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Items: 1 to 20 of 118


Implementation of Mass Cytometry as a Tool for Mechanism of Action Studies in Inflammatory Bowel Disease.

Tyler CJ, Pérez-Jeldres T, Ehinger E, Capaldo B, Karuppuchamy T, Boyer JD, Patel D, Dulai P, Boland BS, Lannigan J, Eckmann L, Ernst PB, Sandborn WJ, Ho SB, Rivera-Nieves J.

Inflamm Bowel Dis. 2018 Jun 8. doi: 10.1093/ibd/izy214. [Epub ahead of print]


Of mice, men and immunity: a case for evolutionary systems biology.

Ernst PB, Carvunis AR.

Nat Immunol. 2018 May;19(5):421-425. doi: 10.1038/s41590-018-0084-4. No abstract available.


Mucosal Mesenchymal Cells: Secondary Barrier and Peripheral Educator for the Gut Immune System.

Kurashima Y, Yamamoto D, Nelson S, Uematsu S, Ernst PB, Nakayama T, Kiyono H.

Front Immunol. 2017 Dec 13;8:1787. doi: 10.3389/fimmu.2017.01787. eCollection 2017. Review.


ELMO1 Regulates Autophagy Induction and Bacterial Clearance During Enteric Infection.

Sarkar A, Tindle C, Pranadinata RF, Reed S, Eckmann L, Stappenbeck TS, Ernst PB, Das S.

J Infect Dis. 2017 Dec 19;216(12):1655-1666. doi: 10.1093/infdis/jix528.


Oxidative Stress Resulting From Helicobacter pylori Infection Contributes to Gastric Carcinogenesis.

Butcher LD, den Hartog G, Ernst PB, Crowe SE.

Cell Mol Gastroenterol Hepatol. 2017 Feb 20;3(3):316-322. doi: 10.1016/j.jcmgh.2017.02.002. eCollection 2017 May. Review.


Our New President- Sheila E. Crowe, MD.

Ernst PB.

Gastroenterology. 2017 May;152(6):1599-1604. doi: 10.1053/j.gastro.2017.03.028. Epub 2017 Mar 29. No abstract available.


Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease.

Chu H, Khosravi A, Kusumawardhani IP, Kwon AH, Vasconcelos AC, Cunha LD, Mayer AE, Shen Y, Wu WL, Kambal A, Targan SR, Xavier RJ, Ernst PB, Green DR, McGovern DP, Virgin HW, Mazmanian SK.

Science. 2016 May 27;352(6289):1116-20. doi: 10.1126/science.aad9948. Epub 2016 May 5.


ELMO1 has an essential role in the internalization of Salmonella Typhimurium into enteric macrophages that impacts disease outcome.

Das S, Sarkar A, Choudhury SS, Owen KA, Castillo V, Fox S, Eckmann L, Elliott MR, Casanova JE, Ernst PB.

Cell Mol Gastroenterol Hepatol. 2015 Apr 1;1(3):311-324.


Regulation of Rac1 and Reactive Oxygen Species Production in Response to Infection of Gastrointestinal Epithelia.

den Hartog G, Chattopadhyay R, Ablack A, Hall EH, Butcher LD, Bhattacharyya A, Eckmann L, Harris PR, Das S, Ernst PB, Crowe SE.

PLoS Pathog. 2016 Jan 13;12(1):e1005382. doi: 10.1371/journal.ppat.1005382. eCollection 2016 Jan.


The role of C1q in recognition of apoptotic epithelial cells and inflammatory cytokine production by phagocytes during Helicobacter pylori infection.

Fox S, Ryan KA, Berger AH, Petro K, Das S, Crowe SE, Ernst PB.

J Inflamm (Lond). 2015 Sep 8;12:51. doi: 10.1186/s12950-015-0098-8. eCollection 2015.


Validation of gene expression biomarker analysis for biopsy-based clinical trials in Crohn's disease.

Boland BS, Boyle DL, Sandborn WJ, Firestein GS, Levesque BG, Hillman J, Zhang B, Proudfoot J, Eckmann L, Ernst PB, Rivera-Nieves J, Pola S, Copur-Dahi N, Zou G, Chang JT.

