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Items: 10


Animal-to-Human Dose Translation of Obiltoxaximab for Treatment of Inhalational Anthrax Under the US FDA Animal Rule.

Nagy CF, Mondick J, Serbina N, Casey LS, Carpenter SE, French J, Guttendorf R.

Clin Transl Sci. 2017 Jan;10(1):12-19. doi: 10.1111/cts.12433. Epub 2016 Dec 7.


Pharmacokinetics and Tolerability of Obiltoxaximab: A Report of 5 Healthy Volunteer Studies.

Nagy CF, Leach TS, Hoffman JH, Czech A, Carpenter SE, Guttendorf R.

Clin Ther. 2016 Sep;38(9):2083-2097.e7. doi: 10.1016/j.clinthera.2016.07.170. Epub 2016 Aug 24.


Efficacy Projection of Obiltoxaximab for Treatment of Inhalational Anthrax across a Range of Disease Severity.

Yamamoto BJ, Shadiack AM, Carpenter S, Sanford D, Henning LN, O'Connor E, Gonzales N, Mondick J, French J, Stark GV, Fisher AC, Casey LS, Serbina NV.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5787-95. doi: 10.1128/AAC.00972-16. Print 2016 Oct.


Obiltoxaximab Prevents Disseminated Bacillus anthracis Infection and Improves Survival during Pre- and Postexposure Prophylaxis in Animal Models of Inhalational Anthrax.

Yamamoto BJ, Shadiack AM, Carpenter S, Sanford D, Henning LN, Gonzales N, O'Connor E, Casey LS, Serbina NV.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5796-805. doi: 10.1128/AAC.01102-16. Print 2016 Oct.


Purification of antibody heteropolymers using hydrophobic interaction chromatography.

Kostareva I, Hung F, Campbell C.

J Chromatogr A. 2008 Jan 11;1177(2):254-64. Epub 2007 Oct 13.


A DeImmunized chimeric anti-C3b/iC3b monoclonal antibody enhances rituximab-mediated killing in NHL and CLL cells via complement activation.

Peng W, Zhang X, Mohamed N, Inghirami G, Takeshita K, Pecora A, Nardone LL, Pincus SE, Casey LS, Spitalny GL.

Cancer Immunol Immunother. 2005 Dec;54(12):1172-9. Epub 2005 Apr 22.


Heteropolymers: a novel technology against blood-borne infections.

Mohamed N, Jones SM, Casey LS, Pincus SE, Spitalny GL.

Curr Opin Mol Ther. 2005 Apr;7(2):144-50. Review.


A high-affinity monoclonal antibody to anthrax protective antigen passively protects rabbits before and after aerosolized Bacillus anthracis spore challenge.

Mohamed N, Clagett M, Li J, Jones S, Pincus S, D'Alia G, Nardone L, Babin M, Spitalny G, Casey L.

Infect Immun. 2005 Feb;73(2):795-802.


Evaluation of antigen-based heteropolymer for treatment of systemic lupus erythematosus in a nonhuman primate model.

Pincus SE, Lukacher N, Mohamed N, Sesay M, Zabinski R, Ebelle R, Duncan L, Li J, Chen X, Peng W, Adaelu J, Casey L, Porter JP, Spitalny G, Nardone LL.

Clin Immunol. 2002 Nov;105(2):141-54.


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