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Items: 1 to 20 of 373


Epigenome-based cancer risk prediction: rationale, opportunities and challenges.

Widschwendter M, Jones A, Evans I, Reisel D, Dillner J, Sundström K, Steyerberg EW, Vergouwe Y, Wegwarth O, Rebitschek FG, Siebert U, Sroczynski G, de Beaufort ID, Bolt I, Cibula D, Zikan M, Bjørge L, Colombo N, Harbeck N, Dudbridge F, Tasse AM, Knoppers BM, Joly Y, Teschendorff AE, Pashayan N; FORECEE (4C) Consortium.

Nat Rev Clin Oncol. 2018 Feb 27. doi: 10.1038/nrclinonc.2018.30. [Epub ahead of print] Review.


Diverse functions of clusterin promote and protect against the development of pulmonary fibrosis.

Peix L, Evans IC, Pearce DR, Simpson JK, Maher TM, McAnulty RJ.

Sci Rep. 2018 Jan 30;8(1):1906. doi: 10.1038/s41598-018-20316-1.


The potential of circulating tumor DNA methylation analysis for the early detection and management of ovarian cancer.

Widschwendter M, Zikan M, Wahl B, Lempiäinen H, Paprotka T, Evans I, Jones A, Ghazali S, Reisel D, Eichner J, Rujan T, Yang Z, Teschendorff AE, Ryan A, Cibula D, Menon U, Wittenberger T.

Genome Med. 2017 Dec 22;9(1):116. doi: 10.1186/s13073-017-0500-7.


Methylation patterns in serum DNA for early identification of disseminated breast cancer.

Widschwendter M, Evans I, Jones A, Ghazali S, Reisel D, Ryan A, Gentry-Maharaj A, Zikan M, Cibula D, Eichner J, Alunni-Fabbroni M, Koch J, Janni WJ, Paprotka T, Wittenberger T, Menon U, Wahl B, Rack B, Lempiäinen H.

Genome Med. 2017 Dec 22;9(1):115. doi: 10.1186/s13073-017-0499-9.


Intentional and Unintentional Medication Non-Adherence in Psoriasis: The Role of Patients' Medication Beliefs and Habit Strength.

Thorneloe RJ, Griffiths CEM, Emsley R, Ashcroft DM, Cordingley L; British Association of Dermatologists Biologic Interventions Register; Psoriasis Stratification to Optimise Relevant Therapy Study Groups.

J Invest Dermatol. 2017 Nov 26. pii: S0022-202X(17)33171-8. doi: 10.1016/j.jid.2017.11.015. [Epub ahead of print]


Location and orientation of lone pairs in apatite-type materials: a computational study.

Peet JR, Piovano A, Johnson MR, Evans IR.

Dalton Trans. 2017 Nov 28;46(46):15996-15999. doi: 10.1039/c7dt03956e.


Uncovering protein-protein interactions through a team-based undergraduate biochemistry course.

Cookmeyer DL, Winesett ES, Kokona B, Huff AR, Aliev S, Bloch NB, Bulos JA, Evans IL, Fagre CR, Godbe KN, Khromava M, Konstantinovsky DM, Lafrance AE, Lamacki AJ, Parry RC, Quinn JM, Thurston AM, Tsai KJS, Mollo A, Cryle MJ, Fairman R, Charkoudian LK.

PLoS Biol. 2017 Nov 1;15(11):e2003145. doi: 10.1371/journal.pbio.2003145. eCollection 2017 Nov.


Differential Drug Survival of Second-Line Biologic Therapies in Patients with Psoriasis: Observational Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

Iskandar IYK, Warren RB, Lunt M, Mason KJ, Evans I, McElhone K, Smith CH, Reynolds NJ, Ashcroft DM, Griffiths CEM; BADBIR Study Group.

J Invest Dermatol. 2017 Dec 6. pii: S0022-202X(17)33068-3. doi: 10.1016/j.jid.2017.09.044. [Epub ahead of print]


Epidemiology of Sepsis Among Adolescents at Community Hospital Emergency Departments: Implications for Rory's Regulations.

Evans IVR, Watson RS, Carcillo J, Angus DC, Seymour CW.