Inflamm Bowel Dis. 2015 Feb;21(2):323-30. doi: 10.1097/MIB.0000000000000264.


Validated gene expression biomarker analysis for biopsy-based clinical trials in ulcerative colitis.

Boland BS, Boyle DL, Sandborn WJ, Firestein GS, Levesque BG, Hillman J, Zhang B, Proudfoot J, Eckmann L, Ernst PB, Rivera-Nieves J, Pola S, Copur-Dahi N, Chang JT.

Aliment Pharmacol Ther. 2014 Sep;40(5):477-85. doi: 10.1111/apt.12862. Epub 2014 Jul 13.


Studies in human intestinal tissues: is it time to reemphasize research in human immunology?

Chang JT, Sandborn WJ, Ernst PB.

Gastroenterology. 2014 Jul;147(1):26-30. doi: 10.1053/j.gastro.2014.05.025. Epub 2014 May 27. No abstract available.


Extracellular adenosine regulates colitis through effects on lymphoid and nonlymphoid cells.

Kurtz CC, Drygiannakis I, Naganuma M, Feldman S, Bekiaris V, Linden J, Ware CF, Ernst PB.

Am J Physiol Gastrointest Liver Physiol. 2014 Aug 1;307(3):G338-46. doi: 10.1152/ajpgi.00404.2013. Epub 2014 May 29.


Ecto-5'-nucleotidase (CD73) regulates host inflammatory responses and exacerbates murine salmonellosis.

Alam MS, Kuo JL, Ernst PB, Derr-Castillo V, Pereira M, Gaines D, Costales M, Bigley E, Williams K.

Sci Rep. 2014 Mar 27;4:4486. doi: 10.1038/srep04486.


Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes during infection with Helicobacter pylori and mediates the recognition and engulfment of human apoptotic gastric epithelial cells.

Das S, Sarkar A, Ryan KA, Fox S, Berger AH, Juncadella IJ, Bimczok D, Smythies LE, Harris PR, Ravichandran KS, Crowe SE, Smith PD, Ernst PB.

FASEB J. 2014 May;28(5):2214-24. doi: 10.1096/fj.13-243238. Epub 2014 Feb 7.


Helicobacter pylori infection inhibits phagocyte clearance of apoptotic gastric epithelial cells.

Bimczok D, Smythies LE, Waites KB, Grams JM, Stahl RD, Mannon PJ, Peter S, Wilcox CM, Harris PR, Das S, Ernst PB, Smith PD.

J Immunol. 2013 Jun 15;190(12):6626-34. doi: 10.4049/jimmunol.1203330. Epub 2013 May 17.


A link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31.

Mauldin JP, Lu M, Das S, Park D, Ernst PB, Ravichandran KS.

Curr Biol. 2013 Jan 21;23(2):162-7. doi: 10.1016/j.cub.2012.11.049. Epub 2012 Dec 27.


Ultrasound-based molecular imaging and specific gene delivery to mesenteric vasculature by endothelial adhesion molecule targeted microbubbles in a mouse model of Crohn's disease.

Tlaxca JL, Rychak JJ, Ernst PB, Konkalmatt PR, Shevchenko TI, Pizarro TT, Rivera-Nieves J, Klibanov AL, Lawrence MB.

J Control Release. 2013 Feb 10;165(3):216-25. doi: 10.1016/j.jconrel.2012.10.021. Epub 2012 Nov 8. Erratum in: J Control Release. 2014 Jan 10;173:10. Pizzaro, Theresa T [corrected to Pizarro, Theresa T].


Comparative genome analysis of the high pathogenicity Salmonella Typhimurium strain UK-1.

Luo Y, Kong Q, Yang J, Mitra A, Golden G, Wanda SY, Roland KL, Jensen RV, Ernst PB, Curtiss R 3rd.

PLoS One. 2012;7(7):e40645. doi: 10.1371/journal.pone.0040645. Epub 2012 Jul 6.

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