Send to

Choose Destination

See 1 citation found by title matching your search:

See comment in PubMed Commons below
Trends Cell Biol. 2005 Feb;15(2):84-91.

FRAP analysis of binding: proper and fitting.

Author information

  • 1Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, Bethesda, MD 20892, USA.


Dynamic molecular interactions are fundamental to all cellular processes. In vivo analyses of these interactions are frequently done using fluorescence recovery after photobleaching (FRAP). Proper interpretation of FRAP data yields information about the binding interactions of fluorescently tagged molecules, including the number of binding states and the binding strength of each state. This binding information can be gleaned from appropriate models of the process underlying a FRAP recovery. Continued application and development of these approaches promise to provide crucial information for a quantitative description of the molecular networks that regulate cellular function.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center