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Items: 1 to 20 of 243


Affinity Inequality among Serum Antibodies That Originate in Lymphoid Germinal Centers.

Kang M, Eisen TJ, Eisen EA, Chakraborty AK, Eisen HN.

PLoS One. 2015 Oct 7;10(10):e0139222. doi: 10.1371/journal.pone.0139222. eCollection 2015.


Persistent Antigen and Prolonged AKT-mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells.

Li Y, Shen C, Zhu B, Shi F, Eisen HN, Chen J.

J Immunol. 2015 Aug 15;195(4):1591-8. doi: 10.4049/jimmunol.1500451. Epub 2015 Jul 10.


Manipulating the selection forces during affinity maturation to generate cross-reactive HIV antibodies.

Wang S, Mata-Fink J, Kriegsman B, Hanson M, Irvine DJ, Eisen HN, Burton DR, Wittrup KD, Kardar M, Chakraborty AK.

Cell. 2015 Feb 12;160(4):785-97. doi: 10.1016/j.cell.2015.01.027. Epub 2015 Feb 5.


Remembrance of immunology past: conversations with Herman Eisen.

Eisen HN, Schlesinger S.

Annu Rev Immunol. 2015;33:1-28. doi: 10.1146/annurev-immunol-111214-122349. Epub 2015 Jan 12.


Koch Institute Symposium on Cancer Immunology and Immunotherapy.

Drake A, Joshi NS, Szeto GL, Zhu E, Eisen HN, Irvine DJ.

Cancer Immunol Res. 2013 Oct;1:217-222.


Immunopaleontology reveals how affinity enhancement is achieved during affinity maturation of antibodies to influenza virus.

Eisen HN, Chakraborty AK.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):7-8. doi: 10.1073/pnas.1219396110. No abstract available.


Promiscuous binding of extracellular peptides to cell surface class I MHC protein.

Eisen HN, Hou XH, Shen C, Wang K, Tanguturi VK, Smith C, Kozyrytska K, Nambiar L, McKinley CA, Chen J, Cohen RJ.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4580-5. doi: 10.1073/pnas.1201586109. Epub 2012 Mar 7.


Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRs.

Stone JD, Artyomov MN, Chervin AS, Chakraborty AK, Eisen HN, Kranz DM.

J Immunol. 2011 Dec 15;187(12):6281-90. doi: 10.4049/jimmunol.1101734. Epub 2011 Nov 18.


Evolving concepts of specificity in immune reactions.

Eisen HN, Chakraborty AK.

Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22373-80. doi: 10.1073/pnas.1012051108. Epub 2010 Dec 20.


Antigen-bearing dendritic cells regulate the diverse pattern of memory CD8 T-cell development in different tissues.

Shen CH, Talay O, Mahajan VS, Leskov IB, Eisen HN, Chen J.

Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22587-92. doi: 10.1073/pnas.1016350108. Epub 2010 Dec 13.


Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation.

Mouquet H, Scheid JF, Zoller MJ, Krogsgaard M, Ott RG, Shukair S, Artyomov MN, Pietzsch J, Connors M, Pereyra F, Walker BD, Ho DD, Wilson PC, Seaman MS, Eisen HN, Chakraborty AK, Hope TJ, Ravetch JV, Wardemann H, Nussenzweig MC.

Nature. 2010 Sep 30;467(7315):591-5. doi: 10.1038/nature09385.


The impact of TCR-binding properties and antigen presentation format on T cell responsiveness.

Chervin AS, Stone JD, Holler PD, Bai A, Chen J, Eisen HN, Kranz DM.

J Immunol. 2009 Jul 15;183(2):1166-78. doi: 10.4049/jimmunol.0900054. Epub 2009 Jun 24.


Rapid tolerization of virus-activated tumor-specific CD8+ T cells in prostate tumors of TRAMP mice.

Bai A, Higham E, Eisen HN, Wittrup KD, Chen J.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13003-8. doi: 10.1073/pnas.0805599105. Epub 2008 Aug 22.


Stage-dependent reactivity of thymocytes to self-peptide--MHC complexes.

Leng Q, Ge Q, Nguyen T, Eisen HN, Chen J.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5038-43. Epub 2007 Mar 14.


Development of CD4+ T cells expressing a nominally MHC class I-restricted T cell receptor by two different mechanisms.

Ge Q, Holler PD, Mahajan VS, Nuygen T, Eisen HN, Chen J.

Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1822-7. Epub 2006 Jan 27.


Multiple intracellular routes in the cross-presentation of a soluble protein by murine dendritic cells.

Palliser D, Guillen E, Ju M, Eisen HN.

J Immunol. 2005 Feb 15;174(4):1879-87.


Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines.

Little SR, Lynn DM, Ge Q, Anderson DG, Puram SV, Chen J, Eisen HN, Langer R.

Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9534-9. Epub 2004 Jun 21.


Michael Heidelberger.

Eisen HN.

Biogr Mem Natl Acad Sci. 2001;80:122-40. No abstract available.


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