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Items: 1 to 20 of 164


A passion for parasites.

Englund PT.

J Biol Chem. 2014 Dec 5;289(49):33712-29. doi: 10.1074/jbc.X114.620666. Epub 2014 Oct 21.


Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1.

Povelones ML, Tiengwe C, Gluenz E, Gull K, Englund PT, Jensen RE.

Mol Microbiol. 2013 Feb;87(4):713-29. doi: 10.1111/mmi.12089. Epub 2013 Jan 21.


Network news: the replication of kinetoplast DNA.

Jensen RE, Englund PT.

Annu Rev Microbiol. 2012;66:473-91. doi: 10.1146/annurev-micro-092611-150057. Review.


TbPIF8, a Trypanosoma brucei protein related to the yeast Pif1 helicase, is essential for cell viability and mitochondrial genome maintenance.

Wang J, Englund PT, Jensen RE.

Mol Microbiol. 2012 Feb;83(3):471-85. doi: 10.1111/j.1365-2958.2011.07938.x. Epub 2012 Jan 4.


Depletion of mitochondrial acyl carrier protein in bloodstream-form Trypanosoma brucei causes a kinetoplast segregation defect.

Clayton AM, Guler JL, Povelones ML, Gluenz E, Gull K, Smith TK, Jensen RE, Englund PT.

Eukaryot Cell. 2011 Mar;10(3):286-92. doi: 10.1128/EC.00290-10. Epub 2011 Jan 14.


The killing of African trypanosomes by ethidium bromide.

Roy Chowdhury A, Bakshi R, Wang J, Yildirir G, Liu B, Pappas-Brown V, Tolun G, Griffith JD, Shapiro TA, Jensen RE, Englund PT.

PLoS Pathog. 2010 Dec 16;6(12):e1001226. doi: 10.1371/journal.ppat.1001226.


The kinetoplast duplication cycle in Trypanosoma brucei is orchestrated by cytoskeleton-mediated cell morphogenesis.

Gluenz E, Povelones ML, Englund PT, Gull K.

Mol Cell Biol. 2011 Mar;31(5):1012-21. doi: 10.1128/MCB.01176-10. Epub 2010 Dec 20.


TbPIF1, a Trypanosoma brucei mitochondrial DNA helicase, is essential for kinetoplast minicircle replication.

Liu B, Yildirir G, Wang J, Tolun G, Griffith JD, Englund PT.

J Biol Chem. 2010 Mar 5;285(10):7056-66. doi: 10.1074/jbc.M109.084038. Epub 2009 Dec 30.


TbPIF5 is a Trypanosoma brucei mitochondrial DNA helicase involved in processing of minicircle Okazaki fragments.

Liu B, Wang J, Yildirir G, Englund PT.

PLoS Pathog. 2009 Sep;5(9):e1000589. doi: 10.1371/journal.ppat.1000589. Epub 2009 Sep 25.


Trypanosomes have six mitochondrial DNA helicases with one controlling kinetoplast maxicircle replication.

Liu B, Wang J, Yaffe N, Lindsay ME, Zhao Z, Zick A, Shlomai J, Englund PT.

Mol Cell. 2009 Aug 28;35(4):490-501. doi: 10.1016/j.molcel.2009.07.004. Epub 2009 Jul 30.


Silencing of genes required for glycosylphosphatidylinositol anchor biosynthesis in Burkitt lymphoma.

Hu R, Mukhina GL, Lee SH, Jones RJ, Englund PT, Brown P, Sharkis SJ, Buckley JT, Brodsky RA.

Exp Hematol. 2009 Apr;37(4):423-434.e2. doi: 10.1016/j.exphem.2009.01.003.


A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology.

Lindsay ME, Gluenz E, Gull K, Englund PT.

Mol Microbiol. 2008 Dec;70(6):1465-76. doi: 10.1111/j.1365-2958.2008.06493.x. Epub 2008 Oct 22.


What happens when Trypanosoma brucei leaves Africa.

Jensen RE, Simpson L, Englund PT.

Trends Parasitol. 2008 Oct;24(10):428-31. doi: 10.1016/ Epub 2008 Aug 18.


Detection of glycophospholipid anchors on proteins.

Doering TL, Englund PT, Hart GW.

Curr Protoc Protein Sci. 2001 May;Chapter 12:Unit 12.5. doi: 10.1002/0471140864.ps1205s02.


Identification of a bacterial-like HslVU protease in the mitochondria of Trypanosoma brucei and its role in mitochondrial DNA replication.

Li Z, Lindsay ME, Motyka SA, Englund PT, Wang CC.

PLoS Pathog. 2008 Apr 18;4(4):e1000048. doi: 10.1371/journal.ppat.1000048.


Detection of glycophospholipid anchors on proteins.

Doering TL, Englund PT, Hart GW.

Curr Protoc Mol Biol. 2001 May;Chapter 17:Unit17.8. doi: 10.1002/0471142727.mb1708s22.


The 3-hydroxyacyl-ACP dehydratase of mitochondrial fatty acid synthesis in Trypanosoma brucei.

Autio KJ, Guler JL, Kastaniotis AJ, Englund PT, Hiltunen JK.

FEBS Lett. 2008 Mar 5;582(5):729-33. doi: 10.1016/j.febslet.2008.01.051. Epub 2008 Feb 5.


Mitochondrial fatty acid synthesis is required for normal mitochondrial morphology and function in Trypanosoma brucei.

Guler JL, Kriegova E, Smith TK, Lukes J, Englund PT.

Mol Microbiol. 2008 Mar;67(5):1125-42. doi: 10.1111/j.1365-2958.2008.06112.x. Epub 2008 Jan 23.


Effect of hydroxyurea on procyclic Trypanosoma brucei: an unconventional mechanism for achieving synchronous growth.

Chowdhury AR, Zhao Z, Englund PT.

Eukaryot Cell. 2008 Feb;7(2):425-8. Epub 2007 Dec 14.

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