JAMA Pediatr. 2017 Oct 1;171(10):1011-1012. doi: 10.1001/jamapediatrics.2017.1915. No abstract available.


Structure and physicochemical characterization of a naproxen-picolinamide cocrystal.

Kerr HE, Softley LK, Suresh K, Hodgkinson P, Evans IR.

Acta Crystallogr C Struct Chem. 2017 Mar 1;73(Pt 3):168-175. doi: 10.1107/S2053229616011980. Epub 2017 Feb 6.


Vascular Endothelial Growth Factor (VEGF) Promotes Assembly of the p130Cas Interactome to Drive Endothelial Chemotactic Signaling and Angiogenesis.

Evans IM, Kennedy SA, Paliashvili K, Santra T, Yamaji M, Lovering RC, Britton G, Frankel P, Kolch W, Zachary IC.

Mol Cell Proteomics. 2017 Feb;16(2):168-180. doi: 10.1074/mcp.M116.064428. Epub 2016 Dec 22.


Bronchiectasis Severity Is an Independent Risk Factor for Vascular Disease in a Bronchiectasis Cohort.

Evans IE, Bedi P, Quinn TM, Hill AT.

Chest. 2017 Feb;151(2):383-388. doi: 10.1016/j.chest.2016.09.022. Epub 2016 Oct 6.


Patterns of biologic therapy use in the management of psoriasis: cohort study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

Iskandar IYK, Ashcroft DM, Warren RB, Evans I, McElhone K, Owen CM, Burden AD, Smith CH, Reynolds NJ, Griffiths CEM.

Br J Dermatol. 2017 May;176(5):1297-1307. doi: 10.1111/bjd.15027. Epub 2017 Mar 20.


Imatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling.

Frolov A, Evans IM, Li N, Sidlauskas K, Paliashvili K, Lockwood N, Barrett A, Brandner S, Zachary IC, Frankel P.

Sci Rep. 2016 Jun 13;6:27378. doi: 10.1038/srep27378.


An Exhaustive Symmetry Approach to Structure Determination: Phase Transitions in Bi2Sn2O7.

Lewis JW, Payne JL, Evans IR, Stokes HT, Campbell BJ, Evans JS.

J Am Chem Soc. 2016 Jun 29;138(25):8031-42. doi: 10.1021/jacs.6b04947. Epub 2016 Jun 15.


Corpse Engulfment Generates a Molecular Memory that Primes the Macrophage Inflammatory Response.

Weavers H, Evans IR, Martin P, Wood W.

Cell. 2016 Jun 16;165(7):1658-1671. doi: 10.1016/j.cell.2016.04.049. Epub 2016 May 19.


Bapineuzumab for mild to moderate Alzheimer's disease in two global, randomized, phase 3 trials.

Vandenberghe R, Rinne JO, Boada M, Katayama S, Scheltens P, Vellas B, Tuchman M, Gass A, Fiebach JB, Hill D, Lobello K, Li D, McRae T, Lucas P, Evans I, Booth K, Luscan G, Wyman BT, Hua L, Yang L, Brashear HR, Black RS; Bapineuzumab 3000 and 3001 Clinical Study Investigators.

Alzheimers Res Ther. 2016 May 12;8(1):18. doi: 10.1186/s13195-016-0189-7.


Hemotin, a Regulator of Phagocytosis Encoded by a Small ORF and Conserved across Metazoans.

Pueyo JI, Magny EG, Sampson CJ, Amin U, Evans IR, Bishop SA, Couso JP.

PLoS Biol. 2016 Mar 25;14(3):e1002395. doi: 10.1371/journal.pbio.1002395. eCollection 2016 Mar.


Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis.

Evans IC, Barnes JL, Garner IM, Pearce DR, Maher TM, Shiwen X, Renzoni EA, Wells AU, Denton CP, Laurent GJ, Abraham DJ, McAnulty RJ.

Clin Sci (Lond). 2016 Apr;130(8):575-86. doi: 10.1042/CS20150697. Epub 2016 Jan 7.


Automated Processing of Plasma Samples for Lipoprotein Separation by Rate-Zonal Ultracentrifugation.

Peters CN, Evans IE.

J Lab Autom. 2016 Dec;21(6):756-764. Epub 2015 Dec 23.


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