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World J Gastroenterol. 2017 Apr 21;23(15):2660-2672. doi: 10.3748/wjg.v23.i15.2660.

Endoscopic management of pancreatic fluid collections-revisited.

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Zaheer Nabi, Jahangeer Basha, D Nageshwar Reddy, Department of Gastroenterology, Asian Institute of Gastroenterology, Somajiguda 6-3-661, Hyderadad, India.


The development of pancreatic fluid collections (PFC) is one of the most common complications of acute severe pancreatitis. Most of the acute pancreatic fluid collections resolve and do not require endoscopic drainage. However, a substantial proportion of acute necrotic collections get walled off and may require drainage. Endoscopic drainage of PFC is now the preferred mode of drainage due to reduced morbidity and mortality as compared to surgical or percutaneous drainage. With the introduction of new metal stents, the efficiency of endoscopic drainage has improved and the task of direct endoscopic necrosectomy has become easier. The requirement of re-intervention is less with new metal stents as compared to plastic stents. However, endoscopic drainage is not free of adverse events. Severe complications including bleeding, perforation, sepsis and embolism have been described with endoscopic approach to PFC. Therefore, the endoscopic management of PFC is a multidisciplinary affair and involves interventional radiologists as well as GI surgeons to deal with unplanned adverse events and failures. In this review we discuss the recent advances and controversies in the endoscopic management of PFC.


Endotherapy; Necrosectomy; Pancreatic necrosis; Pseudocyst

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