511.

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