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Items: 1 to 20 of 66


Metabolic interactions between dynamic bacterial subpopulations.

Rosenthal AZ, Qi Y, Hormoz S, Park J, Li SH, Elowitz MB.

Elife. 2018 May 29;7. pii: e33099. doi: 10.7554/eLife.33099.


Morphogen gradient reconstitution reveals Hedgehog pathway design principles.

Li P, Markson JS, Wang S, Chen S, Vachharajani V, Elowitz MB.

Science. 2018 May 4;360(6388):543-548. doi: 10.1126/science.aao0645. Epub 2018 Apr 5.


Molecular Time Sharing through Dynamic Pulsing in Single Cells.

Park J, Dies M, Lin Y, Hormoz S, Smith-Unna SE, Quinodoz S, Hernández-Jiménez MJ, Garcia-Ojalvo J, Locke JCW, Elowitz MB.

Cell Syst. 2018 Feb 28;6(2):216-229.e15. doi: 10.1016/j.cels.2018.01.011. Epub 2018 Feb 14.


Dynamic Ligand Discrimination in the Notch Signaling Pathway.

Nandagopal N, Santat LA, LeBon L, Sprinzak D, Bronner ME, Elowitz MB.

Cell. 2018 Feb 8;172(4):869-880.e19. doi: 10.1016/j.cell.2018.01.002. Epub 2018 Feb 1.


An operational view of intercellular signaling pathways.

Antebi YE, Nandagopal N, Elowitz MB.

Curr Opin Syst Biol. 2017 Feb;1:16-24. doi: 10.1016/j.coisb.2016.12.003. Epub 2017 Feb 24.


Combinatorial Signal Perception in the BMP Pathway.

Antebi YE, Linton JM, Klumpe H, Bintu B, Gong M, Su C, McCardell R, Elowitz MB.

Cell. 2017 Sep 7;170(6):1184-1196.e24. doi: 10.1016/j.cell.2017.08.015.


Challenges and emerging directions in single-cell analysis.

Yuan GC, Cai L, Elowitz M, Enver T, Fan G, Guo G, Irizarry R, Kharchenko P, Kim J, Orkin S, Quackenbush J, Saadatpour A, Schroeder T, Shivdasani R, Tirosh I.

Genome Biol. 2017 May 8;18(1):84. doi: 10.1186/s13059-017-1218-y. Review.


Inferring Cell-State Transition Dynamics from Lineage Trees and Endpoint Single-Cell Measurements.

Hormoz S, Singer ZS, Linton JM, Antebi YE, Shraiman BI, Elowitz MB.

Cell Syst. 2016 Nov 23;3(5):419-433.e8. doi: 10.1016/j.cels.2016.10.015.


Synthetic recording and in situ readout of lineage information in single cells.

Frieda KL, Linton JM, Hormoz S, Choi J, Chow KK, Singer ZS, Budde MW, Elowitz MB, Cai L.

Nature. 2017 Jan 5;541(7635):107-111. doi: 10.1038/nature20777. Epub 2016 Nov 21.


Synthetic biology: Precision timing in a cell.

Gao XJ, Elowitz MB.

Nature. 2016 Oct 27;538(7626):462-463. doi: 10.1038/nature19478. Epub 2016 Oct 12. No abstract available.


Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment.

Kueh HY, Yui MA, Ng KK, Pease SS, Zhang JA, Damle SS, Freedman G, Siu S, Bernstein ID, Elowitz MB, Rothenberg EV.

Nat Immunol. 2016 Aug;17(8):956-65. doi: 10.1038/ni.3514. Epub 2016 Jul 4.


Central Dogma Goes Digital.

Lin Y, Elowitz MB.

Mol Cell. 2016 Mar 17;61(6):791-2. doi: 10.1016/j.molcel.2016.03.005.


Dynamics of epigenetic regulation at the single-cell level.

Bintu L, Yong J, Antebi YE, McCue K, Kazuki Y, Uno N, Oshimura M, Elowitz MB.

Science. 2016 Feb 12;351(6274):720-4. doi: 10.1126/science.aab2956.


Combinatorial gene regulation by modulation of relative pulse timing.

Lin Y, Sohn CH, Dalal CK, Cai L, Elowitz MB.

Nature. 2015 Nov 5;527(7576):54-8. doi: 10.1038/nature15710. Epub 2015 Oct 14.


Single-cell transcriptome analysis reveals dynamic changes in lncRNA expression during reprogramming.

Kim DH, Marinov GK, Pepke S, Singer ZS, He P, Williams B, Schroth GP, Elowitz MB, Wold BJ.

Cell Stem Cell. 2015 Jan 8;16(1):88-101. doi: 10.1016/j.stem.2014.11.005.


Synthetic biology of multicellular systems: new platforms and applications for animal cells and organisms.

Markson JS, Elowitz MB.

ACS Synth Biol. 2014 Dec 19;3(12):875-6. doi: 10.1021/sb500358y. No abstract available.


Polyphasic feedback enables tunable cellular timers.

Levine JH, Elowitz MB.

Curr Biol. 2014 Oct 20;24(20):R994-5. doi: 10.1016/j.cub.2014.08.030. Epub 2014 Oct 21.


Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states.

LeBon L, Lee TV, Sprinzak D, Jafar-Nejad H, Elowitz MB.

Elife. 2014 Sep 25;3:e02950. doi: 10.7554/eLife.02950. Erratum in: Elife. 2014;3:e04998.


Pulsatile dynamics in the yeast proteome.

Dalal CK, Cai L, Lin Y, Rahbar K, Elowitz MB.

Curr Biol. 2014 Sep 22;24(18):2189-2194. doi: 10.1016/j.cub.2014.07.076. Epub 2014 Sep 11.


Dynamic heterogeneity and DNA methylation in embryonic stem cells.

Singer ZS, Yong J, Tischler J, Hackett JA, Altinok A, Surani MA, Cai L, Elowitz MB.

Mol Cell. 2014 Jul 17;55(2):319-31. doi: 10.1016/j.molcel.2014.06.029.

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