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Items: 1 to 20 of 307

1.

Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies.

Kouprina N, Petrov N, Molina O, Liskovykh M, Pesenti E, Ohzeki JI, Masumoto H, Earnshaw WC, Larionov V.

ACS Synth Biol. 2018 Aug 16. doi: 10.1021/acssynbio.8b00230. [Epub ahead of print]

PMID:
30075081
2.

Isolation of mitotic chromosomes from vertebrate cells and characterization of their proteome by mass spectrometry.

Samejima I, Earnshaw WC.

Methods Cell Biol. 2018;144:329-348. doi: 10.1016/bs.mcb.2018.03.021. Epub 2018 Apr 12.

PMID:
29804675
3.

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S.

Nat Commun. 2018 May 22;9(1):2071. doi: 10.1038/s41467-018-04198-5.

4.

Seh1 targets GATOR2 and Nup153 to mitotic chromosomes.

Platani M, Samejima I, Samejima K, Kanemaki MT, Earnshaw WC.

J Cell Sci. 2018 May 1;131(9). pii: jcs213140. doi: 10.1242/jcs.213140.

5.

Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies.

Pesenti E, Kouprina N, Liskovykh M, Aurich-Costa J, Larionov V, Masumoto H, Earnshaw WC, Molina O.

ACS Synth Biol. 2018 Apr 20;7(4):1116-1130. doi: 10.1021/acssynbio.8b00018. Epub 2018 Mar 29.

6.

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S.

Nat Commun. 2018 Mar 16;9(1):1107. doi: 10.1038/s41467-018-03441-3. Erratum in: Nat Commun. 2018 May 22;9(1):2071.

7.

Mps1 Phosphorylates Its N-Terminal Extension to Relieve Autoinhibition and Activate the Spindle Assembly Checkpoint.

Combes G, Barysz H, Garand C, Gama Braga L, Alharbi I, Thebault P, Murakami L, Bryne DP, Stankovic S, Eyers PA, Bolanos-Garcia VM, Earnshaw WC, Maciejowski J, Jallepalli PV, Elowe S.

Curr Biol. 2018 Mar 19;28(6):872-883.e5. doi: 10.1016/j.cub.2018.02.002. Epub 2018 Mar 1.

8.

HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry.

Ruppert JG, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash AA, Ohta S, Earnshaw WC.

EMBO J. 2018 Mar 15;37(6). pii: e97677. doi: 10.15252/embj.201797677. Epub 2018 Feb 21.

9.

Functional analysis after rapid degradation of condensins and 3D-EM reveals chromatin volume is uncoupled from chromosome architecture in mitosis.

Samejima K, Booth DG, Ogawa H, Paulson JR, Xie L, Watson CA, Platani M, Kanemaki MT, Earnshaw WC.

J Cell Sci. 2018 Feb 22;131(4). pii: jcs210187. doi: 10.1242/jcs.210187.

10.

A pathway for mitotic chromosome formation.

Gibcus JH, Samejima K, Goloborodko A, Samejima I, Naumova N, Nuebler J, Kanemaki MT, Xie L, Paulson JR, Earnshaw WC, Mirny LA, Dekker J.

Science. 2018 Feb 9;359(6376). pii: eaao6135. doi: 10.1126/science.aao6135. Epub 2018 Jan 18.

11.

Mitotic post-translational modifications of histones promote chromatin compaction in vitro.

Zhiteneva A, Bonfiglio JJ, Makarov A, Colby T, Vagnarelli P, Schirmer EC, Matic I, Earnshaw WC.

Open Biol. 2017 Sep;7(9). pii: 170076. doi: 10.1098/rsob.170076.

12.

Use of Mass Spectrometry to Study the Centromere and Kinetochore.

Samejima I, Platani M, Earnshaw WC.

Prog Mol Subcell Biol. 2017;56:3-27. doi: 10.1007/978-3-319-58592-5_1.

PMID:
28840231
13.

Ki-67 and the Chromosome Periphery Compartment in Mitosis.

Booth DG, Earnshaw WC.

Trends Cell Biol. 2017 Dec;27(12):906-916. doi: 10.1016/j.tcb.2017.08.001. Epub 2017 Aug 23. Review.

PMID:
28838621
14.

Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System.

Lee NCO, Kim JH, Petrov NS, Lee HS, Masumoto H, Earnshaw WC, Larionov V, Kouprina N.

ACS Synth Biol. 2018 Jan 19;7(1):63-74. doi: 10.1021/acssynbio.7b00209. Epub 2017 Aug 24.

15.

Using human artificial chromosomes to study centromere assembly and function.

Molina O, Kouprina N, Masumoto H, Larionov V, Earnshaw WC.

Chromosoma. 2017 Oct;126(5):559-575. doi: 10.1007/s00412-017-0633-x. Epub 2017 Jul 7. Review.

PMID:
28688039
16.

Molecular basis for Cdk1-regulated timing of Mis18 complex assembly and CENP-A deposition.

Spiller F, Medina-Pritchard B, Abad MA, Wear MA, Molina O, Earnshaw WC, Jeyaprakash AA.

EMBO Rep. 2017 Jun;18(6):894-905. doi: 10.15252/embr.201643564. Epub 2017 Apr 4.

17.

Stepwise unfolding supports a subunit model for vertebrate kinetochores.

Vargiu G, Makarov AA, Allan J, Fukagawa T, Booth DG, Earnshaw WC.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3133-3138. doi: 10.1073/pnas.1614145114. Epub 2017 Mar 6.

18.

Nano Random Forests to mine protein complexes and their relationships in quantitative proteomics data.

Montaño-Gutierrez LF, Ohta S, Kustatscher G, Earnshaw WC, Rappsilber J.

Mol Biol Cell. 2017 Mar 1;28(5):673-680. doi: 10.1091/mbc.E16-06-0370. Epub 2017 Jan 5.

19.

PREditOR: a synthetic biology approach to removing heterochromatin from cells.

Molina O, Carmena M, Maudlin IE, Earnshaw WC.

Chromosome Res. 2016 Dec;24(4):495-509. Epub 2016 Dec 6.

20.

Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance.

Molina O, Vargiu G, Abad MA, Zhiteneva A, Jeyaprakash AA, Masumoto H, Kouprina N, Larionov V, Earnshaw WC.

Nat Commun. 2016 Nov 14;7:13334. doi: 10.1038/ncomms13334.

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