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1.
2.

Biomarkers of β-Cell Stress and Death in Type 1 Diabetes.

Mirmira RG, Sims EK, Syed F, Evans-Molina C.

Curr Diab Rep. 2016 Oct;16(10):95. doi: 10.1007/s11892-016-0783-x. Review.

PMID:
27541297
3.

SERCA2 Deficiency Impairs Pancreatic β-Cell Function in Response to Diet-Induced Obesity.

Tong X, Kono T, Anderson-Baucum EK, Yamamoto W, Gilon P, Lebeche D, Day RN, Shull GE, Evans-Molina C.

Diabetes. 2016 Oct;65(10):3039-52. doi: 10.2337/db16-0084.

PMID:
27489309
4.

Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes.

Sims EK, Chaudhry Z, Watkins R, Syed F, Blum J, Ouyang F, Perkins SM, Mirmira RG, Sosenko J, DiMeglio LA, Evans-Molina C.

Diabetes Care. 2016 Sep;39(9):1519-26. doi: 10.2337/dc15-2849.

PMID:
27385327
5.

Nucleic acid biomarkers of β cell stress and death in type 1 diabetes.

Syed F, Evans-Molina C.

Curr Opin Endocrinol Diabetes Obes. 2016 Aug;23(4):312-7. doi: 10.1097/MED.0000000000000261.

PMID:
27254268
6.

The relationship between BMI and insulin resistance and progression from single to multiple autoantibody positivity and type 1 diabetes among TrialNet Pathway to Prevention participants.

Meah FA, DiMeglio LA, Greenbaum CJ, Blum JS, Sosenko JM, Pugliese A, Geyer S, Xu P, Evans-Molina C; Type 1 Diabetes TrialNet Study Group..

Diabetologia. 2016 Jun;59(6):1186-95. doi: 10.1007/s00125-016-3924-5.

PMID:
26995649
8.

HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression.

Pugliese A, Boulware D, Yu L, Babu S, Steck AK, Becker D, Rodriguez H, DiMeglio L, Evans-Molina C, Harrison LC, Schatz D, Palmer JP, Greenbaum C, Eisenbarth GS, Sosenko JM; Type 1 Diabetes TrialNet Study Group..

Diabetes. 2016 Apr;65(4):1109-19. doi: 10.2337/db15-1105.

9.

Intranasal Glucagon for Treatment of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes: A Randomized Crossover Noninferiority Study.

Rickels MR, Ruedy KJ, Foster NC, Piché CA, Dulude H, Sherr JL, Tamborlane WV, Bethin KE, DiMeglio LA, Wadwa RP, Ahmann AJ, Haller MJ, Nathan BM, Marcovina SM, Rampakakis E, Meng L, Beck RW; T1D Exchange Intranasal Glucagon Investigators..

Diabetes Care. 2016 Feb;39(2):264-70. doi: 10.2337/dc15-1498.

PMID:
26681725
10.

CD40 promotes MHC class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity.

Morris DL, Oatmen KE, Mergian TA, Cho KW, DelProposto JL, Singer K, Evans-Molina C, O'Rourke RW, Lumeng CN.

J Leukoc Biol. 2016 Jun;99(6):1107-19. doi: 10.1189/jlb.3A0115-009R.

PMID:
26658005
11.

Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells.

Xiong X, Wang G, Tao R, Wu P, Kono T, Li K, Ding WX, Tong X, Tersey SA, Harris RA, Mirmira RG, Evans-Molina C, Dong XC.

Diabetologia. 2016 Jan;59(1):151-60.

12.

Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes.

Watkins RA, Evans-Molina C, Terrell JK, Day KH, Guindon L, Restrepo IA, Mirmira RG, Blum JS, DiMeglio LA.

Transl Res. 2016 Feb;168:96-106.e1. doi: 10.1016/j.trsl.2015.08.010.

PMID:
26397425
13.

Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes.

Fisher MM, Watkins RA, Blum J, Evans-Molina C, Chalasani N, DiMeglio LA, Mather KJ, Tersey SA, Mirmira RG.

Diabetes. 2015 Nov;64(11):3867-72. doi: 10.2337/db15-0430.

14.
15.

SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet β Cell.

Fujimaki K, Ogihara T, Morris DL, Oda H, Iida H, Fujitani Y, Mirmira RG, Evans-Molina C, Watada H.

J Biol Chem. 2015 Jul 3;290(27):16607-18. doi: 10.1074/jbc.M115.661777.

16.

Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes.

Filgueiras LR, Brandt SL, Wang S, Wang Z, Morris DL, Evans-Molina C, Mirmira RG, Jancar S, Serezani CH.

Sci Signal. 2015 Jan 27;8(361):ra10. doi: 10.1126/scisignal.2005568.

17.

Pancreatic and Islet Development and Function: The Role of Thyroid Hormone.

Mastracci TL, Evans-Molina C.

J Endocrinol Diabetes Obes. 2014;2(3). pii: 1044.

18.

From immunobiology to β-cell biology: the changing perspective on type 1 diabetes.

Maganti A, Evans-Molina C, Mirmira R.

Islets. 2014;6(2):e28778. doi: 10.4161/isl.28778.

19.

Fetal hyperglycemia and a high-fat diet contribute to aberrant glucose tolerance and hematopoiesis in adult rats.

Blue EK, Ballman K, Boyle F, Oh E, Kono T, Quinney SK, Thurmond DC, Evans-Molina C, Haneline LS.

Pediatr Res. 2015 Feb;77(2):316-25. doi: 10.1038/pr.2014.185.

20.

Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell.

Johnson JS, Kono T, Tong X, Yamamoto WR, Zarain-Herzberg A, Merrins MJ, Satin LS, Gilon P, Evans-Molina C.

J Biol Chem. 2014 Nov 21;289(47):32798-810. doi: 10.1074/jbc.M114.575191.

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